Best TWAS P=1.44e-19 · Best GWAS P=3.89e-17 conditioned to 0.0102
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MRPS7 | 0.09 | 0.10 | lasso | 3 | 0.09 | 1.7e-11 | -4.6 | 5.2 | 2.5e-07 | -0.01 | 0.93 | 0.07 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | RNF157 | 0.20 | 0.06 | enet | 14 | 0.10 | 1.0e-08 | 8.4 | -9.1 | 1.4e-19 | -0.75 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Adipose Subcutaneous | RNF157-AS1 | 0.24 | 0.11 | enet | 33 | 0.11 | 2.0e-09 | -4.8 | -8.0 | 9.4e-16 | -0.59 | 0.20 | 0.80 | FALSE |
| 4 | GTEx | Brain Cerebellar Hemisphere | GGA3 | 0.22 | 0.00 | lasso | 4 | 0.00 | 3.0e-01 | -5.0 | -6.0 | 1.5e-09 | -0.01 | 0.04 | 0.34 | FALSE |
| 5 | GTEx | Brain Cerebellar Hemisphere | NUP85 | 0.52 | 0.18 | lasso | 9 | 0.24 | 9.9e-07 | -4.5 | -5.3 | 1.0e-07 | 0.06 | 0.22 | 0.74 | FALSE |
| 6 | GTEx | Liver | SLC25A19 | 0.18 | 0.15 | lasso | 6 | 0.11 | 5.6e-04 | -4.5 | 5.2 | 1.7e-07 | -0.01 | 0.09 | 0.67 | FALSE |
| 7 | GTEx | Whole Blood | MIF4GD | 0.07 | 0.06 | lasso | 4 | 0.04 | 1.2e-04 | -6.4 | 6.3 | 3.5e-10 | 0.01 | 0.04 | 0.95 | FALSE |
| 8 | METSIM | Adipose | GGA3 | 0.06 | 0.03 | blup | 374 | 0.06 | 8.8e-09 | -4.7 | -6.0 | 2.2e-09 | 0.06 | 0.46 | 0.54 | FALSE |
| 9 | METSIM | Adipose | RNF157 | 0.18 | 0.08 | lasso | 6 | 0.11 | 2.4e-16 | 8.3 | -9.0 | 1.7e-19 | -0.81 | 0.00 | 1.00 | FALSE |
| 10 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FAM100B | 0.04 | 0.01 | blup | 51 | 0.04 | 5.2e-09 | -3.4 | 6.2 | 5.5e-10 | 0.13 | 0.99 | 0.00 | FALSE |
| 11 | The Cancer Genome Atlas | Breast Invasive Carcinoma | MIF4GD | 0.01 | 0.00 | blup | 28 | 0.01 | 6.0e-03 | -4.7 | 6.2 | 4.9e-10 | 0.00 | 0.02 | 0.53 | FALSE |
| 12 | The Cancer Genome Atlas | Colon Adenocarcinoma | MRPS7 | 0.12 | 0.05 | blup | 27 | 0.07 | 7.9e-05 | -4.6 | 5.7 | 1.0e-08 | -0.03 | 0.03 | 0.95 | FALSE |
| 13 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NUP85 | 0.04 | 0.03 | blup | 28 | 0.05 | 4.5e-06 | -6.2 | -5.7 | 1.1e-08 | 0.03 | 0.01 | 0.99 | FALSE |
| 14 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NUP85 | 0.06 | 0.07 | blup | 26 | 0.09 | 1.9e-10 | -4.5 | -5.5 | 3.3e-08 | 0.01 | 0.05 | 0.95 | FALSE |
| 15 | The Cancer Genome Atlas | Brain Lower Grade Glioma | QRICH2 | 0.06 | 0.00 | enet | 7 | 0.04 | 1.3e-05 | -5.0 | 6.7 | 2.4e-11 | 0.25 | 0.07 | 0.18 | FALSE |
| 16 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | SLC25A19 | 0.12 | 0.16 | enet | 8 | 0.18 | 8.0e-09 | -6.2 | 6.5 | 6.2e-11 | -0.01 | 0.04 | 0.96 | TRUE |
| 17 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | MRPS7 | 0.10 | 0.10 | enet | 6 | 0.09 | 2.3e-04 | -4.6 | 5.3 | 9.6e-08 | -0.02 | 0.06 | 0.81 | FALSE |
| 18 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM100B | 0.09 | 0.02 | blup | 48 | 0.07 | 4.5e-08 | -5.0 | 5.5 | 4.4e-08 | -0.02 | 0.99 | 0.00 | FALSE |
| 19 | The Cancer Genome Atlas | Thyroid Carcinoma | MIF4GD | 0.03 | 0.02 | blup | 28 | 0.02 | 9.8e-03 | -6.3 | 5.8 | 6.1e-09 | -0.02 | 0.02 | 0.65 | FALSE |
| 20 | The Cancer Genome Atlas | Thyroid Carcinoma | NUP85 | 0.08 | 0.09 | lasso | 3 | 0.10 | 4.7e-10 | -4.5 | -5.3 | 1.0e-07 | 0.03 | 0.06 | 0.94 | FALSE |
| 21 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NUP85 | 0.10 | 0.02 | blup | 26 | 0.03 | 5.4e-02 | -4.6 | -5.7 | 9.5e-09 | 0.01 | 0.01 | 0.60 | FALSE |