Best TWAS P=7.87e-46 · Best GWAS P=1.01e-50 conditioned to 1.22e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | EYA2 | 0.42 | 0.32 | lasso | 6 | 0.34 | 1.6e-19 | -11.9 | 11.9 | 1.0e-32 | -0.73 | 1.00 | 0.0 | TRUE |
| 2 | GTEx | Thyroid | EYA2 | 0.29 | 0.16 | enet | 51 | 0.15 | 1.0e-11 | 3.9 | 6.5 | 6.0e-11 | -0.23 | 1.00 | 0.0 | FALSE |
| 3 | METSIM | Adipose | EYA2 | 0.05 | 0.01 | enet | 21 | 0.03 | 6.6e-05 | -14.1 | 14.2 | 7.9e-46 | -0.55 | 0.05 | 0.9 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | EYA2 | 0.36 | 0.14 | enet | 18 | 0.28 | 9.0e-28 | 3.9 | 5.9 | 3.6e-09 | -0.26 | 1.00 | 0.0 | FALSE |