[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr5:101,392,473-103,244,640

Best TWAS P=3.73e-16 · Best GWAS P=5.99e-16 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PPIP5K2	0.07	0.10	lasso	3	0.12	1.2e-09	-7.46	7.4	1.5e-13	-0.90	0.13	0.87	FALSE
2	GTEx	Adrenal Gland	PPIP5K2	0.16	0.17	lasso	5	0.18	5.9e-07	-7.33	7.5	4.9e-14	-0.94	0.07	0.93	FALSE
3	GTEx	Artery Aorta	PPIP5K2	0.08	0.07	lasso	3	0.07	1.2e-04	-7.34	7.4	1.3e-13	-0.92	0.18	0.80	FALSE
4	GTEx	Artery Aorta	PAM	0.06	0.03	lasso	6	0.02	2.5e-02	-6.34	-7.2	6.4e-13	0.39	0.21	0.12	TRUE
5	GTEx	Artery Tibial	PPIP5K2	0.07	0.04	enet	22	0.05	1.4e-04	-7.88	7.1	1.6e-12	-0.78	0.04	0.96	FALSE
6	GTEx	Brain Cerebellar Hemisphere	PAM	0.27	0.10	lasso	4	0.13	2.7e-04	-6.44	-7.9	2.8e-15	0.69	0.19	0.73	FALSE
7	GTEx	Brain Cerebellum	PAM	0.26	0.17	lasso	4	0.15	3.5e-05	-6.37	-6.6	4.9e-11	0.44	0.37	0.49	FALSE
8	GTEx	Brain Nucleus accumbens basal ganglia	PPIP5K2	0.19	0.06	enet	22	0.05	1.7e-02	-6.92	6.3	3.1e-10	-0.87	0.09	0.67	FALSE
9	GTEx	Breast Mammary Tissue	PPIP5K2	0.11	0.10	lasso	5	0.04	2.7e-03	-8.09	8.1	6.0e-16	-0.98	0.01	0.98	FALSE
10	GTEx	Breast Mammary Tissue (Female)	PPIP5K2	0.09	0.01	lasso	7	0.00	2.9e-01	-7.21	7.8	8.7e-15	-0.93	0.06	0.71	FALSE
11	GTEx	Cells EBV-transformed lymphocytes	PPIP5K2	0.37	0.32	enet	22	0.37	6.6e-13	-6.99	-7.3	2.0e-13	0.84	0.70	0.30	FALSE
12	GTEx	Colon Sigmoid	PPIP5K2	0.14	0.00	enet	17	0.04	1.9e-02	-7.57	7.4	1.8e-13	-0.87	0.07	0.87	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	PPIP5K2	0.14	0.09	lasso	2	0.03	3.0e-02	-8.09	7.6	2.1e-14	-0.97	0.02	0.93	FALSE
14	GTEx	Esophagus Muscularis	PPIP5K2	0.05	0.02	enet	14	0.03	9.8e-03	-7.56	7.7	1.9e-14	-0.94	0.17	0.78	FALSE
15	GTEx	Muscle Skeletal	GIN1	0.04	0.01	lasso	3	0.00	1.5e-01	-5.04	-6.9	6.6e-12	0.83	0.05	0.82	FALSE
16	GTEx	Nerve Tibial	PPIP5K2	0.11	0.13	lasso	12	0.11	6.5e-08	-7.51	7.5	5.7e-14	-0.91	0.21	0.79	FALSE
17	GTEx	Pituitary	PPIP5K2	0.15	0.10	enet	13	0.11	1.2e-03	-7.51	7.6	3.9e-14	-0.89	0.13	0.55	FALSE
18	GTEx	Skin Sun Exposed Lower leg	PAM	0.04	0.00	lasso	4	0.04	2.3e-04	-5.64	-7.5	9.6e-14	0.82	0.09	0.54	FALSE
19	GTEx	Small Intestine Terminal Ileum	PPIP5K2	0.33	-0.01	enet	25	0.00	3.0e-01	-0.96	5.3	1.3e-07	-0.55	0.06	0.18	FALSE
20	GTEx	Spleen	PPIP5K2	0.18	0.19	enet	15	0.19	1.1e-05	-7.17	-7.0	2.1e-12	0.88	0.24	0.72	FALSE
21	GTEx	Stomach	PPIP5K2	0.05	0.04	lasso	2	0.03	8.7e-03	-6.99	7.1	1.6e-12	-0.86	0.12	0.61	FALSE
22	GTEx	Thyroid	PAM	0.07	0.08	lasso	4	0.07	5.5e-06	-6.51	6.2	5.3e-10	-0.60	0.95	0.01	FALSE
23	GTEx	Whole Blood	PPIP5K2	0.14	0.06	lasso	6	0.08	1.6e-07	-7.27	6.4	1.4e-10	-0.81	0.11	0.89	FALSE
