Best TWAS P=2.33e-17 · Best GWAS P=1.48e-18 conditioned to 0.0113
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | KCNJ15 | 0.05 | 0.03 | lasso | 5 | 0.02 | 6.8e-04 | 7.7 | -8.0 | 9.8e-16 | -0.86 | 0.20 | 0.78 | FALSE |
| 2 | NTR | Blood | KCNJ15 | 0.06 | 0.09 | lasso | 4 | 0.09 | 7.0e-27 | 7.7 | -7.8 | 8.0e-15 | -0.88 | 0.87 | 0.13 | FALSE |
| 3 | YFS | Blood | KCNJ15 | 0.22 | 0.29 | enet | 19 | 0.30 | 3.9e-100 | 7.7 | -7.4 | 1.1e-13 | -0.86 | 0.46 | 0.54 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | DSCR10 | 0.07 | 0.03 | blup | 35 | 0.06 | 3.0e-03 | -8.4 | 8.5 | 2.3e-17 | 0.92 | 0.01 | 0.75 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | KCNJ15 | 0.09 | 0.05 | blup | 66 | 0.05 | 1.3e-05 | -4.2 | -5.7 | 1.2e-08 | -0.45 | 0.17 | 0.12 | FALSE |