[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr16:2,705,523-5,281,856

Best TWAS P=1.29e-22 · Best GWAS P=7.25e-26 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CORO7	0.08	0.08	lasso	2	0.06	4.3e-08	7.3	-7.3	2.7e-13	-0.64	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	DNAJA3	0.23	0.29	lasso	3	0.29	1.2e-35	8.3	8.5	1.3e-17	0.59	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	HMOX2	0.13	0.05	lasso	6	0.04	2.2e-04	8.3	9.0	1.9e-19	0.65	0.95	0.03	FALSE
4	GTEx	Adipose Subcutaneous	NMRAL1	0.31	0.33	lasso	4	0.35	9.0e-30	7.4	8.1	6.0e-16	0.56	1.00	0.00	FALSE
5	GTEx	Adipose Subcutaneous	PAM16	0.17	0.09	lasso	7	0.10	8.6e-09	6.7	-7.8	4.8e-15	-0.56	0.86	0.14	FALSE
6	GTEx	Adipose Visceral Omentum	NMRAL1	0.36	0.27	enet	20	0.27	3.7e-14	8.2	8.3	1.1e-16	0.56	1.00	0.00	FALSE
7	GTEx	Artery Aorta	NMRAL1	0.43	0.42	lasso	8	0.42	4.7e-25	7.4	7.6	2.2e-14	0.54	1.00	0.00	FALSE
8	GTEx	Artery Aorta	PAM16	0.22	0.10	enet	15	0.11	8.6e-07	7.5	-5.6	1.8e-08	-0.58	0.77	0.15	FALSE
9	GTEx	Artery Coronary	NMRAL1	0.40	0.34	lasso	5	0.34	3.5e-12	8.0	8.2	1.6e-16	0.55	1.00	0.00	FALSE
10	GTEx	Artery Tibial	CDIP1	0.14	0.14	lasso	3	0.16	1.0e-12	8.2	-8.8	1.6e-18	-0.62	1.00	0.00	FALSE
11	GTEx	Artery Tibial	HMOX2	0.19	0.14	enet	6	0.15	1.1e-11	3.0	6.2	5.1e-10	0.52	1.00	0.00	FALSE
12	GTEx	Artery Tibial	NMRAL1	0.38	0.30	enet	15	0.36	1.2e-29	7.4	8.1	6.5e-16	0.50	1.00	0.00	TRUE
13	GTEx	Artery Tibial	PAM16	0.23	0.06	lasso	9	0.10	4.3e-08	5.7	-7.5	7.4e-14	-0.53	0.10	0.88	FALSE
14	GTEx	Brain Cerebellar Hemisphere	CDIP1	0.47	0.47	lasso	6	0.52	1.2e-15	7.4	8.2	3.5e-16	0.67	0.82	0.18	FALSE
15	GTEx	Brain Cerebellar Hemisphere	NMRAL1	0.62	0.66	lasso	3	0.68	2.2e-23	7.4	7.8	4.6e-15	0.56	0.99	0.01	FALSE
16	GTEx	Brain Cerebellum	CDIP1	0.47	0.54	lasso	7	0.52	8.3e-18	7.4	8.3	9.1e-17	0.62	0.97	0.03	FALSE
17	GTEx	Brain Cerebellum	HMOX2	0.21	0.15	lasso	3	0.14	7.2e-05	7.6	7.7	1.6e-14	0.67	0.32	0.44	FALSE
18	GTEx	Brain Cerebellum	NMRAL1	0.81	0.55	lasso	10	0.62	4.6e-23	8.3	8.8	1.2e-18	0.64	0.99	0.01	FALSE
19	GTEx	Brain Nucleus accumbens basal ganglia	HMOX2	0.28	-0.01	lasso	5	-0.01	7.1e-01	8.2	-7.5	4.8e-14	-0.55	0.06	0.30	FALSE
