Hub : Genes

ABLIM3

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1500	0.0340	2.9e-11	0.147	0.114	0.159	0.138	0.151	1.8e-17	9.8e-14	7.6e-19	1.8e-16	5.9e-18
2	GTEx	Adipose Subcutaneous	0.0690	0.0280	3.8e-03	0.068	NA	0.033	NA	0.048	3.3e-06	NA	9.2e-04	NA	7.8e-05
3	GTEx	Brain Cerebellar Hemisphere	0.4190	0.0980	3.6e-05	0.043	NA	0.049	NA	0.011	3.0e-02	NA	2.2e-02	NA	1.6e-01
4	GTEx	Brain Cerebellum	0.5050	0.0900	1.3e-07	0.344	NA	0.350	NA	0.395	5.6e-11	NA	3.6e-11	NA	9.4e-13
5	GTEx	Brain Frontal Cortex BA9	0.2416	0.0907	7.8e-03	0.056	NA	-0.005	NA	0.068	1.3e-02	NA	4.7e-01	NA	7.3e-03
6	GTEx	Esophagus Mucosa	0.2430	0.0610	8.4e-07	0.256	NA	0.244	NA	0.246	3.0e-17	NA	2.3e-16	NA	1.5e-16
7	GTEx	Pituitary	0.2720	0.1030	2.2e-03	0.024	NA	0.037	NA	0.075	8.1e-02	NA	4.3e-02	NA	6.3e-03
8	ROSMAP	Brain Pre-frontal Cortex	0.3200	0.0451	0.0e+00	0.342	0.300	0.313	0.330	0.328	1.9e-45	4.0e-39	5.7e-41	1.1e-43	2.9e-43
9	YFS	Blood	0.0254	0.0097	4.9e-04	0.010	0.017	0.007	0.016	0.009	2.1e-04	2.4e-06	1.3e-03	3.9e-06	4.5e-04
10	TCGA	Breast Invasive Carcinoma	0.0217	0.0104	2.8e-03	0.015	0.012	0.013	NA	0.013	3.3e-04	1.3e-03	7.7e-04	NA	7.3e-04
11	TCGA	Glioblastoma Multiforme	0.2500	0.1210	3.2e-03	0.015	0.109	0.074	NA	0.078	1.1e-01	3.4e-04	2.9e-03	NA	2.3e-03
12	TCGA	Head and Neck Squamous Cell Carcinoma	0.0916	0.0285	1.9e-08	0.110	0.078	0.093	NA	0.100	2.6e-12	4.4e-09	1.3e-10	NA	2.4e-11
13	TCGA	Lung Squamous Cell Carcinoma	0.0750	0.0295	1.0e-04	0.041	0.039	0.048	NA	0.046	1.7e-05	2.7e-05	3.3e-06	NA	5.4e-06
14	TCGA	Ovarian Serous Cystadenocarcinoma	0.0900	0.0400	1.9e-03	0.020	0.044	0.019	NA	0.017	1.5e-02	5.5e-04	1.7e-02	NA	2.2e-02
15	TCGA	Prostate Adenocarcinoma	0.1234	0.0342	5.9e-13	0.158	0.149	0.164	NA	0.159	3.2e-16	2.4e-15	8.5e-17	NA	2.2e-16

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	0.6	1.0	3.9	-0.2	0.0	0.6	-0.3	0.1	-1.2	-2.0	0.0	-0.8	-1.3	-0.6	-1.3	-0.0	-1.5	-1.4
Bipolar Disorder or Schizophrenia	0.7	1.8	4.7	-1.5	0.6	0.5	-1.1	-0.1	-1.9	-1.7	-1.3	-0.5	-2.0	-0.8	-1.9	-0.7	-0.9	-2.2
Depressed Affect (Nagel 2018)	1.1	2.2	4.7	-2.1	1.0	-2.2	-1.8	-1.3	-1.1	-2.0	-1.4	0.8	-1.4	-1.5	-1.2	-0.5	-1.2	-1.7
Depression (Nagel 2018)	3.8	5.7	16.7	-2.6	2.4	-2.4	-2.6	-1.8	-2.1	-2.0	-1.6	0.5	-2.9	-4.1	-2.2	-2.0	-2.1	-3.0
Intelligence (Savage-Jansen 2018)	0.6	1.7	5.8	0.8	-0.7	1.4	1.1	2.4	-1.1	-0.8	1.1	-0.5	-1.3	0.8	-1.3	-1.1	-2.2	-1.5
Neuroticism (Nagel 2018)	0.2	0.6	3.3	-1.2	0.2	-0.3	-0.9	-0.0	-0.2	-1.8	-1.0	-0.2	-0.2	-1.2	-0.2	-0.0	-0.4	-0.5
Schizophrenia (2018)	0.6	1.2	3.3	-1.8	0.8	0.1	-1.1	-0.2	-1.4	-0.6	-1.8	-0.1	-1.5	-0.6	-1.5	-0.8	0.0	-1.6
Schizophrenia vs Biploar Disorder	0.4	0.5	2.8	0.3	1.7	-0.6	-0.1	-1.3	0.5	0.2	-0.4	0.9	-0.7	-0.1	0.7	0.3	0.9	-0.3
Worry (Nagel 2018)	0.4	0.9	2.0	-0.4	-0.1	0.1	-0.6	1.0	1.2	-0.4	-1.0	0.5	1.3	-0.4	1.3	1.2	1.4	1.4
Alzheimer’s Disease (in mother)	1.2	1.4	3.5	1.9	-1.7	0.3	1.1	1.3	0.9	0.6	1.7	-0.8	1.1	1.6	1.0	0.7	0.4	1.2
Alzheimer’s Disease (in father)	0.4	0.4	1.4	-0.1	0.3	-0.7	0.2	0.6	-1.1	-0.2	-0.4	0.1	-1.2	0.1	-0.9	-0.4	-0.3	-1.1
Alzheimer’s Disease (including proxy)	1.7	2.5	7.0	2.6	-2.0	0.8	2.3	2.5	0.6	0.9	2.3	-1.3	0.8	2.1	0.7	0.5	-0.0	0.9
Crohns Disease (2017)	0.5	1.2	3.8	-0.3	0.8	-0.1	-0.9	-1.0	-1.2	-0.6	-0.1	-0.9	-1.9	-1.2	-1.2	-0.9	-1.1	-1.8
Irritable Bowel Disease (IBD)	0.3	0.8	3.1	0.5	0.2	1.4	0.5	-0.4	-1.0	0.4	1.0	-1.8	-1.1	-0.3	-1.1	-0.8	-0.5	-1.1
Ulcerative Colitis (UC)	0.7	1.2	4.1	1.1	-0.2	2.0	1.3	-0.1	-1.0	0.7	1.8	-1.9	-0.6	0.8	-1.1	-0.6	-0.1	-0.7
Major Depression (MDD)	0.4	0.5	2.1	-0.7	0.6	-1.4	-0.3	-1.0	0.0	-1.1	-0.6	-0.5	-0.1	-1.0	-0.1	0.3	-0.5	-0.1
Reaction Time	0.2	0.4	1.6	0.1	-1.3	-1.0	-0.0	-0.9	0.8	-0.4	0.2	-0.6	-0.0	0.6	0.7	0.2	-0.6	-0.1
Verbal and Numeric Reasoning (VNR)	0.7	1.6	5.2	-0.3	-0.1	0.2	0.9	0.6	-1.8	-0.9	0.5	-0.2	-2.0	0.5	-2.0	-1.3	-1.9	-2.3
Breast Cancer	2.1	5.1	9.4	-2.1	0.6	-2.8	-2.4	-0.0	-2.5	-1.4	-1.8	2.7	-2.8	-1.8	-2.6	-1.7	-2.9	-3.1
Ovarian Cancer	0.4	0.5	1.8	-0.8	-0.3	-0.5	0.1	0.4	0.3	1.1	-0.6	-0.8	0.8	0.0	0.4	1.3	0.9	0.7
Prostate Cancer	0.3	0.4	2.1	0.0	-0.4	0.6	0.3	0.8	-0.4	-1.4	0.3	-1.3	-0.3	0.5	-0.4	-0.6	-0.2	-0.4
Age at First Birth	1.1	1.5	4.7	0.2	0.1	1.5	0.7	0.1	-2.2	-1.8	0.6	0.2	-1.8	1.1	-2.1	0.0	-0.1	-1.8
Bipolar Disorder (2011)	0.5	0.5	4.0	-1.0	0.0	-0.1	-0.5	0.5	-0.5	-2.0	-1.0	-0.2	-0.2	0.9	-0.4	0.4	0.2	-0.3
Body Mass Index (BMI) (2010)	1.7	2.3	6.2	2.1	-2.5	0.4	2.2	2.3	0.9	-0.3	2.1	-1.1	1.1	2.1	0.6	-0.6	-0.7	0.9
Coronary Artery Disease (CAD)	1.2	1.4	3.3	-0.6	1.3	-0.3	-0.4	-1.5	-1.8	-1.7	0.0	0.4	-1.4	-0.9	-1.7	-1.0	-0.8	-1.6
Crohns Disease (2012)	0.6	1.0	2.2	-0.9	1.1	-0.3	-1.2	-0.8	-1.2	0.1	-0.8	-0.3	-1.4	-1.5	-1.1	-0.8	-0.4	-1.4
Mean Putamen Volume	1.3	1.5	3.6	1.6	-1.0	1.9	1.8	1.2	1.6	-0.6	1.4	-0.3	1.2	0.4	1.6	0.5	0.0	1.2
Fasting Glucose	0.7	0.9	2.7	0.9	-0.1	0.4	0.2	-0.5	-0.8	1.5	0.6	1.0	-1.0	-0.4	-1.0	-1.0	-1.6	-1.1
HbA1C	0.4	0.5	1.9	-0.7	-0.8	-0.5	-0.4	0.5	-0.8	-1.4	-0.2	-0.3	-0.6	0.1	-1.0	-0.7	-0.5	-0.8
