Best TWAS P=4.72e-19 · Best GWAS P=2.52e-32 conditioned to 7.59e-11
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Transverse | KCNJ2 | 0.12 | 0.06 | enet | 16 | 0.07 | 0.00024 | 6.3 | -8.9 | 4.7e-19 | -0.58 | 0.12 | 0.44 | TRUE |
2 | GTEx | Muscle Skeletal | KCNJ2 | 0.08 | 0.04 | lasso | 3 | 0.04 | 0.00008 | -5.4 | 7.8 | 5.4e-15 | 0.75 | 0.28 | 0.40 | TRUE |