20	GTEx	Breast Mammary Tissue	NMRAL1	0.17	0.18	lasso	2	0.15	5.2e-08	7.4	7.4	1.2e-13	0.53	0.98	0.00	FALSE
21	GTEx	Breast Mammary Tissue (Male)	NMRAL1	0.20	0.11	lasso	4	0.10	2.4e-03	8.2	7.7	9.9e-15	0.54	0.10	0.05	FALSE
22	GTEx	Breast Mammary Tissue (Female)	NMRAL1	0.29	0.01	lasso	6	0.00	2.7e-01	5.6	5.9	3.1e-09	0.40	0.08	0.08	FALSE
23	GTEx	Cells EBV-transformed lymphocytes	CDIP1	0.16	0.10	lasso	7	0.06	6.8e-03	7.7	-8.7	4.2e-18	-0.73	0.20	0.48	FALSE
24	GTEx	Cells Transformed fibroblasts	CDIP1	0.33	0.35	lasso	3	0.36	1.3e-28	8.2	-8.7	3.9e-18	-0.62	1.00	0.00	FALSE
25	GTEx	Cells Transformed fibroblasts	NMRAL1	0.15	0.12	lasso	5	0.12	1.6e-09	7.4	7.7	1.1e-14	0.52	1.00	0.00	FALSE
26	GTEx	Cells Transformed fibroblasts	PAM16	0.12	0.06	lasso	8	0.08	1.6e-06	6.7	-7.7	9.7e-15	-0.62	0.81	0.08	FALSE
27	GTEx	Cells Transformed fibroblasts	RP11-95P2.1	0.13	0.11	lasso	3	0.12	2.0e-09	-5.1	5.8	8.8e-09	0.07	1.00	0.00	TRUE
28	GTEx	Colon Sigmoid	CDIP1	0.25	0.04	lasso	6	0.04	1.6e-02	8.5	-7.8	5.2e-15	-0.67	0.07	0.30	FALSE
29	GTEx	Colon Sigmoid	NMRAL1	0.43	0.35	lasso	5	0.31	1.7e-11	7.4	7.8	5.0e-15	0.55	0.99	0.01	FALSE
30	GTEx	Colon Transverse	CDIP1	0.21	0.07	lasso	4	0.09	4.5e-05	9.0	-8.4	4.2e-17	-0.64	0.86	0.03	FALSE
31	GTEx	Colon Transverse	NMRAL1	0.38	0.19	enet	31	0.19	2.3e-09	8.2	7.9	2.6e-15	0.51	1.00	0.00	FALSE
32	GTEx	Colon Transverse	PAM16	0.29	0.14	lasso	6	0.16	6.5e-08	6.6	-8.0	1.5e-15	-0.55	0.10	0.87	TRUE
33	GTEx	Esophagus Gastroesophageal Junction	CDIP1	0.25	0.24	lasso	5	0.25	1.2e-09	8.8	-8.8	1.0e-18	-0.71	0.95	0.04	FALSE
34	GTEx	Esophagus Gastroesophageal Junction	NMRAL1	0.47	0.28	lasso	4	0.26	4.3e-10	8.2	8.1	4.0e-16	0.53	1.00	0.00	FALSE
35	GTEx	Esophagus Mucosa	NMRAL1	0.23	0.13	lasso	4	0.12	2.7e-08	8.2	8.5	2.7e-17	0.58	1.00	0.00	FALSE
36	GTEx	Esophagus Mucosa	ZNF75A	0.23	0.14	enet	15	0.16	3.7e-11	-4.4	5.3	1.1e-07	-0.02	0.32	0.65	FALSE
37	GTEx	Esophagus Muscularis	CDIP1	0.35	0.16	lasso	11	0.20	3.9e-12	9.0	-8.7	2.8e-18	-0.68	0.99	0.01	FALSE
38	GTEx	Esophagus Muscularis	NMRAL1	0.30	0.35	enet	16	0.33	7.2e-21	7.4	7.5	5.9e-14	0.51	1.00	0.00	FALSE