24	GTEx	Whole Blood	PAM	0.20	0.28	lasso	9	0.27	1.0e-24	-6.40	-6.4	1.3e-10	0.71	1.00	0.00	FALSE
25	METSIM	Adipose	PAM	0.04	0.02	lasso	2	0.02	2.9e-04	-6.60	-5.9	4.0e-09	0.70	0.60	0.10	FALSE
26	METSIM	Adipose	PPIP5K2	0.05	0.07	blup	347	0.07	6.3e-11	-7.55	6.7	2.1e-11	-0.86	0.11	0.89	FALSE
27	NTR	Blood	PAM	0.26	0.29	lasso	1	0.29	2.6e-95	-6.42	-6.4	1.4e-10	0.70	1.00	0.00	FALSE
28	NTR	Blood	PPIP5K2	0.03	0.04	enet	10	0.04	5.3e-14	-7.18	7.1	1.5e-12	-0.86	0.60	0.40	FALSE
29	ROSMAP	Brain Pre-frontal Cortex	GIN1	0.02	0.01	blup	253	0.01	2.3e-02	-7.19	-7.2	4.8e-13	0.87	0.07	0.51	FALSE
30	YFS	Blood	GIN1	0.02	0.04	lasso	7	0.05	5.1e-17	-6.71	-7.1	1.3e-12	0.88	0.35	0.65	FALSE
31	YFS	Blood	PAM	0.64	0.68	enet	68	0.72	0.0e+00	-6.42	-5.6	2.4e-08	0.57	1.00	0.00	FALSE
32	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PPIP5K2	0.03	0.03	lasso	3	0.03	1.4e-03	-7.32	-7.3	2.8e-13	0.88	0.01	0.88	FALSE
33	The Cancer Genome Atlas	Breast Invasive Carcinoma	GIN1	0.01	0.01	blup	21	0.01	1.7e-03	-7.32	-7.3	2.4e-13	0.89	0.02	0.82	FALSE
34	The Cancer Genome Atlas	Breast Invasive Carcinoma	PPIP5K2	0.01	0.01	blup	17	0.01	9.3e-04	-7.27	-7.3	2.3e-13	0.88	0.01	0.86	FALSE
35	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	GIN1	0.11	0.03	blup	21	0.05	1.7e-03	-7.55	-7.3	3.6e-13	0.90	0.01	0.80	FALSE
36	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PPIP5K2	0.16	0.03	lasso	3	0.05	2.6e-03	-6.67	-6.8	1.0e-11	0.73	0.01	0.64	FALSE
37	The Cancer Genome Atlas	Colon Adenocarcinoma	PPIP5K2	0.05	0.03	blup	17	0.03	7.1e-03	-7.32	-6.9	4.9e-12	0.86	0.01	0.78	FALSE
38	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PPIP5K2	0.04	0.04	blup	16	0.05	4.1e-06	-7.19	-7.0	2.4e-12	0.88	0.01	0.99	FALSE
39	The Cancer Genome Atlas	Brain Lower Grade Glioma	GIN1	0.08	0.08	lasso	5	0.09	3.1e-10	-7.27	-6.6	3.8e-11	0.81	0.04	0.96	FALSE
40	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PPIP5K2	0.04	0.03	blup	17	0.03	1.1e-02	-7.32	-7.0	2.5e-12	0.88	0.01	0.81	FALSE
41	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PAM	0.09	0.03	lasso	2	0.03	3.2e-02	-8.09	-8.2	3.7e-16	1.00	0.01	0.74	TRUE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	GIN1	0.03	0.03	blup	22	0.03	5.5e-04	-6.92	-7.0	2.4e-12	0.87	0.03	0.94	FALSE
43	The Cancer Genome Atlas	Soft Tissue Sarcoma	GIN1	0.03	0.02	blup	21	0.03	7.9e-03	-7.27	-7.3	3.6e-13	0.89	0.01	0.60	FALSE
44	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PPIP5K2	0.26	0.21	lasso	7	0.23	1.2e-08	-7.32	-6.5	7.1e-11	0.85	0.01	0.99	FALSE
45	The Cancer Genome Atlas	Thyroid Carcinoma	GIN1	0.06	0.07	lasso	3	0.06	1.6e-06	-7.27	-7.2	5.3e-13	0.89	0.01	0.99	FALSE