Best TWAS P=1.02e-11 · Best GWAS P=2.79e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PRIM1 | 0.31 | 0.24 | enet | 7 | 0.24 | 1.1e-28 | 6.7 | -6.8 | 1.0e-11 | -1.00 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Muscle Skeletal | ITGA7 | 0.08 | 0.09 | enet | 15 | 0.06 | 6.8e-07 | -5.2 | 5.2 | 1.8e-07 | -0.02 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ITGA7 | 0.04 | 0.01 | blup | 68 | 0.01 | 9.3e-03 | 4.3 | 5.2 | 1.8e-07 | -0.05 | 0.01 | 0.73 | TRUE |