39	GTEx	Esophagus Muscularis	PAM16	0.17	0.07	enet	20	0.12	1.8e-07	7.4	-6.2	4.3e-10	-0.60	0.16	0.82	FALSE
40	GTEx	Heart Atrial Appendage	NMRAL1	0.27	0.25	lasso	2	0.23	1.1e-10	7.4	7.6	4.2e-14	0.54	1.00	0.00	FALSE
41	GTEx	Heart Left Ventricle	NMRAL1	0.36	0.26	enet	12	0.28	4.4e-15	8.8	8.9	4.6e-19	0.66	1.00	0.00	FALSE
42	GTEx	Lung	CDIP1	0.10	0.06	enet	13	0.08	1.5e-06	9.0	-8.3	9.0e-17	-0.59	0.92	0.04	FALSE
43	GTEx	Lung	NMRAL1	0.16	0.11	enet	3	0.13	3.4e-10	7.4	8.1	8.1e-16	0.56	1.00	0.00	FALSE
44	GTEx	Lung	PAM16	0.17	0.08	lasso	5	0.10	7.4e-08	7.5	-7.8	4.3e-15	-0.59	0.76	0.23	FALSE
45	GTEx	Muscle Skeletal	CDIP1	0.07	0.07	lasso	2	0.06	6.1e-07	8.0	-7.9	2.1e-15	-0.52	0.99	0.00	FALSE
46	GTEx	Muscle Skeletal	NMRAL1	0.27	0.22	enet	28	0.31	2.0e-30	8.8	9.8	1.3e-22	0.73	1.00	0.00	TRUE
47	GTEx	Nerve Tibial	CDIP1	0.20	0.12	lasso	5	0.13	1.4e-09	9.0	-8.2	2.3e-16	-0.63	0.96	0.03	FALSE
48	GTEx	Nerve Tibial	HMOX2	0.24	0.07	lasso	7	0.07	1.3e-05	8.2	9.6	1.1e-21	0.58	0.69	0.30	FALSE
49	GTEx	Nerve Tibial	NMRAL1	0.32	0.37	lasso	3	0.36	5.2e-27	7.4	7.8	7.0e-15	0.55	1.00	0.00	FALSE
50	GTEx	Nerve Tibial	PAM16	0.34	0.14	lasso	7	0.25	5.8e-18	7.4	-7.7	1.9e-14	-0.61	0.39	0.61	FALSE
51	GTEx	Pancreas	NMRAL1	0.31	0.12	enet	14	0.13	5.4e-06	8.2	7.4	2.0e-13	0.53	0.78	0.16	FALSE
52	GTEx	Pancreas	PAM16	0.19	0.02	lasso	4	0.04	7.9e-03	7.5	-7.0	2.3e-12	-0.55	0.13	0.62	FALSE
53	GTEx	Pituitary	NMRAL1	0.31	0.18	enet	12	0.23	1.9e-06	8.3	7.7	1.4e-14	0.60	0.20	0.72	FALSE
54	GTEx	Pituitary	PAM16	0.36	0.01	enet	21	0.21	6.4e-06	7.4	-5.9	3.3e-09	-0.68	0.02	0.87	FALSE
55	GTEx	Skin Not Sun Exposed Suprapubic	NMRAL1	0.19	0.12	lasso	3	0.11	1.3e-06	8.2	8.3	1.4e-16	0.56	0.97	0.02	FALSE
56	GTEx	Skin Sun Exposed Lower leg	CDIP1	0.08	0.06	lasso	3	0.05	6.8e-05	8.2	-8.2	1.9e-16	-0.55	0.64	0.04	FALSE
57	GTEx	Skin Sun Exposed Lower leg	NMRAL1	0.12	0.05	enet	9	0.04	1.6e-04	5.7	7.1	9.7e-13	0.43	0.98	0.01	FALSE
58	GTEx	Skin Sun Exposed Lower leg	PAM16	0.12	0.02	lasso	10	0.06	9.9e-06	2.1	-7.3	3.8e-13	-0.57	0.09	0.76	TRUE
59	GTEx	Spleen	NMRAL1	0.35	0.20	lasso	6	0.23	1.6e-06	8.2	6.3	4.0e-10	0.34	0.11	0.05	FALSE
60	GTEx	Stomach	NMRAL1	0.16	0.18	lasso	1	0.16	6.5e-08	8.2	8.2	1.6e-16	0.55	0.95	0.01	FALSE
