Best TWAS P=2.17e-08 · Best GWAS P=6.64e-11 conditioned to 0.000227
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | COL6A2 | 0.13 | 0.11 | lasso | 7 | 0.11 | 7.7e-14 | 5.9 | 5.6 | 2.2e-08 | 0.69 | 0.07 | 0.93 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | COL6A2 | 0.05 | 0.00 | blup | 75 | 0.01 | 1.9e-02 | 6.0 | 5.3 | 1.3e-07 | 0.67 | 0.01 | 0.40 | FALSE |