Best TWAS P=3.05e-22 · Best GWAS P=9.51e-17 conditioned to 0.857
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | TNFAIP8 | 0.21 | 0.12 | lasso | 6 | 0.14 | 8.2e-11 | 7.9 | -9.7 | 3.0e-22 | -0.87 | 0.00 | 1.00 | TRUE |
2 | GTEx | Uterus | DMXL1 | 0.40 | -0.01 | lasso | 8 | 0.02 | 1.1e-01 | -1.7 | -5.5 | 5.2e-08 | -0.32 | 0.06 | 0.11 | FALSE |