HDL Cholesterol	0.5	0.9	2.3	0.7	0.7	0.4	0.5	-0.4	1.5	1.2	0.1	-1.5	0.7	0.5	1.3	1.0	1.2	0.8
LDL Cholesterol	0.2	0.3	0.9	0.5	0.3	-0.2	-0.1	-0.3	0.3	0.9	0.5	0.2	0.7	0.3	0.9	0.7	0.8	0.9
Lupus	0.8	1.2	4.9	-0.5	2.2	-0.8	-0.9	-1.8	0.3	-0.0	-1.3	2.2	-0.7	-0.7	0.2	0.1	0.8	-0.4
Neuroticism (2016)	0.9	1.2	3.9	-2.0	1.0	-1.4	-1.7	-0.2	-0.3	-1.5	-1.5	0.5	-0.2	-1.8	-0.2	-0.5	-0.6	-0.3
Primary Biliary Cirrhosis	1.0	1.5	4.5	2.1	-0.4	0.4	1.6	0.7	0.9	1.8	2.1	-0.0	0.3	2.0	0.8	0.4	0.5	0.6
Rheumatoid Arthritis	0.2	0.3	1.1	-0.0	0.0	-0.1	0.4	-0.9	-0.6	1.0	0.2	-0.0	-0.8	1.1	-0.3	0.0	0.7	-0.7
Schizophrenia (2014)	0.6	1.3	4.2	-0.6	0.1	1.1	-0.0	0.4	-2.0	-0.4	-0.5	-0.6	-1.9	0.3	-2.0	-0.9	-0.5	-2.0
Triglycerides	0.2	0.4	2.8	-0.1	0.2	0.1	0.2	-0.8	0.2	-0.0	0.3	1.7	0.7	0.4	0.2	0.1	0.8	0.8
Type 2 Diabetes (T2D) (2012)	1.6	1.9	5.7	2.0	-1.5	1.8	2.1	0.5	0.3	1.4	1.6	-2.4	0.1	1.9	0.4	-0.2	-0.5	0.5
Ulcerative Colitis	1.2	1.7	6.2	1.4	-0.7	2.5	1.7	1.0	0.6	1.6	1.4	-2.0	0.4	1.5	0.5	0.6	0.7	0.6
Blood Eosinophil Count	0.5	4.0	17.9	-0.8	-0.7	4.2	-1.5	0.3	-1.7	1.0	-1.7	4.0	-0.5	-2.4	-1.7	-1.2	-2.1	-1.0
Blood Platelet Count	0.5	5.3	13.6	3.6	-2.0	2.0	3.7	-0.8	1.6	1.9	3.4	-1.2	2.4	3.2	1.7	1.3	0.3	2.3
Blood Red Count	0.2	2.2	5.0	-1.1	1.4	-1.8	-1.0	-2.0	1.4	-0.5	-1.1	2.2	1.2	-2.0	1.5	1.0	1.3	1.5
Blood White Count	0.7	5.0	15.6	0.6	0.7	-4.0	-0.2	-2.7	-2.0	-1.9	1.0	-1.5	-3.6	-1.4	-2.0	-1.0	-3.0	-3.2
Heel T-Score	0.3	2.7	16.9	-0.8	0.8	-0.6	-0.9	-4.1	-0.8	-0.5	-1.4	-2.5	-1.4	-2.4	-0.8	-1.3	-0.9	-1.3
BMI	0.7	4.3	11.4	2.3	-3.4	1.8	3.0	1.9	1.6	-0.9	2.3	-2.8	1.2	3.2	1.5	-0.2	0.3	1.4
Height	0.0	0.5	1.2	-0.7	-0.7	0.0	0.1	0.9	0.7	1.0	-0.8	-0.5	0.8	-0.1	0.8	1.1	-0.4	0.8
Waist Hip Ratio (WHR)	1.9	8.7	30.5	-2.9	5.5	-3.2	-3.5	-3.3	-2.1	-0.8	-3.4	4.2	-2.0	-3.5	-2.0	0.0	0.1	-1.9
Systolic Blood Pressure	1.9	9.6	33.2	-0.7	2.8	-3.2	-2.7	-1.6	0.8	5.4	-2.3	5.8	-1.7	0.6	1.5	5.0	4.2	0.1
Smoking Status	0.2	0.5	1.4	0.9	-0.7	-0.1	0.7	-0.2	0.6	0.3	0.4	0.4	0.9	-0.1	0.4	-1.1	-1.2	0.6
Allergy or Eczema	0.2	0.5	1.7	-0.2	0.3	0.0	0.4	-0.6	1.3	-0.3	-0.4	0.5	1.0	0.1	1.1	1.2	0.5	0.9
Cardiovascular Disease	1.6	5.2	15.9	-1.9	2.9	-3.3	-2.7	-2.4	-0.2	0.6	-3.0	4.0	-1.9	-1.2	0.2	2.8	1.9	-0.9
Hypothyroidism (self reported)	0.5	1.2	4.0	-2.0	1.4	-1.3	-1.6	0.2	-0.0	1.2	-1.7	1.2	0.1	-0.3	0.1	0.4	1.5	0.3
Respiratory disease	0.3	0.8	4.0	-0.5	-0.6	-2.0	-0.8	-0.2	-0.1	-0.9	-0.2	1.2	0.2	0.0	0.0	2.0	-0.1	0.1
Type 2 Diabetes (T2D) (2018)	0.3	0.6	5.6	0.6	0.9	-0.4	0.3	-2.4	-0.3	0.8	0.5	0.3	-0.4	-0.1	-0.2	-0.2	0.6	-0.2
Lung FEV1/FVC ratio	1.2	6.1	20.9	4.2	-2.9	0.8	4.4	-0.2	0.9	-0.4	4.6	-2.8	1.4	2.9	0.9	-1.1	-0.7	1.2
Lung FVC	5.3	27.1	73.2	7.5	-5.1	4.5	7.9	1.3	2.5	4.7	8.6	-7.0	3.8	6.4	2.7	2.7	1.5	4.0
Neuroticism	0.3	0.8	1.6	-1.0	0.1	-0.8	-0.9	-0.5	1.1	-1.1	-1.0	0.1	1.3	-0.8	1.0	0.7	0.8	1.0
Chronotype (morning person)	0.6	1.4	3.3	-1.3	1.6	0.1	-1.1	-0.3	-1.4	-0.8	-1.6	0.2	-1.4	-1.8	-1.3	-0.9	-0.4	-1.5
Hair Pigment	0.1	1.4	4.4	-0.5	0.3	-0.6	0.1	-0.1	-1.4	-0.1	-0.0	0.5	-2.0	-0.5	-1.5	-2.1	-1.8	-2.0
Tanning	0.0	0.6	2.9	-0.8	0.1	-0.3	-0.5	-1.7	0.2	0.5	-0.6	-1.5	0.3	-0.1	0.1	-0.7	1.0	0.3
Hand grip strength (left)	1.0	2.7	11.1	1.1	-1.4	1.1	1.0	2.1	0.6	3.3	1.2	-0.9	1.8	1.2	0.8	2.1	1.7	1.8
Number of treatments/medications taken	0.4	0.7	1.5	1.1	-0.2	-0.3	1.0	0.2	-1.2	-0.2	1.0	-0.4	-1.2	0.7	-1.1	0.9	-0.6	-1.1
Average weekly spirits intake	1.7	2.2	4.3	2.0	-1.3	0.7	1.9	1.3	2.1	0.2	1.7	-1.0	1.1	1.9	2.0	0.5	1.1	1.5
Sensitivity / hurt feelings	0.5	0.9	4.6	-0.2	-1.5	1.3	0.9	0.8	0.3	-0.8	0.0	-2.1	0.8	-0.0	0.3	-1.3	-0.7	0.3
Frequency of depressed mood in last 2 weeks	3.8	5.4	21.9	-3.5	2.3	-2.4	-3.5	-2.0	-0.7	-0.7	-2.7	1.7	-1.2	-4.7	-0.7	-1.5	-1.3	-1.4
Hearing difficulty/problems: Yes	6.2	9.5	29.4	-5.1	4.2	-2.4	-4.2	-1.1	-1.2	0.2	-5.4	4.6	-1.3	-3.8	-1.2	-0.5	0.7	-1.5
Relative age of first facial hair	0.2	0.4	2.0	-0.1	0.6	0.8	0.2	1.4	-0.0	0.6	-0.6	0.7	0.6	0.3	0.2	0.6	0.8	0.6
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	2.9	-1.3	0.1	-1.0	-1.7	0.1	-0.5	-0.2	-1.4	1.6	-0.6	-1.6	-0.4	-0.6	-0.3	-0.7
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.4	-0.3	-0.7	-0.2	-0.2	-0.5	-0.2	-0.6	-0.2	0.5	0.2	0.2	-0.2	-0.1	0.1	0.0
Ever had hysterectomy (womb removed)	0.4	0.4	1.0	-0.6	0.3	-0.6	-0.2	-0.8	0.7	1.0	-0.3	0.0	1.0	-0.2	0.9	0.2	0.6	0.9
Systolic blood pressure, automated reading	1.1	3.2	12.8	-0.7	0.8	-1.6	-1.5	0.4	1.0	3.6	-1.6	3.1	-1.1	0.9	1.4	2.7	2.2	0.2
Eye problems/disorders: Diabetes related eye disease	1.4	1.6	5.0	0.5	-0.8	-0.9	-0.1	1.2	-1.4	-0.6	0.6	0.3	-1.8	0.5	-1.4	-2.2	-1.9	-1.8
Angina	0.8	1.0	2.9	0.9	0.8	0.1	0.2	-1.7	-1.3	-0.3	0.7	1.2	-1.4	-0.3	-1.2	0.5	-1.2	-1.2
Medication for hormone replacement therapy	1.7	1.9	5.1	0.9	-1.0	2.2	1.4	0.4	1.1	0.6	0.9	-1.8	1.2	2.2	1.3	1.6	1.1	1.4
Vitamin and mineral supplements	0.5	0.7	2.2	-0.5	0.7	-1.5	-1.0	-1.1	0.1	0.0	-1.3	1.1	-1.1	-0.7	0.3	0.9	-0.1	-0.7
Supplements: Zinc	0.5	0.5	1.7	-0.3	0.7	-1.2	-0.5	-1.3	-0.4	1.3	0.0	0.9	-0.4	-0.2	-0.3	-0.6	0.6	-0.3
Medication: Co-codamol	0.3	0.3	1.8	-0.0	0.0	0.1	0.1	-1.1	0.6	0.5	-0.3	-0.4	-0.0	0.2	0.8	1.3	0.7	0.2
