Best TWAS P=1.35e-07 · Best GWAS P=2.29e-09 conditioned to 4.29e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | LITAF | 0.36 | 0.30 | lasso | 4 | 0.30 | 1.2e-24 | 5.1 | -5.2 | 2.4e-07 | -0.04 | 0.07 | 0.92 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | RP11-876N24.5 | 0.15 | 0.11 | enet | 19 | 0.12 | 1.4e-06 | 3.5 | 5.3 | 1.4e-07 | 0.07 | 0.03 | 0.97 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | LITAF | 0.18 | 0.13 | lasso | 1 | 0.12 | 5.4e-10 | 5.1 | -5.1 | 2.8e-07 | -0.05 | 0.07 | 0.92 | FALSE |
| 4 | METSIM | Adipose | LITAF | 0.22 | 0.18 | lasso | 6 | 0.19 | 3.7e-27 | 5.2 | -5.2 | 1.7e-07 | -0.03 | 0.05 | 0.95 | TRUE |