Best TWAS P=7.49e-13 · Best GWAS P=1.32e-13 conditioned to 0.172
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | LYG1 | 0.07 | 0.05 | enet | 8 | 0.04 | 0.0018 | -3.8 | -5.2 | 2.0e-07 | -0.07 | 0.51 | 0.04 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | AFF3 | 0.08 | 0.02 | lasso | 4 | 0.02 | 0.0035 | 6.8 | 7.2 | 7.5e-13 | 0.90 | 0.04 | 0.90 | TRUE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | AFF3 | 0.11 | 0.01 | blup | 239 | 0.03 | 0.0162 | 5.5 | -6.3 | 3.9e-10 | -0.43 | 0.13 | 0.39 | FALSE |