Best TWAS P=2.23e-08 · Best GWAS P=5.16e-08 conditioned to 0.607
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | YTHDC2 | 0.23 | 0.03 | enet | 21 | 0.05 | 7.3e-04 | 5.0 | 5.2 | 1.7e-07 | 0.86 | 0.05 | 0.94 | FALSE |
| 2 | GTEx | Artery Tibial | YTHDC2 | 0.17 | 0.09 | lasso | 9 | 0.08 | 3.9e-07 | 5.4 | 5.6 | 2.2e-08 | 0.94 | 0.02 | 0.98 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | YTHDC2 | 0.02 | 0.01 | blup | 86 | 0.02 | 2.7e-03 | 4.7 | 5.2 | 2.5e-07 | 0.94 | 0.02 | 0.87 | FALSE |