Best TWAS P=2.75e-08 · Best GWAS P=1.65e-08 conditioned to 0.0075
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | E2F3 | 0.05 | 0.00 | bslmm | 538 | 0.01 | 3.0e-02 | -2.2 | -5.6 | 2.8e-08 | 0.65 | 0.05 | 0.69 | TRUE |
2 | GTEx | Thyroid | CDKAL1 | 0.10 | 0.07 | lasso | 4 | 0.08 | 1.9e-06 | -4.7 | 5.3 | 1.1e-07 | -0.95 | 0.01 | 0.99 | FALSE |