Medication: Metformin	0.4	0.6	2.7	1.6	-0.0	0.6	0.7	-0.4	-0.4	-0.0	1.2	-0.1	-1.2	0.5	-0.4	0.3	-0.8	-1.0
Diabetes (father)	1.0	1.2	4.2	0.3	-0.3	0.1	-0.1	0.5	1.4	0.6	0.0	-1.2	1.1	0.7	1.6	2.0	1.7	1.5
Diabetes (mother)	0.5	0.7	2.8	0.4	0.1	-1.4	-0.2	-1.4	1.0	0.3	-0.2	-0.5	-0.5	-0.9	0.8	-0.5	-1.7	-0.2
Severe depression (siblings)	3.4	3.8	14.3	-2.8	1.1	-1.6	-3.8	-0.5	-1.7	-0.4	-2.9	1.9	-1.0	-2.9	-1.6	-1.0	-0.5	-1.4
Pack years adult smoking proportion	0.7	1.1	2.8	-0.2	0.2	-0.5	-0.5	0.1	-1.5	-1.2	-0.6	0.7	-1.6	-0.3	-1.6	-0.9	-1.6	-1.7
Impedance of leg (right)	0.4	1.8	9.1	0.1	1.5	-1.9	-1.2	-2.1	-0.0	0.1	-1.4	3.0	-0.4	-1.6	0.2	0.8	-0.2	0.0
Leg fat-free mass (left)	0.5	2.4	6.0	1.0	-1.8	2.1	2.0	2.3	1.2	0.3	1.6	-2.5	1.4	1.6	1.2	0.5	0.5	1.1
Trunk fat percentage	0.9	3.7	9.4	2.6	-2.7	2.8	3.1	1.3	1.2	-1.3	2.4	-1.9	0.4	2.9	1.0	-0.6	-0.9	0.5
Hand grip strength (right)	1.0	2.6	15.0	0.8	-0.7	0.5	0.7	1.6	0.5	3.9	0.7	0.1	1.7	0.7	1.0	2.8	1.9	1.9
Townsend deprivation index at recruitment	0.7	1.0	2.2	-1.1	0.5	-0.9	-1.5	-1.1	0.5	0.2	-1.2	0.9	1.3	-1.2	0.7	0.7	1.4	1.0
Current tobacco smoking	0.3	0.5	2.1	0.9	-1.0	-0.5	0.6	-0.8	-0.4	0.5	0.7	0.3	-0.3	0.6	-0.4	-1.1	-1.5	-0.5
Average weekly fortified wine intake	0.7	0.8	2.6	1.3	-1.5	-0.6	0.1	-0.2	-0.6	0.6	0.9	-1.6	-0.3	0.7	-0.7	-1.0	-1.4	-0.4
Maternal smoking around birth	1.0	1.4	3.2	-1.7	0.8	-0.7	-1.5	-1.5	-0.8	-1.4	-0.9	0.6	-0.6	-1.7	-0.8	-1.8	-0.8	-0.9
Fed-up feelings	1.8	3.2	8.7	-2.6	1.8	-2.3	-2.6	-1.6	-0.8	-1.0	-2.1	1.8	-1.1	-3.0	-0.9	-0.9	-0.9	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	3.0	4.0	10.5	-1.4	1.4	-2.6	-1.8	-1.1	-1.8	-2.1	-0.4	0.1	-1.9	-3.2	-1.9	-2.6	-2.7	-2.2
Relative age voice broke	0.3	0.5	3.6	-0.2	-0.3	0.7	-0.6	1.9	-1.1	-0.0	-0.7	-0.1	0.1	-0.2	-0.9	0.4	-0.7	-0.1
Taking other prescription medications	0.2	0.3	0.9	1.0	-0.9	-0.9	0.4	0.2	-0.5	0.2	0.8	0.2	0.1	0.7	-0.5	0.5	-0.1	-0.0
Age when periods started (menarche)	0.2	0.6	2.3	0.6	-0.8	-0.6	0.2	0.9	-0.3	1.5	0.8	-0.5	-0.8	0.1	-0.1	1.4	-0.8	-0.5
Bilateral oophorectomy (both ovaries removed)	1.9	2.2	9.8	-1.1	1.2	-1.0	-0.7	-3.1	1.1	0.6	-1.3	0.9	1.7	-0.9	1.3	1.1	2.2	1.9
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	3.0	0.4	-0.2	1.7	-0.2	-0.4	0.7	0.6	0.1	-1.1	0.6	-0.1	0.7	0.3	1.1	0.5
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	2.4	-1.2	1.0	0.4	-1.0	-0.7	0.1	0.9	-1.6	0.7	0.1	-0.5	0.0	-0.4	0.2	0.1
Qualifications: CSEs or equivalent	0.9	1.2	4.2	0.2	1.8	0.5	0.2	-2.0	1.0	-0.4	-0.1	0.1	1.4	-1.2	1.0	1.3	1.6	1.3
Serious illness, injury or assault to yourself	0.9	1.1	3.5	-1.8	0.7	-1.3	-1.8	-1.1	-0.1	-0.2	-1.9	1.0	-0.6	-1.4	-0.1	-0.1	-0.4	-0.7
High blood pressure	1.8	5.1	16.6	-2.1	2.3	-3.2	-3.1	-1.3	-0.5	0.7	-3.1	4.1	-2.4	-0.8	-0.1	2.6	1.7	-1.4
Hayfever, allergic rhinitis or eczema	0.8	1.8	4.7	0.2	0.9	0.7	1.1	-1.1	2.2	0.8	0.1	0.1	1.9	0.3	2.0	2.1	1.6	1.9
Multivitamins +/- minerals	0.7	0.9	2.7	1.0	-0.9	1.1	1.2	0.8	0.7	-0.8	1.6	-0.7	1.3	0.4	0.4	-0.3	0.3	1.1
Stomach or abdominal pain in last month	1.1	1.4	4.1	-1.1	1.8	-1.3	-1.1	-2.0	0.2	-0.2	-1.5	1.8	0.4	-1.7	0.1	0.2	0.4	0.3
Supplements: Glucosamine	0.4	0.5	2.8	0.8	-0.2	-0.4	0.7	0.2	0.6	-0.2	1.3	-1.7	0.3	0.7	0.5	-0.3	-0.3	0.2
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.5	-0.6	1.0	1.2	0.1	-0.8	1.1	-0.4	-0.7	-0.2	-0.0	-0.1	1.1	0.1	0.3	0.2
Medication: Atenolol	1.1	1.3	4.7	-0.7	1.0	-0.7	-1.1	-2.1	-0.7	-2.2	-0.9	1.1	-1.5	-0.4	-0.8	0.3	0.1	-1.2
Medication: Levothyroxine sodium	1.2	2.0	5.7	-2.4	1.2	-0.8	-1.9	1.7	-1.4	0.4	-1.9	1.5	-0.8	-1.6	-1.4	-0.8	-0.4	-1.1
Sitting height	0.2	1.3	6.7	1.4	-0.9	0.3	1.7	0.0	0.6	1.2	0.9	-0.8	0.8	1.4	0.7	2.6	0.7	0.9
Chronic bronchitis/emphysema (father)	0.6	0.7	2.4	-1.5	-0.1	0.2	-0.7	-0.1	-0.7	-0.9	-1.2	0.6	-1.2	-0.5	-0.6	0.1	-1.0	-1.1
High blood pressure (mother)	0.7	1.0	5.0	0.4	0.3	-2.0	-0.4	-2.2	-0.4	0.1	0.8	0.3	-1.3	-0.1	-0.4	1.2	-0.6	-0.9
Body mass index (BMI)	0.6	2.5	5.7	1.6	-2.2	2.1	2.4	1.4	1.3	-0.4	2.0	-2.1	0.9	2.2	1.2	-0.4	0.3	0.9
Impedance of leg (left)	0.3	1.5	6.9	0.2	1.3	-1.8	-1.1	-2.1	0.5	0.1	-1.4	2.6	-0.0	-1.2	0.6	1.4	0.0	0.4
Leg predicted mass (left)	0.4	2.3	5.7	0.9	-1.7	2.1	2.0	2.3	1.2	0.3	1.6	-2.4	1.4	1.6	1.2	0.5	0.5	1.2
Trunk fat mass	0.8	3.5	8.8	2.3	-2.5	2.6	3.0	1.7	1.5	-0.8	2.2	-2.0	0.7	2.7	1.4	-0.2	-0.6	0.9
Waist circumference	0.4	1.4	3.1	1.2	-1.6	1.2	1.8	1.3	0.9	-0.9	1.3	-1.5	0.6	1.7	0.8	-0.3	-0.5	0.5
Number of incorrect matches in round	1.4	2.3	4.6	1.9	-2.2	1.3	2.1	0.1	1.9	0.6	1.6	-0.6	2.0	1.5	1.8	0.2	-0.1	2.0
Past tobacco smoking	0.7	1.2	5.6	-1.5	1.2	-0.2	-0.6	-0.2	0.1	1.0	-1.3	0.7	0.0	0.3	0.2	2.4	2.2	0.3
Alcohol usually taken with meals	0.7	1.2	3.9	1.2	-1.5	1.6	1.7	0.5	0.4	0.1	1.5	-2.0	0.5	1.0	0.2	0.9	-0.3	0.4
Nervous feelings	1.5	2.8	8.6	-1.1	0.3	-0.6	-0.5	0.3	2.3	1.0	-1.4	1.1	2.6	-0.6	2.5	1.1	2.9	2.6
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	4.0	-2.0	1.3	-0.0	-1.1	-0.7	0.6	-0.9	-1.7	-0.3	0.2	-2.0	0.5	0.5	0.1	0.1
