[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr20:61,989,111-62,912,463

Best TWAS P=4.17e-16 · Best GWAS P=2.69e-16 conditioned to 0.129

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	TCEA2	0.11	0.06	lasso	2	0.03	9.4e-04	4.9	5.1	2.8e-07	0.56	0.36	0.08	FALSE
2	GTEx	Adrenal Gland	OPRL1	0.48	0.29	enet	21	0.22	1.5e-08	-7.0	-7.8	6.7e-15	-0.78	0.06	0.94	FALSE
3	GTEx	Adrenal Gland	RGS19	0.32	0.20	lasso	8	0.21	5.8e-08	-7.0	-6.3	3.4e-10	-0.79	0.15	0.68	FALSE
4	GTEx	Artery Aorta	OPRL1	0.27	0.19	lasso	4	0.17	1.4e-09	-7.0	-7.0	1.8e-12	-0.80	0.34	0.66	FALSE
5	GTEx	Artery Aorta	TCEA2	0.09	0.04	lasso	3	0.03	1.3e-02	-7.0	6.7	2.3e-11	0.76	0.01	0.98	FALSE
6	GTEx	Artery Tibial	OPRL1	0.10	0.10	lasso	2	0.06	1.1e-05	-7.0	-7.3	2.3e-13	-0.88	0.06	0.94	FALSE
7	GTEx	Artery Tibial	RGS19	0.12	0.07	lasso	2	0.07	2.8e-06	7.6	-7.6	3.5e-14	-0.95	0.04	0.96	FALSE
8	GTEx	Brain Cerebellar Hemisphere	OPRL1	0.27	0.14	lasso	7	0.17	4.4e-05	-7.0	-6.7	1.8e-11	-0.77	0.02	0.75	FALSE
9	GTEx	Brain Cerebellum	RGS19	0.28	0.22	lasso	4	0.18	7.2e-06	-7.0	-6.9	5.4e-12	-0.81	0.02	0.90	FALSE
10	GTEx	Cells Transformed fibroblasts	OPRL1	0.25	0.07	enet	13	0.12	5.5e-09	5.4	-6.7	1.7e-11	-0.72	0.50	0.50	FALSE
11	GTEx	Cells Transformed fibroblasts	RGS19	0.37	0.28	lasso	8	0.29	3.2e-22	7.6	-7.7	1.2e-14	-0.93	0.01	0.99	FALSE
12	GTEx	Colon Sigmoid	RGS19	0.27	0.07	enet	33	0.09	3.8e-04	-5.5	-5.3	9.7e-08	-0.61	0.04	0.93	FALSE
13	GTEx	Esophagus Mucosa	RGS19	0.43	0.28	enet	17	0.34	7.9e-24	-7.0	-7.7	1.3e-14	-0.91	0.00	1.00	FALSE
14	GTEx	Esophagus Muscularis	OPRL1	0.17	0.14	lasso	1	0.13	4.7e-08	-7.0	-7.0	1.9e-12	-0.84	0.08	0.92	FALSE
15	GTEx	Esophagus Muscularis	RGS19	0.22	0.10	lasso	4	0.10	1.6e-06	-7.0	-6.9	5.2e-12	-0.80	0.18	0.81	FALSE
16	GTEx	Muscle Skeletal	RGS19	0.26	0.16	lasso	4	0.16	5.1e-15	7.6	-7.2	6.0e-13	-0.94	0.07	0.93	FALSE
17	GTEx	Nerve Tibial	OPRL1	0.20	0.15	lasso	3	0.14	3.3e-10	-7.0	-6.8	1.2e-11	-0.82	0.44	0.56	FALSE
18	GTEx	Pancreas	OPRL1	0.39	0.27	lasso	5	0.32	6.9e-14	-7.0	-7.4	1.0e-13	-0.90	0.05	0.95	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	RGS19	0.51	0.28	enet	28	0.32	4.3e-18	-7.0	-7.2	8.7e-13	-0.80	0.01	0.99	FALSE
20	GTEx	Skin Sun Exposed Lower leg	OPRL1	0.14	0.10	lasso	6	0.11	4.4e-09	7.6	-8.0	1.3e-15	-0.93	0.01	0.99	FALSE
21	GTEx	Skin Sun Exposed Lower leg	RGS19	0.42	0.26	lasso	6	0.33	4.6e-28	-7.0	-8.1	4.2e-16	-0.95	0.00	1.00	TRUE
22	GTEx	Stomach	OPRL1	0.36	0.23	enet	16	0.19	1.3e-09	-7.0	-7.1	9.7e-13	-0.75	0.30	0.70	FALSE
23	GTEx	Stomach	RGS19	0.18	0.25	lasso	2	0.25	2.2e-12	-7.0	-7.1	1.4e-12	-0.84	0.79	0.20	FALSE
24	GTEx	Thyroid	RGS19	0.23	0.14	enet	11	0.19	3.3e-14	7.6	-7.3	2.1e-13	-0.92	0.00	1.00	FALSE
25	GTEx	Vagina	RGS19	0.39	0.08	lasso	8	0.03	7.5e-02	7.6	-7.0	3.2e-12	-0.91	0.01	0.84	FALSE
26	GTEx	Whole Blood	OPRL1	0.09	0.06	enet	8	0.07	4.3e-07	8.2	7.9	2.6e-15	0.92	0.00	1.00	FALSE
27	NTR	Blood	OPRL1	0.07	0.02	bslmm	309	0.03	8.5e-10	8.2	5.2	1.5e-07	0.53	0.00	1.00	FALSE
28	ROSMAP	Brain Pre-frontal Cortex	C20orf201	0.10	0.09	enet	9	0.10	9.9e-13	-5.3	6.6	5.7e-11	0.68	0.23	0.77	FALSE
29	YFS	Blood	OPRL1	0.07	0.07	lasso	5	0.09	5.0e-27	-7.0	7.3	2.9e-13	0.82	0.38	0.62	FALSE
30	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RGS19	0.04	0.04	blup	48	0.03	1.1e-03	-7.0	-6.3	3.9e-10	-0.71	0.01	0.85	FALSE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	C20orf201	0.03	0.01	lasso	4	0.01	2.3e-03	-5.3	5.2	1.9e-07	0.61	0.31	0.17	FALSE
32	The Cancer Genome Atlas	Colon Adenocarcinoma	RGS19	0.09	0.04	enet	4	0.04	2.8e-03	-5.1	-5.4	8.3e-08	-0.59	0.06	0.75	FALSE
33	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RGS19	0.06	0.06	blup	47	0.05	1.4e-06	-7.0	-6.6	5.2e-11	-0.80	0.00	1.00	FALSE
34	The Cancer Genome Atlas	Brain Lower Grade Glioma	OPRL1	0.03	0.02	lasso	1	0.01	3.5e-02	-7.0	-7.0	1.9e-12	-0.84	0.01	0.85	FALSE
35	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RGS19	0.05	0.02	blup	48	0.02	1.1e-03	4.4	-7.2	4.6e-13	-0.75	0.01	0.97	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	OPRL1	0.07	0.08	lasso	4	0.08	7.8e-09	-5.3	-6.0	2.6e-09	-0.68	0.80	0.19	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	RGS19	0.07	0.05	blup	48	0.07	1.1e-07	-5.3	-6.5	6.3e-11	-0.79	0.04	0.96	FALSE
38	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RGS19	0.18	0.08	enet	10	0.07	2.2e-03	4.4	-5.8	6.8e-09	-0.61	0.13	0.26	FALSE