TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Waist Hip Ratio (WHR)
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chr21:38,835,811-40,373,763
Best TWAS P=2.33e-17 · Best GWAS P=1.48e-18 conditioned to 0.0113
38.8M
39M
39.2M
39.4M
39.6M
39.8M
40M
40.2M
40.4M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Testicular Germ Cell Tumors
DSCR10
0.07
0.03
blup
35
0.06
3.0e-03
-8.4
8.5
2.3e-17
0.92
0.01
0.75
TRUE
1
METSIM
Adipose
KCNJ15
0.05
0.03
lasso
5
0.02
6.8e-04
7.7
-8.0
9.8e-16
-0.86
0.20
0.78
FALSE
2
NTR
Blood
KCNJ15
0.06
0.09
lasso
4
0.09
7.0e-27
7.7
-7.8
8.0e-15
-0.88
0.87
0.13
FALSE
3
YFS
Blood
KCNJ15
0.22
0.29
enet
19
0.30
3.9e-100
7.7
-7.4
1.1e-13
-0.86
0.46
0.54
FALSE
5
The Cancer Genome Atlas
Thyroid Carcinoma
KCNJ15
0.09
0.05
blup
66
0.05
1.3e-05
-4.2
-5.7
1.2e-08
-0.45
0.17
0.12
FALSE