Hearing difficulty/problems with background noise	2.7	4.3	13.7	-3.6	1.1	-1.8	-2.4	-1.1	-1.6	-1.4	-3.7	2.2	-1.7	-2.3	-1.7	-1.1	-0.7	-1.9
Hair/balding pattern: Pattern 2	0.2	0.3	1.9	0.5	-0.7	-1.4	-0.4	0.5	-0.1	0.1	0.3	-0.0	-0.0	0.3	-0.1	-0.8	-0.6	0.1
Had menopause	0.3	0.4	1.8	-1.1	-0.2	-0.3	-0.8	-0.5	0.1	-1.3	-1.0	0.2	0.0	0.0	-0.1	-0.8	-0.6	-0.1
Had other major operations	1.0	1.2	3.4	-1.2	0.3	-0.2	-1.1	0.7	-1.4	-0.9	-0.8	-0.7	-0.6	-1.7	-1.4	-1.8	-1.4	-1.0
Forced vital capacity (FVC)	2.8	10.9	29.3	5.0	-2.8	2.6	5.0	0.7	1.9	3.1	5.4	-3.5	3.1	3.3	2.1	2.7	1.3	3.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	1.5	-0.1	0.2	1.2	-0.1	-0.6	-0.0	0.5	-0.1	-0.6	0.3	-0.6	-0.1	0.3	0.7	0.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.3	-0.5	0.7	-1.2	-0.4	-1.0	-0.4	0.7	-0.5	-0.2	-0.2	-0.9	-0.1	0.6	0.5	-0.1
Qualifications: None of the above	0.9	2.0	6.4	-1.7	1.1	-1.2	-2.0	-2.1	0.1	-1.7	-1.7	0.5	-0.5	-2.5	0.0	-1.3	-1.0	-0.8
Financial difficulties in last 2 years	1.9	2.5	6.7	-1.8	2.6	-2.1	-1.5	-2.1	-0.6	-1.4	-1.6	2.0	-0.9	-2.4	-0.5	-0.5	0.3	-0.9
Mouth/teeth dental problems	0.7	1.0	4.3	1.1	-1.0	1.1	2.1	-0.3	0.0	-0.6	1.8	-1.0	0.7	1.5	-0.3	-0.6	-0.1	0.4
Heart attack	0.8	1.0	2.9	1.2	-0.3	1.1	-0.1	-0.9	-0.9	-1.5	1.0	0.1	-1.3	-0.1	-1.0	-0.1	-1.7	-1.1
Allergy	0.8	1.8	5.2	-0.1	0.1	0.0	-1.1	0.5	-2.3	0.2	-0.4	-0.3	-2.1	-0.6	-2.0	-2.0	-1.6	-2.0
Pain all over the body in last month	0.6	0.7	4.4	-0.2	0.5	-0.6	-0.8	-1.6	-0.4	0.2	0.1	0.2	0.2	-1.0	-0.2	2.1	0.7	0.2
Diabetes (self-reported)	0.7	1.1	2.6	-0.0	0.6	-0.8	-0.9	-1.6	-1.6	-0.5	-0.2	0.2	-1.4	-0.4	-1.6	-1.3	-1.1	-1.4
Hayfever/allergic rhinitis (self-reported)	1.2	1.5	4.5	0.9	0.6	0.6	1.4	-0.1	1.2	1.6	0.9	0.3	1.3	0.8	1.3	2.1	2.0	1.4
Medication: Ramipril	0.7	0.9	4.6	-0.5	0.2	-1.4	-1.0	-0.2	0.6	0.7	-0.7	2.2	0.7	0.5	0.7	1.5	0.8	0.7
Medication: Simvastatin	0.5	0.8	2.9	0.3	0.8	0.6	-0.0	-1.0	-0.6	-0.3	0.7	0.3	-1.3	-0.9	-0.6	-1.7	-0.9	-1.3
Fluid intelligence score	0.2	0.4	1.5	-0.6	0.1	-0.0	-0.1	0.4	-0.8	-0.0	-0.4	-0.4	-1.2	0.6	-0.9	0.0	-0.4	-1.2
Illnesses of siblings	0.6	0.9	4.3	0.1	0.4	-1.1	-0.0	0.9	0.6	0.8	-0.2	0.3	1.1	1.1	0.6	1.4	2.1	1.2
Neuroticism score	0.4	0.8	2.2	-1.5	0.7	-0.6	-1.3	-0.5	0.4	-1.5	-1.3	0.7	0.6	-1.4	0.4	-0.4	0.3	0.2
Weight	0.7	3.7	7.5	1.9	-2.5	2.1	2.7	2.3	1.8	0.1	2.0	-2.1	1.6	2.6	1.8	0.9	0.5	1.6
Impedance of arm (right)	0.1	0.3	1.4	0.9	-0.0	1.2	0.0	0.2	-0.4	-0.3	-0.2	1.1	-0.7	0.2	-0.3	0.1	-0.7	-0.4
Arm fat percentage (right)	1.1	4.2	11.1	2.5	-2.7	3.3	3.0	2.1	1.0	-1.0	2.5	-2.4	0.4	3.0	0.9	-0.8	-0.4	0.5
Trunk fat-free mass	0.4	2.0	4.1	0.5	-1.1	0.6	1.5	2.0	1.5	1.6	1.0	-1.5	1.9	1.1	1.5	1.8	1.1	1.7
Hip circumference	2.1	9.2	24.8	3.1	-5.0	3.4	4.1	3.5	2.2	0.1	3.6	-3.9	2.1	4.1	2.0	0.4	-0.3	1.9
Time employed in main current job	0.7	0.8	3.4	1.3	-0.2	0.3	0.6	-0.7	0.6	1.1	0.6	-1.6	-0.5	0.7	0.6	1.8	-0.0	-0.1
Alcohol intake versus 10 years previously	0.9	1.3	5.2	-1.5	2.3	-0.4	-1.3	-0.6	0.3	-0.2	-1.9	1.0	0.3	-1.6	0.4	0.9	1.3	0.4
Father’s age at death	1.4	1.9	5.2	0.5	-2.1	0.7	0.4	1.9	2.3	0.1	0.4	-0.4	2.0	1.3	2.0	0.1	0.3	2.0
Worrier / anxious feelings	0.1	0.2	0.7	-0.0	-0.0	0.8	0.4	0.4	0.0	-0.7	0.1	-0.5	0.7	-0.5	0.1	0.3	0.5	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	4.2	-1.0	1.3	-1.5	-1.1	-1.3	0.6	-0.5	-1.0	1.3	0.1	-2.0	0.7	0.5	-0.5	0.1
Falls in the last year	0.9	1.3	5.4	-1.1	0.7	-2.1	-1.1	-2.3	0.0	-0.9	-1.1	0.1	-0.9	-1.3	0.0	-0.3	-0.8	-0.9
Hair/balding pattern: Pattern 3	1.0	1.5	5.1	1.6	0.3	1.4	1.4	-1.7	1.2	-0.5	1.7	-2.3	0.5	0.1	1.0	-1.4	-0.7	0.4
Number of live births	0.2	0.3	1.0	0.2	0.1	-0.7	0.8	-0.6	-0.5	0.9	1.0	0.3	0.6	-0.1	-0.6	-0.1	-0.2	0.2
Forced expiratory volume in 1-second (FEV1)	2.9	9.8	28.9	4.8	-2.3	1.9	4.9	0.0	1.8	2.8	5.4	-3.5	3.3	2.8	2.0	2.0	1.3	3.2
Pulse rate	0.6	0.9	5.9	-0.4	1.6	-0.7	-0.4	0.1	0.7	-0.9	-0.9	2.4	0.3	-1.2	0.6	0.8	0.1	0.3
Happiness	0.5	0.7	2.1	0.9	-0.5	-0.1	1.2	-0.7	1.4	0.1	1.2	-0.4	0.6	0.1	1.4	0.1	-0.1	0.8
Noisy workplace	0.9	1.2	3.0	-1.0	0.8	-1.3	-0.6	-0.5	0.9	1.6	-1.7	0.4	1.2	-0.8	1.0	1.0	1.1	1.4
Qualifications: A levels/AS levels or equivalent	0.7	1.6	4.0	1.6	0.1	1.9	2.0	2.0	-0.3	0.5	1.8	-1.1	0.1	1.6	-0.0	1.1	0.8	0.4
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	10.3	-0.8	1.1	0.1	-0.3	-0.6	-1.3	-2.4	-0.1	-1.7	-0.8	-1.7	-1.6	-3.2	-2.0	-1.3
Mouth/teeth dental problems: Dentures	0.3	0.5	2.2	0.3	-1.2	-0.6	-0.5	1.3	-0.4	-0.3	-0.1	0.6	-0.6	-0.3	-0.2	-0.3	-1.5	-0.6
Asthma	0.6	1.2	5.1	-0.2	-1.0	-1.5	0.1	-1.0	0.7	-0.6	0.3	1.3	1.1	0.8	0.7	2.3	1.2	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.6	-0.8	0.6	-0.7	0.3	-0.7	-0.9	-1.1	-0.3	-1.1	-0.2	-1.3	-0.9	-1.0	-0.9	-0.5
Medication: Cholesterol lowering	1.5	2.4	6.4	0.7	1.0	0.8	-0.0	-1.5	-2.1	-1.2	0.8	0.3	-2.5	-0.9	-2.1	-1.7	-2.1	-2.5
Depression (self-reported)	1.1	1.3	6.6	-0.1	1.2	-0.6	-0.6	-1.4	-1.3	-2.6	-0.4	0.5	-0.8	-1.3	-1.3	-0.9	-0.9	-1.1
Medication: Lansoprazole	0.3	0.4	2.1	0.4	-0.4	-0.3	0.0	0.4	1.0	-0.1	-0.2	-0.2	0.4	0.2	1.1	1.4	-0.2	0.5
