Best TWAS P=8.08e-11 · Best GWAS P=5.89e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | REEP2 | 0.12 | 0.02 | lasso | 6 | 0.02 | 3.0e-02 | 6.5 | 5.9 | 4.2e-09 | 0.94 | 0.01 | 0.97 | FALSE |
| 2 | GTEx | Esophagus Muscularis | REEP2 | 0.13 | 0.11 | enet | 13 | 0.12 | 1.2e-07 | 6.5 | 5.8 | 4.9e-09 | 0.93 | 0.00 | 0.99 | FALSE |
| 3 | GTEx | Heart Atrial Appendage | REEP2 | 0.24 | 0.15 | lasso | 6 | 0.13 | 2.0e-06 | 6.5 | 6.5 | 8.1e-11 | 1.00 | 0.00 | 1.00 | TRUE |
| 4 | GTEx | Nerve Tibial | REEP2 | 0.16 | 0.08 | lasso | 11 | 0.10 | 2.5e-07 | 6.5 | 6.2 | 4.8e-10 | 0.92 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | EGR1 | 0.02 | 0.01 | blup | 41 | 0.02 | 1.9e-03 | 6.5 | 6.5 | 8.6e-11 | 0.93 | 0.00 | 0.96 | FALSE |