Best TWAS P=1.43e-39 · Best GWAS P=1.3e-41 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | CPEB4 | 0.39 | 0.00 | lasso | 6 | 0.03 | 5.0e-02 | 8.0 | -7.6 | 2.3e-14 | -0.67 | 0.04 | 0.61 | FALSE |
| 2 | METSIM | Adipose | CPEB4 | 0.07 | 0.03 | bslmm | 661 | 0.04 | 3.1e-06 | 8.4 | 9.0 | 2.5e-19 | 0.63 | 0.01 | 0.99 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CPEB4 | 0.10 | 0.07 | lasso | 2 | 0.06 | 1.3e-08 | 13.5 | -13.0 | 2.2e-38 | -0.97 | 0.00 | 1.00 | FALSE |
| 4 | YFS | Blood | CPEB4 | 0.58 | 0.72 | bslmm | 632 | 0.73 | 0.0e+00 | 13.5 | 13.2 | 1.4e-39 | 0.99 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C5orf47 | 0.08 | 0.00 | blup | 42 | 0.01 | 1.2e-02 | -6.0 | 7.0 | 1.9e-12 | 0.46 | 0.00 | 0.14 | FALSE |