Prospective memory result	0.7	0.9	3.2	0.8	-0.7	-0.5	0.9	-0.6	0.7	0.6	1.1	-0.7	0.5	1.8	0.8	1.6	0.9	0.7
Lung cancer (father)	1.7	2.0	5.3	0.2	-0.6	-0.9	-0.4	-0.1	-1.8	-1.7	0.1	-0.6	-2.0	-0.5	-1.8	-2.1	-2.3	-2.2
Illnesses of mother	0.5	0.6	2.4	-1.1	0.1	0.3	-0.5	1.2	-0.4	-1.1	-1.2	0.5	0.4	-0.9	-0.5	-1.5	-0.1	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	2.9	9.2	24.6	4.5	-2.3	2.8	5.0	0.5	1.4	2.6	4.8	-3.7	2.6	3.1	1.7	2.2	1.4	2.7
Pulse wave Arterial Stiffness index	2.1	2.4	8.6	0.4	-0.4	-1.6	-0.0	-0.6	-1.9	-1.1	0.2	0.5	-2.9	0.6	-2.0	-1.8	-2.1	-2.7
Impedance of arm (left)	0.1	0.5	1.4	0.9	-0.1	1.1	0.3	-0.1	-0.7	-1.2	0.1	0.7	-0.6	0.4	-0.7	-0.4	-0.9	-0.5
Arm fat mass (right)	1.0	4.2	9.5	2.5	-2.8	2.8	3.1	1.6	1.6	-0.7	2.5	-2.5	1.2	3.0	1.5	-0.1	0.1	1.2
Trunk predicted mass	0.4	2.0	4.0	0.5	-1.1	0.6	1.4	2.0	1.5	1.8	1.0	-1.5	1.9	1.1	1.5	1.8	1.1	1.7
Standing height	0.2	2.0	7.7	1.0	-0.9	0.4	1.4	1.6	1.6	0.7	0.4	-0.5	2.0	1.1	1.7	2.8	0.5	1.9
Length of working week for main job	0.3	0.3	1.9	0.5	-0.8	0.9	0.3	1.4	0.2	-0.4	0.1	-0.5	-0.0	-0.2	0.1	-1.0	-0.1	0.1
Exposure to tobacco smoke at home	0.3	0.3	1.4	0.4	-0.4	0.9	-0.2	0.2	-0.2	-1.2	0.1	0.3	-0.5	0.3	-0.2	-0.5	-0.9	-0.4
Breastfed as a baby	0.6	0.7	3.8	0.2	-0.2	1.4	-0.1	1.3	-0.1	-2.0	0.1	-0.0	-0.0	-0.9	-0.3	-0.6	-1.3	-0.3
Tense / ‘highly strung’	0.4	0.7	3.0	-1.2	-0.2	-0.2	-1.4	-0.3	0.1	-1.7	-1.4	0.5	0.4	-0.8	0.1	-1.1	0.2	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.9	2.9	11.7	-1.8	1.3	-1.6	-0.9	-2.0	1.3	0.8	-1.7	0.6	2.0	-0.7	1.4	1.7	3.4	2.1
Hair/balding pattern: Pattern 4	0.5	1.1	5.3	-1.3	0.8	0.5	-0.6	-0.5	-1.1	1.7	-0.5	1.6	-0.4	0.3	-0.8	0.6	2.3	-0.4
Birth weight of first child	0.4	0.8	2.3	-1.4	0.4	-0.6	-0.5	-0.7	0.7	0.5	-1.0	-0.7	1.5	-0.6	0.9	0.6	1.1	1.3
Peak expiratory flow (PEF)	2.4	5.6	13.3	3.0	-1.6	0.6	3.5	-0.3	2.1	1.8	3.6	-1.8	3.2	2.0	2.2	2.1	1.6	3.1
Pulse wave reflection index	2.6	3.2	6.4	-1.4	1.2	-2.2	-1.7	-2.4	-2.2	-0.2	-1.2	1.4	-2.5	-1.5	-2.1	-1.8	-1.0	-2.4
Ever highly irritable/argumentative for 2 days	2.4	2.9	8.9	-1.6	0.6	-3.0	-1.9	-2.5	-2.0	-0.8	-1.8	1.0	-1.7	-1.6	-1.8	-1.2	-0.7	-1.8
Loud music exposure frequency	0.6	0.7	1.6	-0.0	-1.1	-0.9	-0.8	0.7	-1.0	0.5	-0.5	1.0	-1.3	-0.4	-0.9	-0.3	-1.0	-1.0
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	2.7	-0.1	1.6	0.3	0.6	0.1	-0.4	0.8	0.2	0.5	-0.5	0.3	-0.2	0.9	1.1	-0.1
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	6.2	-0.9	1.7	-0.1	-0.9	-0.6	1.6	1.0	-1.5	-0.2	0.6	-0.5	1.7	2.0	2.5	1.1
Blood clot in the leg (DVT)	0.2	0.3	0.8	0.5	-0.1	0.1	0.8	-0.6	0.9	-0.9	0.4	0.3	0.4	0.3	0.6	-0.5	-0.2	0.4
Medication: Paracetamol	0.5	0.9	4.3	-0.7	0.0	-0.4	0.3	-1.2	0.8	-1.2	-0.2	-2.1	1.3	-1.0	0.7	-0.7	-0.5	0.7
Headache pain in last month	0.1	0.3	1.1	-0.1	0.2	0.7	1.0	-0.0	0.5	0.4	-0.3	-0.1	0.8	0.4	0.4	0.1	0.4	0.6
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	6.9	-0.5	-0.4	0.6	0.3	1.2	1.5	1.2	-0.3	-0.5	2.6	-0.0	1.4	0.1	1.5	2.3
Glaucoma (self-reported)	0.8	0.9	3.2	0.5	-0.7	-0.3	1.1	0.1	-1.7	-0.3	1.5	-0.1	-0.4	-0.6	-1.8	-1.1	-1.0	-0.9
Gout (self-reported)	1.8	2.4	5.3	2.3	-2.3	0.7	1.9	2.0	1.6	0.4	2.2	-0.5	1.5	1.6	1.5	0.1	-0.7	1.5
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	3.7	-1.9	1.1	-1.1	-1.7	0.5	-1.7	0.4	-1.6	1.3	-1.2	-0.6	-1.6	-1.0	-0.2	-1.3
Medication: Amlodipine	0.3	0.4	1.4	0.0	0.4	0.3	-0.5	0.6	-0.8	-1.2	-0.3	0.5	-1.2	-0.2	-0.7	0.3	-0.5	-1.0
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.9	1.0	-1.1	0.3	1.3	-0.0	-0.1	-1.4	1.3	-1.3	-0.7	1.7	-0.1	0.4	-0.4	-0.5
Birth weight	0.6	1.3	6.4	-2.3	1.2	-0.3	-1.8	0.5	0.3	-0.3	-2.5	0.0	-0.3	-1.4	0.4	0.5	0.6	-0.1
Chronic bronchitis/emphysema (mother)	0.9	1.1	3.3	-1.8	0.8	-0.9	-1.6	-0.3	-1.1	0.4	-1.5	0.7	-1.0	-0.6	-1.1	-1.0	-0.0	-1.0
High blood pressure (siblings)	0.4	0.6	2.4	0.6	-0.9	0.4	0.3	-0.8	0.2	-0.6	0.9	-0.6	-0.9	0.4	0.1	-1.1	-1.6	-0.7
Forced vital capacity (FVC), Best measure	2.5	9.1	21.5	4.2	-2.3	3.2	4.6	1.0	1.2	3.2	4.4	-3.7	2.3	3.2	1.6	3.0	1.7	2.5
Body fat percentage	0.9	3.6	8.3	2.5	-2.6	2.7	2.9	1.6	1.3	-1.3	2.2	-1.9	0.4	2.7	1.2	-0.7	-0.8	0.6
Leg fat percentage (right)	0.4	1.6	3.7	1.8	-1.9	1.5	1.8	1.1	1.1	-0.8	1.4	-1.4	-0.1	1.5	1.0	-0.6	-1.0	0.2
Arm fat-free mass (right)	0.4	2.1	4.1	1.0	-1.5	0.9	1.7	1.8	1.7	1.0	1.4	-1.6	2.0	1.2	1.7	1.1	0.8	1.9
Exposure to tobacco smoke outside home	0.4	0.5	1.7	-1.1	0.2	-1.2	-0.7	-0.1	-0.3	-1.3	-1.0	1.1	0.0	-0.3	-0.3	-0.5	-0.4	-0.2
Comparative body size at age 10	0.4	1.0	3.0	1.2	-1.7	0.7	0.4	1.7	-0.0	1.5	1.1	-1.1	-0.6	1.2	-0.2	-0.5	-0.9	-0.5
Number of full brothers	0.3	0.4	2.1	-0.5	0.5	0.5	-0.2	-1.5	-0.3	-0.7	-0.1	-1.0	0.2	-0.2	-0.5	-1.0	-0.2	-0.0
Worry too long after embarrassment	0.2	0.4	1.3	-0.3	0.3	0.8	0.1	-0.5	0.7	-0.5	-0.2	0.2	1.1	-0.8	0.6	-0.4	0.3	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	3.0	-1.4	0.1	-1.3	-1.2	-0.4	-1.1	-1.7	-1.2	0.3	-1.6	-0.7	-1.1	-0.9	-0.9	-1.5
Wheeze or whistling in the chest in last year	0.9	1.6	8.3	-1.8	0.3	-1.0	-1.5	-1.2	-1.1	-2.9	-1.0	0.3	-0.5	-1.4	-1.2	-0.6	-1.1	-0.9
