[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr5:175,662,866-177,260,129

Best TWAS P=6.57e-26 · Best GWAS P=5.94e-31 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RAB24 0.14 0.06 enet 14 0.09 4.2e-11 9.19 10.5 6.6e-26 0.57 0.80 0.20 TRUE
2 GTEx Adipose Subcutaneous RAB24 0.17 0.08 enet 26 0.14 1.7e-11 9.35 6.6 4.8e-11 0.31 0.28 0.72 FALSE
3 GTEx Artery Tibial RAB24 0.18 0.09 lasso 3 0.07 2.3e-06 9.35 7.7 1.4e-14 0.52 0.06 0.94 FALSE
4 GTEx Cells EBV-transformed lymphocytes RAB24 0.37 0.26 lasso 6 0.24 1.7e-08 -6.10 6.5 6.1e-11 0.35 0.94 0.03 FALSE
5 GTEx Colon Transverse MXD3 0.22 0.09 lasso 5 0.13 8.2e-07 -6.10 -5.2 2.2e-07 -0.32 0.97 0.00 FALSE
6 GTEx Esophagus Mucosa UIMC1 0.08 0.00 lasso 5 0.00 3.5e-01 -8.42 -9.1 9.7e-20 -0.42 0.13 0.03 FALSE
7 GTEx Esophagus Mucosa FGFR4 0.18 0.16 enet 8 0.16 9.2e-11 -8.40 -7.5 6.1e-14 -0.35 1.00 0.00 TRUE
8 GTEx Nerve Tibial FGFR4 0.44 0.48 lasso 7 0.47 2.1e-37 -8.40 -8.4 5.3e-17 -0.39 1.00 0.00 FALSE
9 GTEx Pituitary FGFR4 0.30 0.21 lasso 3 0.11 1.0e-03 -6.42 -7.2 7.3e-13 -0.47 0.11 0.17 TRUE
10 GTEx Skin Not Sun Exposed Suprapubic FGFR4 0.19 0.11 lasso 5 0.11 8.3e-07 -8.40 -6.9 4.2e-12 -0.39 0.91 0.00 FALSE
11 GTEx Stomach MXD3 0.21 0.03 lasso 7 0.08 1.4e-04 -6.06 -5.9 4.6e-09 -0.26 0.56 0.02 FALSE
12 GTEx Uterus MXD3 0.51 0.10 enet 30 0.24 1.1e-05 0.39 -5.4 8.5e-08 -0.11 0.08 0.10 FALSE
13 METSIM Adipose RAB24 0.05 0.02 lasso 4 0.02 1.2e-03 9.19 9.6 1.3e-21 0.60 0.15 0.72 TRUE
14 ROSMAP Brain Pre-frontal Cortex FGFR4 0.26 0.14 lasso 20 0.21 4.5e-26 -6.42 -5.1 3.1e-07 -0.42 1.00 0.00 FALSE
15 ROSMAP Brain Pre-frontal Cortex PRELID1 0.05 0.05 enet 10 0.05 1.8e-07 -5.93 6.2 7.6e-10 0.31 1.00 0.00 FALSE
16 The Cancer Genome Atlas Breast Invasive Carcinoma MXD3 0.02 0.02 enet 4 0.02 1.8e-04 -5.97 -6.0 1.9e-09 -0.32 0.83 0.00 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma MXD3 0.04 0.02 lasso 3 0.02 2.9e-03 -5.51 -6.3 3.1e-10 -0.34 0.04 0.20 FALSE
18 The Cancer Genome Atlas Lung Adenocarcinoma MXD3 0.04 0.02 blup 41 0.02 5.6e-04 -5.51 -6.5 8.9e-11 -0.30 0.25 0.04 FALSE
19 The Cancer Genome Atlas Prostate Adenocarcinoma FGFR4 0.11 0.04 enet 19 0.06 8.7e-07 -6.74 6.0 1.6e-09 0.42 0.94 0.02 TRUE
20 The Cancer Genome Atlas Prostate Adenocarcinoma MXD3 0.04 0.02 blup 40 0.03 2.8e-04 -3.78 -5.2 1.6e-07 -0.20 0.42 0.02 TRUE
21 The Cancer Genome Atlas Prostate Adenocarcinoma RAB24 0.23 0.04 enet 19 0.06 6.5e-07 9.19 6.7 1.7e-11 0.27 0.00 0.98 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma MXD3 0.05 0.04 lasso 5 0.04 1.8e-04 -5.96 -6.0 1.7e-09 -0.29 0.61 0.02 FALSE