61	GTEx	Stomach	PAM16	0.19	0.08	lasso	5	0.09	3.9e-05	5.7	-6.9	6.4e-12	-0.56	0.36	0.41	FALSE
62	GTEx	Testis	NMRAL1	0.27	0.20	enet	6	0.22	2.4e-10	8.2	8.9	6.2e-19	0.60	0.78	0.22	FALSE
63	GTEx	Thyroid	CDIP1	0.15	0.14	lasso	3	0.15	1.5e-11	8.8	-8.9	6.2e-19	-0.64	0.76	0.24	FALSE
64	GTEx	Thyroid	HMOX2	0.12	0.06	lasso	3	0.04	3.3e-04	8.5	7.4	1.3e-13	0.69	0.22	0.28	FALSE
65	GTEx	Thyroid	NMRAL1	0.18	0.14	lasso	3	0.15	2.4e-11	8.5	8.9	4.5e-19	0.74	1.00	0.00	FALSE
66	GTEx	Thyroid	ZNF75A	0.11	0.07	enet	16	0.09	3.9e-07	-4.3	5.2	2.1e-07	-0.01	0.31	0.66	FALSE
67	GTEx	Thyroid	PAM16	0.35	0.14	lasso	7	0.21	4.3e-16	5.7	-7.3	2.0e-13	-0.59	0.92	0.08	FALSE
68	GTEx	Thyroid	RP11-95P2.1	0.15	0.10	lasso	5	0.10	3.9e-08	-8.3	7.9	2.6e-15	0.13	0.94	0.00	TRUE
69	GTEx	Vagina	PAM16	0.52	0.25	enet	24	0.24	4.2e-06	7.5	-6.8	1.2e-11	-0.55	0.14	0.43	TRUE
70	GTEx	Whole Blood	NMRAL1	0.19	0.14	lasso	5	0.20	3.6e-18	8.0	5.5	3.1e-08	0.34	1.00	0.00	FALSE
71	GTEx	Whole Blood	PAM16	0.10	0.05	lasso	5	0.06	2.2e-06	7.5	-8.4	5.5e-17	-0.70	0.01	0.98	FALSE
72	METSIM	Adipose	CDIP1	0.07	0.06	lasso	5	0.08	2.8e-12	9.1	-9.2	2.3e-20	-0.69	1.00	0.00	FALSE
73	METSIM	Adipose	NMRAL1	0.18	0.22	bslmm	447	0.22	8.8e-33	8.3	8.5	1.2e-17	0.56	1.00	0.00	TRUE
74	METSIM	Adipose	RP11-95P2.1	0.10	0.01	bslmm	375	0.02	1.0e-04	-4.7	5.4	8.5e-08	0.38	0.64	0.01	TRUE
75	METSIM	Adipose	ZNF75A	0.07	0.06	lasso	5	0.07	2.5e-10	-4.4	5.7	1.2e-08	-0.02	0.17	0.82	FALSE
76	ROSMAP	Brain Pre-frontal Cortex	CDIP1	0.13	0.18	lasso	2	0.17	3.6e-21	8.0	8.1	6.0e-16	0.57	1.00	0.00	FALSE
77	ROSMAP	Brain Pre-frontal Cortex	NMRAL1	0.31	0.25	lasso	6	0.30	8.0e-40	8.3	6.3	3.9e-10	0.40	1.00	0.00	FALSE
78	ROSMAP	Brain Pre-frontal Cortex	VASN	0.08	0.04	bslmm	410	0.04	6.8e-06	8.9	-8.0	1.5e-15	-0.70	0.02	0.98	FALSE
79	ROSMAP	Brain Pre-frontal Cortex	CORO7	0.19	0.29	bslmm	426	0.29	5.8e-38	7.7	-7.7	9.5e-15	-0.69	1.00	0.00	FALSE
80	YFS	Blood	CORO7	0.07	0.06	enet	15	0.06	1.5e-19	7.4	-7.6	2.4e-14	-0.64	1.00	0.00	FALSE
81	YFS	Blood	NMRAL1	0.25	0.22	lasso	7	0.32	6.7e-107	8.3	5.1	2.9e-07	0.32	1.00	0.00	FALSE
82	YFS	Blood	ZNF75A	0.08	0.08	lasso	5	0.09	3.9e-27	-4.4	5.1	2.8e-07	0.00	0.37	0.59	FALSE
