Best TWAS P=1.28e-07 · Best GWAS P=7.4e-07 conditioned to 0.00582
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Frontal Cortex BA9 | KIAA1875 | 0.16 | 0.00 | lasso | 4 | 0.03 | 5.9e-02 | 3.9 | 5.3 | 1.3e-07 | 0.39 | 0.02 | 0.14 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | MAF1 | 0.06 | 0.04 | blup | 81 | 0.05 | 6.4e-07 | -4.5 | -5.1 | 2.7e-07 | -0.25 | 0.01 | 0.93 | TRUE |