Best TWAS P=7.78e-12 · Best GWAS P=2.24e-11 conditioned to 5.96e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | CMSS1 | 0.12 | 0.01 | enet | 15 | 0.06 | 2.8e-04 | -3.1 | 6.8 | 7.8e-12 | 0.45 | 0.06 | 0.78 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | CMSS1 | 0.08 | 0.02 | enet | 17 | 0.05 | 1.5e-04 | -4.0 | 5.2 | 1.8e-07 | 0.45 | 0.57 | 0.25 | FALSE |
| 3 | GTEx | Muscle Skeletal | TFG | 0.09 | 0.07 | enet | 13 | 0.07 | 2.1e-07 | 5.2 | 5.7 | 1.3e-08 | -0.08 | 0.01 | 0.99 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | TBC1D23 | 0.06 | 0.04 | lasso | 4 | 0.05 | 2.4e-05 | 5.3 | 6.0 | 1.4e-09 | 0.82 | 0.07 | 0.90 | FALSE |
| 5 | GTEx | Stomach | TBC1D23 | 0.08 | 0.02 | lasso | 3 | 0.02 | 3.5e-02 | 6.3 | 6.3 | 3.9e-10 | 0.55 | 0.11 | 0.35 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C3orf26 | 0.03 | 0.02 | blup | 163 | 0.02 | 5.8e-06 | -4.0 | 5.5 | 4.7e-08 | 0.41 | 0.52 | 0.44 | FALSE |
| 7 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | C3orf26 | 0.10 | 0.02 | blup | 163 | 0.05 | 4.6e-03 | 5.6 | 5.3 | 1.3e-07 | 0.22 | 0.15 | 0.28 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | C3orf26 | 0.10 | 0.03 | blup | 165 | 0.04 | 9.3e-05 | -3.9 | 6.4 | 1.6e-10 | 0.52 | 0.39 | 0.27 | FALSE |