Number of children fathered	1.1	1.3	2.9	1.1	-0.8	1.1	1.7	1.2	-1.6	-0.1	1.4	-1.7	-0.1	1.0	-1.4	-0.9	-0.4	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.9	0.9	-1.2	-1.3	0.0	-0.4	-0.1	-1.2	0.5	-0.7	-0.7	0.5	-0.3	-0.5	-1.4	-0.6
Age at first live birth	1.0	1.7	9.9	0.7	-0.7	2.0	1.0	3.1	0.7	0.8	0.5	-0.3	1.3	1.1	0.7	1.6	0.9	1.3
Pulse wave peak to peak time	2.0	2.3	7.9	-0.1	0.4	1.6	0.1	0.6	1.9	1.0	-0.1	-0.5	2.8	-0.4	2.0	2.0	1.9	2.7
Health satisfaction	0.4	0.5	2.9	-0.0	0.9	-0.8	-0.1	-1.0	0.1	1.7	-0.4	0.0	-0.6	-0.8	0.3	0.6	0.9	-0.2
Shortness of breath walking on level ground	0.4	0.5	2.3	-0.3	0.4	-0.2	-0.1	-0.4	-0.8	-0.0	0.3	-0.0	-0.8	-1.2	-0.9	-1.5	-0.8	-0.9
Qualifications: College or University degree	0.9	2.9	9.1	1.6	-1.8	2.9	3.0	2.4	-0.7	0.6	2.0	-1.4	1.0	2.2	-0.5	1.0	-0.0	0.8
Eye problems/disorders: None of the above	0.4	0.5	3.2	0.3	0.9	1.8	0.2	-0.1	-0.2	-0.9	0.2	-1.1	-0.3	0.1	-0.0	-0.3	0.6	-0.3
Mouth/teeth dental problems: Loose teeth	1.0	1.1	3.2	-0.4	-0.8	-1.3	-0.8	0.7	-1.0	-1.1	-0.4	-0.7	-1.1	-0.8	-1.1	-1.8	-1.7	-1.3
Emphysema/chronic bronchitis	2.7	3.1	6.7	-2.0	0.4	-1.8	-2.6	0.4	-1.8	-1.6	-1.5	2.3	-2.2	-1.9	-1.7	-1.1	-0.8	-2.2
Medication for pain relief, constipation, heartburn	0.3	0.6	1.5	0.8	-1.2	0.8	0.7	0.9	-0.8	0.1	1.2	0.0	-0.6	1.1	-0.7	0.2	-0.1	-0.4
Neck or shoulder pain in last month	2.1	3.0	6.6	-2.1	1.5	-1.6	-2.0	-1.5	-1.7	-0.6	-2.6	0.5	-2.5	-1.7	-1.6	-0.9	-1.1	-2.2
Medication: Blood pressure	0.4	0.8	4.0	0.0	-0.1	-0.2	-0.5	0.6	-0.4	-1.0	-0.6	0.8	-1.7	0.8	-0.2	2.0	0.3	-1.2
Angina (self-reported)	0.9	1.1	4.6	0.5	1.1	-0.3	0.0	-2.1	-1.3	-0.3	0.5	1.5	-1.4	-0.5	-1.2	0.4	-1.1	-1.2
Migraine (self-reported)	1.2	1.5	6.6	-0.9	1.0	1.0	0.1	0.0	0.9	0.3	-1.4	-1.4	0.8	0.9	1.0	2.0	2.6	0.9
Medication: Ibuprofen	0.8	0.9	2.4	-0.4	0.8	-0.6	0.5	-0.5	-1.3	-0.9	0.1	-1.6	-0.4	-1.1	-1.4	-1.4	-1.1	-0.8
Medication: Allopurinol	1.5	1.9	3.8	1.9	-1.9	0.4	1.5	1.4	1.9	-0.4	1.3	-0.9	1.9	1.1	1.7	-0.1	-0.5	1.7
Medication: Omeprazole	1.7	2.1	7.4	-1.5	2.1	-1.5	-2.3	-0.3	0.5	-0.1	-2.6	2.7	-0.5	-1.4	0.6	0.1	0.4	-0.3
Medication: Seretide 50 evohaler	1.0	1.1	6.4	0.9	-2.5	-0.1	0.5	1.6	-0.2	0.8	1.2	-0.3	0.7	1.8	-0.3	-0.3	-0.7	0.4
Mean time to correctly identify matches	0.5	1.0	3.9	0.5	-2.0	-0.3	0.7	-1.0	0.5	-1.2	0.9	-1.6	-0.6	1.2	0.4	-0.3	-1.5	-0.6
Heart disease (mother)	0.8	1.0	3.0	-0.8	1.1	-0.5	-1.6	-0.7	1.2	-0.1	-1.3	1.7	0.1	-1.4	1.3	0.3	0.3	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	4.1	-0.1	1.1	-0.9	0.2	-2.0	0.6	-0.4	0.0	1.2	0.3	-0.2	0.5	0.1	0.8	0.4
Whole body fat mass	0.9	3.8	8.7	2.4	-2.5	2.7	3.0	1.7	1.9	-0.8	2.2	-2.2	1.0	2.8	1.8	0.2	-0.2	1.2
Leg fat mass (right)	0.7	2.8	6.2	2.1	-2.2	2.3	2.5	1.5	1.7	-0.4	2.0	-2.1	0.7	2.0	1.6	-0.0	-0.4	0.9
Arm predicted mass (right)	0.4	1.8	3.6	0.8	-1.2	0.7	1.7	1.6	1.5	1.0	1.4	-1.5	1.9	1.0	1.5	1.2	0.7	1.7
Pulse rate, automated reading	0.3	1.1	4.3	-1.3	1.6	-0.9	-0.3	0.2	0.4	1.4	-1.5	2.1	0.0	-0.2	0.5	0.6	1.2	0.2
Alcohol intake frequency.	1.0	2.4	9.0	-2.1	1.3	-3.0	-1.8	-0.8	-0.5	0.2	-2.3	2.4	-0.9	-1.4	-0.2	1.3	0.4	-0.7
Comparative height size at age 10	0.2	1.1	3.5	1.3	-0.7	0.2	1.8	-0.3	0.6	0.8	1.0	-1.9	1.0	1.1	0.7	1.5	0.3	0.9
Number of full sisters	0.5	0.6	1.4	0.5	-1.2	0.6	0.8	0.8	0.9	-0.4	0.7	-0.1	1.0	0.1	0.9	1.1	-0.5	0.9
Suffer from ‘nerves’	1.3	2.1	4.8	-0.3	1.1	-0.6	-1.0	-0.5	2.1	0.4	-0.9	0.7	2.2	-1.8	2.2	1.1	1.9	2.2
Overall health rating	1.1	2.4	6.6	-1.7	2.3	-1.1	-1.9	-2.2	-0.2	-1.3	-2.1	2.1	-0.8	-2.6	-0.1	0.3	0.6	-0.7
Chest pain or discomfort	1.4	2.0	10.2	-0.5	1.2	-1.3	-0.7	-3.2	-1.1	-1.9	0.0	1.2	-1.4	-1.5	-1.3	-0.6	-0.9	-1.4
Had major operations	1.2	1.4	3.0	0.7	0.5	0.6	0.7	-0.3	-1.6	-1.7	1.3	-0.8	-1.2	-0.1	-1.6	-1.4	-1.7	-1.4
Age at last live birth	0.8	1.1	10.7	0.2	-0.9	0.9	0.3	3.3	-0.6	0.5	0.1	-0.2	-0.6	0.0	-0.5	1.2	-1.0	-0.6
Family relationship satisfaction	0.8	1.0	2.6	1.1	-1.2	-0.3	1.5	-0.2	1.5	-0.1	1.2	-0.8	0.6	1.6	1.2	-0.0	-0.0	0.8
Leg pain on walking	0.8	1.0	2.9	-0.3	1.2	-1.1	-0.7	-1.1	0.6	1.4	-0.9	0.6	0.4	-0.4	0.8	1.7	1.5	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.3	-0.5	0.7	-1.1	-0.7	0.8	-0.3	0.2	-0.5	0.1	-0.4	-0.4	-0.4	-0.2	-0.1	-0.5
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.7	-0.2	-0.6	-0.2	-0.0	-0.0	-1.3	-1.0	0.3	-1.6	-1.0	-0.2	-1.3	-0.9	-1.1	-1.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.6	-0.1	-0.4	-0.4	0.1	0.5	-0.7	-0.3	-0.2	0.1	-0.8	0.4	-0.8	-0.1	-0.1	-0.7
Medication: Aspirin	0.5	0.6	2.2	-0.1	0.8	-0.5	-1.2	-0.3	-1.2	-0.0	-0.3	1.5	-1.1	-0.2	-1.1	-0.2	0.1	-0.9
Supplements: Vitamin C	0.2	0.3	1.0	0.2	0.7	1.0	0.6	0.3	-0.2	0.8	0.5	-0.2	0.5	0.5	-0.1	0.5	0.8	0.3
Knee pain experienced in last month	1.3	2.0	4.4	-1.3	1.3	-1.6	-2.1	0.5	0.0	-1.1	-1.9	1.4	-1.4	-2.1	-0.0	-1.3	-1.6	-1.2
Hypertension (Self-reported)	1.6	4.4	14.6	-1.9	2.1	-2.7	-2.7	-1.2	-0.0	0.9	-2.9	3.8	-2.0	-0.5	0.3	2.9	2.1	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.7	0.7	-0.6	0.4	0.1	-0.4	1.1	0.6	-0.2	0.7	1.1	0.8	1.3	1.0	1.3	1.3
