Best TWAS P=8.58e-26 · Best GWAS P=7.06e-70 conditioned to 3.24e-46
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | ADAMTS9 | 0.16 | 0.11 | enet | 12 | 0.12 | 3.9e-09 | 4.8 | 6.5 | 5.8e-11 | -0.22 | 0.99 | 0.00 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | ADAMTS9-AS2 | 0.12 | 0.00 | blup | 844 | 0.06 | 2.1e-08 | -17.5 | -10.5 | 8.6e-26 | 0.53 | 0.01 | 0.99 | TRUE |