Best TWAS P=1.13e-08 · Best GWAS P=1.72e-10 conditioned to 0.000897
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LYSMD4 | 0.23 | 0.13 | enet | 26 | 0.20 | 1.9e-23 | 3.9 | 5.7 | 1.1e-08 | 0.02 | 0.80 | 0.18 | TRUE |
| 2 | YFS | Blood | IGF1R | 0.14 | 0.09 | enet | 25 | 0.12 | 6.8e-36 | 3.7 | -5.5 | 3.0e-08 | -0.71 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LYSMD4 | 0.10 | 0.07 | blup | 57 | 0.11 | 7.7e-13 | 4.2 | 5.2 | 2.2e-07 | 0.03 | 0.61 | 0.31 | FALSE |