[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr4:121,892,436-124,538,705

Best TWAS P=4.89e-15 · Best GWAS P=3.26e-13 conditioned to 0.000755

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	BBS12	0.06	0.06	enet	9	0.06	8.7e-08	-5.4	-5.7	1.5e-08	0.12	0.99	0.01	FALSE
2	GTEx	Adipose Subcutaneous	ANXA5	0.25	0.16	lasso	5	0.19	9.9e-16	-5.6	5.7	1.5e-08	-0.03	0.05	0.95	FALSE
3	GTEx	Adrenal Gland	ANXA5	0.23	0.16	lasso	4	0.15	5.3e-06	-6.7	6.4	1.4e-10	-0.01	0.00	1.00	TRUE
4	GTEx	Artery Aorta	ANXA5	0.23	0.21	lasso	3	0.21	1.3e-11	-5.6	5.8	6.5e-09	0.01	0.42	0.58	FALSE
5	GTEx	Artery Tibial	FGF2	0.18	0.05	lasso	3	0.02	1.3e-02	-7.1	-7.2	5.4e-13	0.33	0.01	0.92	FALSE
6	GTEx	Artery Tibial	ANXA5	0.32	0.22	lasso	8	0.20	1.2e-15	-5.6	6.0	2.7e-09	0.00	0.26	0.74	FALSE
7	GTEx	Brain Nucleus accumbens basal ganglia	ANXA5	0.46	0.26	lasso	7	0.23	9.9e-07	-5.6	5.7	1.1e-08	0.01	0.16	0.75	FALSE
8	GTEx	Breast Mammary Tissue (Female)	FGF2	0.20	0.00	enet	4	-0.01	7.9e-01	4.2	-5.5	4.1e-08	0.20	0.06	0.31	FALSE
9	GTEx	Breast Mammary Tissue (Female)	NUDT6	0.30	-0.01	enet	30	0.00	2.6e-01	-3.2	-7.8	4.9e-15	0.57	0.03	0.38	TRUE
10	GTEx	Cells EBV-transformed lymphocytes	ANXA5	0.45	0.06	enet	26	0.23	3.7e-08	-5.6	6.1	8.1e-10	-0.06	0.01	0.97	FALSE
11	GTEx	Nerve Tibial	ANXA5	0.16	0.07	lasso	4	0.09	1.1e-06	5.4	5.3	1.4e-07	-0.04	0.06	0.93	FALSE
12	GTEx	Pituitary	ANXA5	0.35	0.36	lasso	4	0.27	1.7e-07	-5.6	5.6	2.6e-08	0.01	0.09	0.90	FALSE
13	GTEx	Spleen	ANXA5	0.42	0.28	lasso	6	0.23	1.7e-06	-5.6	5.2	1.9e-07	0.00	0.24	0.52	FALSE
14	GTEx	Testis	ANXA5	0.43	0.33	lasso	3	0.32	6.3e-15	-5.6	5.6	2.2e-08	0.01	0.13	0.87	FALSE
15	GTEx	Thyroid	ANXA5	0.29	0.18	lasso	7	0.18	1.6e-13	-5.6	5.9	2.9e-09	0.00	0.07	0.93	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	ANXA5	0.48	0.47	lasso	9	0.49	5.3e-72	-5.6	5.2	2.2e-07	0.01	0.43	0.57	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	BBS12	0.01	0.02	lasso	2	0.01	6.6e-04	-5.2	-5.2	1.6e-07	0.12	0.03	0.91	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	CETN4P	0.06	0.06	lasso	2	0.06	2.0e-11	-5.2	-5.2	1.7e-07	0.12	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Glioblastoma Multiforme	ANXA5	0.29	0.07	blup	73	0.12	1.4e-04	-5.6	5.3	1.4e-07	0.01	0.01	0.93	FALSE
20	The Cancer Genome Atlas	Glioblastoma Multiforme	CETN4P	0.12	0.08	blup	39	0.11	2.8e-04	-4.4	-5.6	1.6e-08	0.14	0.01	0.90	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ANXA5	0.05	0.03	blup	75	0.03	4.7e-04	-6.7	6.2	6.8e-10	0.01	0.00	0.99	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CETN4P	0.08	0.10	lasso	2	0.10	4.8e-11	-5.2	-5.2	1.5e-07	0.12	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FGF2	0.06	0.04	blup	65	0.05	4.4e-06	-3.4	-6.3	3.4e-10	0.78	0.02	0.97	FALSE
24	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ANXA5	0.22	0.05	lasso	5	0.13	1.1e-07	3.2	5.5	3.5e-08	0.00	0.01	0.98	FALSE
25	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CETN4P	0.11	0.10	blup	39	0.10	1.5e-06	-5.3	-5.6	1.9e-08	0.14	0.01	0.99	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	BBS12	0.06	0.06	lasso	5	0.06	4.0e-07	-5.1	-5.2	2.0e-07	0.09	0.04	0.96	FALSE
27	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CETN4P	0.14	0.09	lasso	2	0.05	1.4e-03	-5.3	-5.3	1.2e-07	0.12	0.01	0.95	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	CETN4P	0.04	0.04	blup	39	0.05	1.2e-06	-5.4	-5.7	1.5e-08	0.14	0.01	0.99	FALSE
29	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ANXA5	0.07	0.04	blup	75	0.04	5.2e-05	-5.6	5.3	9.7e-08	0.01	0.02	0.98	FALSE
30	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ANXA5	0.08	0.06	lasso	3	0.06	7.8e-05	-5.6	6.0	1.6e-09	0.00	0.05	0.83	FALSE
31	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CETN4P	0.07	0.12	lasso	1	0.11	2.6e-05	-5.4	-5.4	6.4e-08	0.06	0.01	0.96	FALSE
32	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ANXA5	0.23	0.24	lasso	7	0.22	2.7e-09	-5.8	6.1	1.4e-09	0.01	0.18	0.82	FALSE
33	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CETN4P	0.17	0.14	lasso	4	0.15	1.8e-06	-5.3	-5.4	5.6e-08	0.11	0.01	0.99	FALSE
34	The Cancer Genome Atlas	Prostate Adenocarcinoma	ANXA5	0.05	0.03	enet	7	0.04	3.3e-05	-6.7	6.4	1.7e-10	0.01	0.00	1.00	FALSE
35	The Cancer Genome Atlas	Prostate Adenocarcinoma	CETN4P	0.05	0.04	lasso	3	0.04	5.9e-05	-5.3	-5.3	1.2e-07	0.12	0.01	0.98	FALSE
36	The Cancer Genome Atlas	Soft Tissue Sarcoma	ANXA5	0.06	0.03	lasso	3	0.03	9.8e-03	-5.6	6.0	1.5e-09	0.00	0.02	0.84	FALSE
37	The Cancer Genome Atlas	Testicular Germ Cell Tumors	BBS12	0.08	0.02	blup	42	0.04	1.1e-02	-6.1	-5.3	1.0e-07	0.12	0.01	0.77	FALSE
38	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CETN4P	0.10	0.05	blup	39	0.07	2.5e-03	-5.3	-5.5	3.6e-08	0.15	0.01	0.85	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	CETN4P	0.10	0.10	blup	39	0.11	1.0e-10	-5.4	-5.7	9.0e-09	0.11	0.00	1.00	FALSE