[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr4:119,437,972-121,242,474

Best TWAS P=9.73e-11 · Best GWAS P=6.66e-09 conditioned to 0.651

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex USP53 0.16 0.13 lasso 11 0.20 3.5e-23 5.8 5.3 1.1e-07 0.84 0.01 0.99 FALSE
2 GTEx Thyroid PDE5A 0.09 0.04 lasso 3 0.04 6.9e-04 4.7 5.2 2.3e-07 0.86 0.06 0.77 FALSE
3 GTEx Whole Blood USP53 0.09 0.05 enet 11 0.06 3.1e-06 5.5 5.6 1.7e-08 0.96 0.02 0.98 FALSE
4 NTR Blood USP53 0.10 0.10 bslmm 482 0.11 2.6e-34 5.5 5.7 9.8e-09 0.89 0.02 0.98 FALSE
5 YFS Blood USP53 0.06 0.05 bslmm 479 0.06 8.1e-20 5.5 6.5 9.7e-11 0.86 0.01 0.99 TRUE
6 The Cancer Genome Atlas Brain Lower Grade Glioma USP53 0.25 0.05 lasso 5 0.08 6.5e-09 -3.2 5.5 4.8e-08 0.75 0.02 0.98 FALSE
7 The Cancer Genome Atlas Thyroid Carcinoma USP53 0.11 0.03 blup 88 0.07 5.8e-07 5.5 6.0 2.2e-09 0.91 0.01 0.99 FALSE