Best TWAS P=1.96e-09 · Best GWAS P=2.45e-10 conditioned to 0.000649
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ABLIM3 | 0.07 | 0.07 | lasso | 2 | 0.05 | 7.8e-05 | 4.9 | 5.5 | 3.4e-08 | 0.89 | 0.03 | 0.97 | TRUE |
| 2 | GTEx | Whole Blood | NDST1 | 0.17 | 0.12 | enet | 10 | 0.13 | 9.7e-12 | 5.9 | -6.0 | 2.0e-09 | 0.02 | 0.01 | 0.99 | TRUE |
| 3 | METSIM | Adipose | NDST1 | 0.10 | 0.05 | bslmm | 549 | 0.05 | 3.3e-08 | 5.7 | -5.4 | 6.5e-08 | 0.00 | 0.01 | 0.99 | FALSE |
| 4 | NTR | Blood | NDST1 | 0.04 | 0.02 | lasso | 3 | 0.01 | 4.8e-05 | 5.7 | -5.2 | 2.4e-07 | -0.02 | 0.01 | 0.98 | FALSE |
| 5 | YFS | Blood | NDST1 | 0.34 | 0.27 | lasso | 8 | 0.29 | 2.0e-94 | 5.9 | -5.9 | 3.0e-09 | -0.01 | 0.00 | 1.00 | FALSE |