Illnesses of father: Heart disease	1.6	2.2	6.0	-2.1	2.4	-1.7	-2.0	-1.6	-0.1	0.4	-2.1	1.8	-1.0	-1.1	-0.1	0.9	1.5	-0.6
Illnesses of siblings: Diabetes	0.5	0.6	2.4	-0.8	0.9	0.9	-0.8	-0.2	0.3	-0.7	-1.4	-0.3	0.2	-1.6	0.4	0.6	0.3	0.2
Smoking status: Previous	0.6	0.9	4.8	0.1	0.2	0.2	-0.3	-0.4	-0.8	-1.2	0.1	-0.1	-0.8	-1.3	-0.7	-2.2	-1.4	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	5.6	-0.7	1.4	-0.1	0.0	-0.1	0.5	2.4	-0.9	1.2	0.5	-1.0	0.7	1.6	1.8	0.7
Whole body fat-free mass	0.4	2.1	4.5	0.6	-1.3	1.1	1.6	2.1	1.6	1.3	1.1	-1.7	1.8	1.2	1.6	1.4	1.0	1.7
Leg fat-free mass (right)	0.5	2.5	6.1	0.8	-1.7	2.1	1.9	2.4	1.4	0.3	1.5	-2.5	1.5	1.7	1.3	0.8	0.6	1.3
Arm fat percentage (left)	1.2	4.7	11.3	2.6	-2.9	3.4	3.1	2.2	0.9	-1.4	2.7	-2.7	0.3	3.1	0.7	-1.2	-0.7	0.4
Average weekly red wine intake	0.6	0.8	6.0	0.5	-1.0	1.4	0.3	2.4	0.0	0.9	0.8	-0.4	0.6	0.6	0.0	-0.7	0.2	0.4
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.9	-0.5	0.6	1.4	-0.7	0.5	0.1	0.1	-0.6	-0.2	0.9	-0.6	0.1	1.1	0.9	0.6
Mood swings	0.5	0.9	2.6	-1.4	1.2	-1.2	-1.0	-1.6	-0.4	-1.0	-0.8	-0.2	-0.8	-1.1	-0.3	-0.4	-0.3	-0.8
Loneliness, isolation	1.4	1.9	5.3	-1.0	-0.2	-1.6	-1.0	-2.0	-1.2	-2.3	-0.4	-0.1	-1.7	-0.9	-1.4	-1.2	-1.7	-1.7
Long-standing illness, disability or infirmity	2.0	3.1	7.1	-1.9	1.9	-1.6	-2.7	-1.2	-1.4	-0.3	-2.1	2.2	-2.0	-2.7	-1.2	-0.6	-0.6	-1.9
Ever had bowel cancer screening	1.3	1.5	7.5	-1.4	2.7	-0.0	-1.1	-1.6	0.4	-1.2	-2.1	0.6	-1.2	-1.1	0.3	0.1	0.6	-0.8
Diabetes diagnosed by doctor	0.4	0.7	2.5	1.0	0.1	-0.9	0.1	-1.6	-0.8	0.2	0.8	0.1	-1.0	0.1	-0.9	-0.8	-1.2	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	1.5	0.3	0.1	0.1	0.3	-0.5	-0.9	0.3	0.5	1.2	0.2	0.1	-0.9	-0.1	0.2	-0.2
Friendships satisfaction	4.2	5.3	13.6	3.3	-2.4	1.8	3.7	-0.0	2.0	-0.1	3.3	-2.6	2.3	2.8	1.9	0.7	1.1	2.3
Qualifications: nursing, teaching	0.3	0.5	1.4	0.7	-0.9	1.2	0.9	0.7	-0.6	0.8	0.3	-0.8	-0.5	0.7	-0.4	0.3	-0.3	-0.4
Commuting to job workplace: Walk	0.4	0.4	2.3	-1.5	0.4	-0.4	-1.0	-0.2	0.1	-0.5	-1.2	0.8	0.2	-0.3	-0.1	-0.2	-0.3	-0.1
Eye problems/disorders: Cataract	0.5	0.5	3.6	-0.2	-0.0	-1.9	-0.6	-1.5	0.5	0.4	-0.4	-0.3	-0.1	-0.4	0.4	-0.4	-0.7	0.0
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	4.8	-1.5	1.3	-0.4	-1.5	-1.5	1.1	0.2	-2.2	0.6	1.0	-1.8	1.4	1.8	1.3	1.0
Medication for cholesterol	0.7	1.1	5.7	-0.7	0.3	-1.1	-0.9	0.9	-0.7	-1.1	-0.5	0.8	0.0	-1.5	-0.9	-2.4	-0.7	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	4.4	1.3	-0.7	-0.2	0.5	-1.3	0.6	0.8	1.5	-1.2	-0.6	1.0	0.9	2.1	0.3	-0.0
Back pain experienced in last month	0.9	1.3	9.8	-0.3	0.8	-1.6	-0.4	-3.1	1.0	0.9	-0.8	0.3	0.6	-0.5	1.1	1.0	0.3	0.7
Mineral and other dietary supplements	0.9	1.2	4.2	-1.3	0.7	-0.6	-1.6	0.7	-1.2	-0.2	-1.5	1.1	-0.6	-2.0	-1.1	-0.9	-0.7	-0.8
Breast cancer (self-reported)	0.7	0.8	2.9	-0.2	1.0	-0.1	0.4	-1.5	-1.6	0.6	0.2	-1.7	-0.4	-0.2	-1.4	0.1	0.7	-0.5
Asthma (self-reported)	0.7	1.5	7.4	-0.0	-1.1	-1.2	0.2	-0.5	1.1	-0.5	0.4	1.2	1.4	1.0	1.1	2.7	1.4	1.4
Osteoporosis (self-reported)	0.4	0.5	2.3	-0.7	-0.1	-0.8	-0.7	1.4	-0.1	0.4	-0.4	1.5	-0.1	0.4	-0.1	0.9	0.6	-0.1
Osteoarthritis (self-reported)	0.9	1.2	4.2	-2.1	1.2	-0.8	-2.0	1.1	0.0	-0.1	-2.0	0.9	0.0	-0.7	0.1	0.3	0.8	-0.1
Medication: Aspirin	0.5	0.6	2.7	0.0	1.0	-0.1	-0.8	-0.1	-1.2	-0.1	-0.1	1.6	-1.1	-0.2	-1.2	-0.3	-0.2	-1.0
Medication: Gliclazide	1.6	1.8	5.4	0.2	-0.5	0.1	0.7	-0.7	-2.3	0.1	0.7	-1.4	-1.8	1.4	-2.3	-1.5	-1.2	-2.0
Illnesses of father: None of the above (group 1)	1.1	1.3	4.0	1.8	-1.2	1.2	2.0	0.7	-0.0	-0.2	2.0	-1.1	0.7	0.8	-0.1	-1.1	-1.5	0.2
Smoking status: Current	0.3	0.5	1.4	1.1	-1.1	-0.6	0.5	-0.7	-0.1	0.6	0.8	0.2	0.1	0.7	-0.2	-1.0	-1.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.5	5.3	19.2	3.4	-1.7	1.2	4.4	-0.6	1.0	0.9	4.1	-3.1	1.6	2.6	1.0	1.2	0.7	1.7
Whole body water mass	0.4	2.1	4.7	0.7	-1.4	1.1	1.7	2.2	1.4	1.1	1.3	-1.8	1.8	1.4	1.4	1.3	0.9	1.6
Leg predicted mass (right)	0.5	2.6	6.4	0.9	-1.8	2.1	2.0	2.5	1.4	0.2	1.6	-2.5	1.5	1.7	1.3	0.7	0.6	1.2
Arm fat mass (left)	1.0	4.0	8.8	2.4	-2.6	2.7	3.0	1.8	1.5	-0.8	2.5	-2.5	1.0	2.9	1.4	-0.2	0.0	1.1
Number of self-reported non-cancer illnesses	0.6	1.0	4.7	-1.1	0.8	-1.4	-1.2	-1.0	-0.8	-0.1	-1.0	2.2	-0.3	-1.1	-0.5	0.8	0.8	-0.4
Average weekly champagne plus white wine intake	0.4	0.5	2.5	-0.4	0.0	-1.1	-0.3	0.3	-0.9	-1.6	-0.5	-0.5	-0.9	0.2	-1.0	-0.2	-0.1	-1.0
Miserableness	1.1	1.9	4.6	-2.1	0.9	-1.5	-1.9	-1.0	-1.3	-1.0	-1.7	1.8	-0.7	-1.5	-1.3	-0.7	-0.8	-1.2
Guilty feelings	0.2	0.3	3.1	0.1	-0.5	0.4	0.0	-0.5	-0.1	-1.7	0.5	-0.5	0.3	0.3	-0.1	-0.6	-0.1	0.1
Wears glasses or contact lenses	0.8	1.0	8.4	0.7	0.5	-0.9	0.7	-2.9	0.9	0.5	0.9	-0.2	0.4	0.3	0.9	0.7	0.0	0.7
Ever taken oral contraceptive pill	0.7	0.8	2.1	0.3	0.3	0.2	1.4	-0.4	-1.3	-1.2	1.4	0.1	-0.3	0.0	-1.4	-0.9	-0.9	-0.8
Hearing aid user	1.8	2.1	4.2	-2.1	0.4	-1.3	-1.4	1.3	-1.9	1.3	-2.0	1.1	-1.6	-1.4	-1.7	-0.6	-0.8	-1.7
Mother’s age at death	1.6	2.0	5.1	1.3	-2.3	1.1	1.9	1.9	1.6	0.7	1.8	-0.8	1.1	1.8	1.3	0.3	-0.4	1.0