83	The Cancer Genome Atlas	Breast Invasive Carcinoma	C16orf5	0.02	0.03	blup	37	0.03	9.7e-08	8.2	-8.3	9.6e-17	-0.57	0.09	0.91	FALSE
84	The Cancer Genome Atlas	Glioblastoma Multiforme	CORO7	0.12	0.06	lasso	6	0.06	8.3e-03	8.2	-9.5	1.9e-21	-0.76	0.05	0.23	FALSE
85	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C16orf5	0.02	0.02	lasso	3	0.02	4.5e-03	8.8	-8.8	1.8e-18	-0.64	0.02	0.93	FALSE
86	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C16orf5	0.09	0.10	lasso	2	0.06	1.6e-04	9.1	-9.1	6.1e-20	-0.68	0.00	0.99	FALSE
87	The Cancer Genome Atlas	Brain Lower Grade Glioma	CORO7	0.26	0.43	lasso	3	0.44	5.0e-54	7.7	-8.2	2.3e-16	-0.69	1.00	0.00	FALSE
88	The Cancer Genome Atlas	Brain Lower Grade Glioma	HMOX2	0.02	0.03	lasso	2	0.02	3.9e-03	9.0	8.8	1.3e-18	0.61	0.02	0.94	FALSE
89	The Cancer Genome Atlas	Brain Lower Grade Glioma	NLRC3	0.32	0.28	enet	17	0.35	8.2e-41	-4.4	5.2	2.1e-07	-0.04	0.03	0.91	TRUE
90	The Cancer Genome Atlas	Brain Lower Grade Glioma	NMRAL1	0.17	0.20	enet	14	0.21	3.3e-23	8.3	7.5	5.8e-14	0.48	0.80	0.20	FALSE
91	The Cancer Genome Atlas	Brain Lower Grade Glioma	TIGD7	0.02	0.03	blup	34	0.03	3.6e-04	-5.2	-5.6	2.7e-08	-0.01	0.01	0.97	FALSE
92	The Cancer Genome Atlas	Lung Adenocarcinoma	C16orf5	0.03	0.03	lasso	2	0.02	1.3e-03	8.0	-8.1	3.7e-16	-0.55	0.05	0.85	FALSE
93	The Cancer Genome Atlas	Prostate Adenocarcinoma	C16orf5	0.07	0.07	blup	37	0.07	1.1e-07	8.2	-8.7	3.6e-18	-0.61	0.02	0.98	FALSE
94	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC342346	0.06	0.02	blup	34	0.02	1.2e-03	8.2	-7.6	2.6e-14	-0.53	0.02	0.98	FALSE
95	The Cancer Genome Atlas	Prostate Adenocarcinoma	NMRAL1	0.07	0.06	blup	32	0.05	2.5e-06	3.1	-5.3	1.3e-07	-0.49	0.58	0.29	FALSE
96	The Cancer Genome Atlas	Prostate Adenocarcinoma	TIGD7	0.05	0.05	enet	4	0.05	2.8e-06	5.5	-6.1	1.4e-09	-0.01	0.00	1.00	TRUE
97	The Cancer Genome Atlas	Testicular Germ Cell Tumors	TIMM16	0.17	0.04	enet	4	0.06	5.1e-03	4.9	-6.6	4.5e-11	-0.62	0.04	0.06	FALSE
98	The Cancer Genome Atlas	Thyroid Carcinoma	C16orf5	0.05	0.07	enet	4	0.07	1.1e-07	9.0	-9.1	5.8e-20	-0.65	0.01	0.99	FALSE