Best TWAS P=6.6e-13 · Best GWAS P=9.58e-15 conditioned to 2.16e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | LPIN3 | 0.17 | 0.13 | lasso | 6 | 0.15 | 6.5e-12 | 4.6 | 5.9 | 3.3e-09 | -0.55 | 0.25 | 0.75 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZHX3 | 0.03 | 0.03 | lasso | 4 | 0.02 | 1.2e-05 | 7.1 | -7.0 | 1.8e-12 | 0.56 | 0.13 | 0.87 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PRO0628 | 0.05 | 0.01 | lasso | 2 | 0.02 | 4.5e-03 | 5.6 | 7.2 | 6.6e-13 | -0.51 | 0.02 | 0.26 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PLCG1 | 0.03 | 0.00 | blup | 35 | 0.02 | 3.5e-03 | 6.7 | -5.9 | 2.9e-09 | 0.68 | 0.02 | 0.44 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZHX3 | 0.05 | 0.06 | lasso | 2 | 0.05 | 2.6e-06 | 6.9 | -7.0 | 2.2e-12 | 0.78 | 0.40 | 0.57 | FALSE |