Financial situation satisfaction	1.0	1.2	4.7	1.4	-0.4	0.1	1.7	-2.2	1.1	0.3	1.3	-1.6	0.0	0.9	1.1	-0.5	0.1	0.2
Tinnitus: Yes, now most or all of the time	0.5	0.5	2.8	-0.8	0.5	-1.7	-0.9	-0.8	0.1	0.3	-1.2	0.2	-0.6	-0.8	0.2	0.4	0.1	-0.4
Commuting to job workplace: Public transport	0.6	0.7	2.6	-0.3	1.0	-0.3	-0.2	0.5	0.7	-1.2	-0.5	1.6	0.8	-0.4	0.6	1.1	0.9	0.7
Eye problems/disorders: Glaucoma	1.3	1.5	5.1	1.2	-1.1	-0.1	1.2	1.0	-2.0	0.3	2.2	-0.6	-0.8	-0.1	-2.0	-0.9	-1.2	-1.1
Medication: Blood pressure	0.6	1.1	6.6	-0.1	0.6	-1.2	-0.6	-1.3	0.7	1.0	-0.7	1.6	-0.7	0.3	0.9	2.6	0.9	0.0
Pain type(s) experienced in last month: Hip pain	1.1	1.4	6.0	-1.1	0.6	-1.8	-1.4	-2.4	-1.0	0.4	-1.2	0.8	-1.0	-1.5	-0.7	-0.7	-0.1	-1.0
Supplements: Fish oil (including cod liver oil)	1.2	1.6	6.1	1.3	-0.8	1.5	2.1	-0.8	0.7	0.6	1.5	-1.7	0.5	2.5	0.7	0.3	0.7	0.6
High cholesterol (Self-reported)	0.5	0.9	3.5	-0.4	1.9	0.1	-0.1	-1.1	-0.6	-0.9	-0.0	0.3	-1.1	-1.8	-0.6	-0.9	-0.7	-1.2
Medication: Bendroflumethiazide	1.7	2.7	7.3	-1.1	2.4	-0.9	-2.1	-0.9	-1.8	-0.4	-1.7	1.4	-2.7	-1.8	-1.6	-0.2	-0.5	-2.3
Medication: Paracetamol	0.4	0.5	4.3	-0.3	-0.1	-0.5	0.3	-0.6	0.5	-0.6	-0.0	-2.1	1.0	-0.8	0.4	-0.6	-0.6	0.4
Medication: Lisinopril	1.0	1.2	4.8	-0.5	1.0	-0.9	-1.1	-0.6	1.5	0.8	-0.9	2.2	-0.0	-0.4	1.4	1.7	1.2	0.5
Medication: Atorvastatin	0.8	1.0	2.2	0.1	1.3	-0.2	-0.5	0.0	-1.3	-0.8	-0.3	1.2	-1.5	-1.2	-1.3	-0.5	-1.3	-1.5
Illnesses of father: High blood pressure	1.3	1.6	5.1	-1.2	1.3	-2.1	-2.0	-2.3	-0.7	-0.8	-1.0	1.0	-0.9	-1.7	-0.5	0.3	0.3	-0.8
Alcohol drinker status: Never	1.3	1.6	7.9	-0.9	0.1	-1.1	-0.8	-0.5	0.8	1.9	-1.1	1.9	0.6	0.4	1.0	2.8	1.5	0.8
Ever smoked	0.5	0.9	3.8	1.3	-1.5	0.1	0.7	0.4	0.5	-0.6	1.1	-0.1	0.5	0.3	0.3	-1.9	-1.8	0.3
Basal metabolic rate	0.5	2.6	4.6	1.0	-1.7	1.4	2.0	2.1	1.7	1.0	1.5	-2.0	1.9	1.7	1.7	1.3	0.9	1.8
Leg fat percentage (left)	0.5	1.9	4.6	1.8	-2.1	1.6	1.8	1.2	1.5	-0.8	1.4	-1.6	0.2	1.8	1.4	-0.2	-0.8	0.5
Arm fat-free mass (left)	0.4	2.2	3.8	1.1	-1.6	0.7	1.8	1.6	1.8	1.3	1.3	-1.5	1.9	1.4	1.7	1.4	0.9	1.9
Number of operations (self-reported)	1.0	1.5	4.9	-0.4	1.4	-0.8	-0.7	-1.6	-0.8	-1.5	-0.5	0.0	-1.1	-1.3	-0.9	-2.2	-1.8	-1.2
Average weekly beer plus cider intake	0.4	0.6	1.4	-0.7	0.7	-1.1	-1.1	-1.1	-1.1	0.4	-0.5	1.2	0.0	-0.8	-1.0	0.1	-0.6	-0.3
Irritability	0.3	0.4	1.5	-0.5	0.5	0.9	0.4	-1.0	-0.1	-1.2	-0.1	-1.0	-0.1	-0.5	-0.1	-1.0	0.2	-0.3
Risk taking	0.8	1.2	3.1	-1.5	0.5	-0.2	-1.8	0.5	-1.0	-0.7	-1.3	0.6	-1.3	-0.7	-1.1	-1.6	-0.5	-1.3
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.5	-1.3	1.1	-0.4	-0.3	-1.6	0.1	-1.4	-1.2	-0.4	0.4	0.4	0.1	-0.6	0.7	0.3
Fractured/broken bones in last 5 years	0.2	0.3	1.7	-0.3	-0.5	-0.5	0.2	0.5	0.1	-1.3	0.1	0.8	0.0	-0.2	-0.0	-0.0	-0.8	-0.1
Age started oral contraceptive pill	0.5	0.6	1.6	0.9	-0.6	0.8	0.4	1.2	-0.2	0.0	1.0	-0.1	-1.3	0.9	-0.3	-0.3	-1.1	-0.9
Diastolic blood pressure, automated reading	0.6	1.9	6.7	-0.3	1.4	-1.2	-0.7	-0.1	-0.4	0.9	-0.8	2.0	-2.6	1.8	-0.1	2.1	1.7	-1.4
Ever depressed for a whole week	0.3	0.4	2.2	-0.7	0.6	-0.1	-0.4	-1.5	-0.3	-0.2	-0.5	0.9	-0.6	-0.7	-0.2	0.8	0.5	-0.4
Unable to work because of sickness or disability	1.2	1.5	3.2	-0.8	0.5	-1.8	-0.9	-1.5	-1.1	-1.6	-0.9	1.4	-1.2	-1.6	-1.0	-0.6	-1.5	-1.4
Commuting to job workplace: Cycle	0.3	0.3	1.1	-0.3	-0.1	-0.8	-0.3	1.0	-0.0	-0.5	-0.6	-0.5	-0.5	-1.1	-0.1	0.0	-0.5	-0.4
Myopia	0.6	0.9	3.9	-1.1	1.5	-0.2	0.2	-2.0	0.6	-1.4	-0.5	0.8	1.1	-0.5	0.3	0.8	0.7	0.9
Vascular/heart problems diagnosed by doctor	1.7	4.6	15.2	1.6	-2.2	2.9	2.9	1.7	0.6	-0.8	2.7	-3.9	2.5	1.0	0.2	-2.7	-1.4	1.5
Cholesterol lowering medication	0.2	0.2	1.1	-0.4	1.0	0.4	-0.1	-0.2	0.4	0.8	-0.1	0.7	-0.4	-0.4	0.4	0.7	0.2	-0.2
Medication: Omeprazole (e.g. Zanprol)	1.7	2.0	7.9	-1.3	1.9	-1.5	-2.2	-0.1	0.8	0.4	-2.4	2.8	-0.4	-1.3	1.0	0.7	0.4	-0.1
Pain experienced in last month	0.2	0.4	2.1	0.7	-0.0	0.1	0.2	1.5	0.3	-0.1	0.9	0.4	-0.4	0.9	0.2	0.4	0.6	-0.1
Supplements: Calcium	0.8	0.9	3.8	-0.5	-0.9	-0.4	-0.7	1.4	-0.9	-1.1	-0.3	-0.5	-0.5	0.1	-0.9	-1.9	-1.0	-0.8
Basal cell carcinoma (self-reported)	0.8	1.0	4.2	-0.4	1.3	-0.5	-0.5	-2.1	1.1	-0.3	-0.3	1.4	1.1	-1.3	1.0	0.2	0.2	0.9
Heart attack/myocardial infarction (self-reported)	0.8	1.0	2.9	1.3	-0.4	1.2	0.1	-0.9	-1.0	-1.4	1.2	0.1	-1.2	-0.0	-1.1	-0.1	-1.7	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.2	0.8	-0.1	0.4	1.0	-0.7	1.1	-0.7	0.6	0.0	0.5	0.5	0.8	-0.2	-0.1	0.6
Heart disease (siblings)	0.4	0.5	1.1	0.7	-0.9	0.7	0.6	0.8	-0.5	-0.8	1.1	0.1	-0.9	0.2	-0.5	-0.9	-1.0	-0.8
Alcohol drinker status: Previous	1.6	1.8	6.1	0.5	-0.3	-1.1	0.0	-0.5	-1.8	-1.7	0.3	0.1	-2.1	-0.4	-1.8	-1.0	-2.5	-2.1
Pack years of smoking	1.5	2.2	6.2	-0.2	0.0	-0.3	-0.5	0.3	-2.2	-1.5	-0.4	0.5	-2.4	-0.3	-2.4	-1.3	-2.3	-2.5
Impedance of whole body	0.1	0.4	3.1	0.7	0.7	-0.1	-0.3	-1.1	-0.1	-0.5	-0.6	1.8	-0.3	-0.2	0.0	0.5	-0.3	0.0
Leg fat mass (left)	0.7	2.9	5.7	1.9	-2.2	2.2	2.4	1.4	1.9	-0.5	1.9	-2.1	0.9	2.1	1.8	0.3	-0.2	1.1
Arm predicted mass (left)	0.4	2.2	3.5	1.1	-1.7	0.7	1.9	1.5	1.6	1.2	1.5	-1.6	1.9	1.5	1.6	1.3	0.7	1.7