[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr9:93,284,804-96,338,382

Best TWAS P=6.7e-19 · Best GWAS P=1.47e-19 conditioned to 0.0151

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	AUH	0.14	0.06	enet	15	0.11	1.2e-13	2.2	5.7	1.2e-08	-0.02	0.06	0.94	TRUE
2	CommonMind	Brain Pre-frontal Cortex	BICD2	0.06	0.04	blup	424	0.04	6.9e-06	7.3	7.0	2.2e-12	0.86	0.07	0.93	FALSE
3	GTEx	Artery Aorta	ECM2	0.11	0.10	lasso	10	0.09	1.1e-05	6.0	6.5	7.1e-11	0.79	0.30	0.69	FALSE
4	GTEx	Artery Aorta	NOL8	0.09	0.04	lasso	9	0.02	2.3e-02	-6.1	5.6	1.9e-08	0.30	0.65	0.02	FALSE
5	GTEx	Artery Tibial	NOL8	0.04	0.03	lasso	4	0.03	3.5e-03	-6.5	6.4	2.0e-10	0.36	0.49	0.02	FALSE
6	GTEx	Brain Caudate basal ganglia	OGN	0.15	-0.01	enet	18	0.02	7.7e-02	-2.8	-7.3	3.1e-13	-0.56	0.04	0.61	FALSE
7	GTEx	Brain Cerebellar Hemisphere	IPPK	0.17	0.22	lasso	13	0.16	6.8e-05	-6.4	-5.9	3.0e-09	-0.31	0.68	0.02	FALSE
8	GTEx	Brain Cerebellar Hemisphere	BICD2	0.27	0.06	lasso	9	0.04	3.9e-02	6.0	5.8	5.0e-09	0.71	0.08	0.37	FALSE
9	GTEx	Brain Cerebellum	ZNF484	0.21	0.01	lasso	9	0.01	1.7e-01	6.3	7.0	2.6e-12	0.79	0.08	0.29	FALSE
10	GTEx	Cells Transformed fibroblasts	OGN	0.03	0.03	lasso	2	0.01	3.2e-02	-6.1	-6.1	8.2e-10	-0.33	0.62	0.03	FALSE
11	GTEx	Esophagus Mucosa	CENPP	0.09	0.01	lasso	5	0.02	2.1e-02	6.0	-6.4	1.2e-10	-0.74	0.17	0.65	FALSE
12	GTEx	Esophagus Muscularis	OGN	0.07	0.03	enet	13	0.02	2.0e-02	-3.1	-5.3	9.5e-08	-0.23	0.47	0.04	FALSE
13	GTEx	Heart Left Ventricle	ECM2	0.07	0.05	lasso	3	0.02	3.1e-02	7.4	6.6	3.7e-11	0.75	0.06	0.77	FALSE
14	GTEx	Liver	ECM2	0.16	0.18	enet	8	0.18	7.4e-06	-6.0	6.2	5.7e-10	0.34	0.85	0.02	FALSE
15	GTEx	Lung	CENPP	0.30	0.24	lasso	8	0.27	1.1e-20	-3.9	-5.3	1.5e-07	-0.41	1.00	0.00	FALSE
16	GTEx	Lung	NOL8	0.08	0.03	enet	15	0.04	2.3e-04	-5.5	5.2	1.9e-07	0.29	0.88	0.00	FALSE
17	GTEx	Muscle Skeletal	OGN	0.03	0.02	enet	9	0.03	3.0e-04	-6.4	-6.2	4.9e-10	-0.36	0.62	0.03	FALSE
18	GTEx	Nerve Tibial	OGN	0.08	0.14	lasso	9	0.12	6.3e-09	-6.6	-6.6	4.6e-11	-0.37	1.00	0.00	FALSE
19	GTEx	Nerve Tibial	ECM2	0.08	0.02	lasso	5	0.01	1.1e-01	5.9	6.1	1.2e-09	0.71	0.09	0.48	FALSE
20	GTEx	Nerve Tibial	NOL8	0.10	0.02	enet	7	0.03	4.7e-03	-5.8	5.9	2.8e-09	0.32	0.71	0.04	FALSE
21	GTEx	Pituitary	IPPK	0.16	0.07	lasso	4	0.07	8.5e-03	-5.9	-8.0	9.0e-16	-0.59	0.11	0.51	FALSE
22	GTEx	Skin Not Sun Exposed Suprapubic	CENPP	0.23	0.09	lasso	11	0.07	9.6e-05	7.0	-6.1	1.3e-09	-0.62	0.69	0.14	FALSE
23	GTEx	Skin Sun Exposed Lower leg	IPPK	0.17	0.07	enet	8	0.07	2.7e-06	9.0	-7.8	8.0e-15	-0.90	0.01	0.99	FALSE
24	GTEx	Skin Sun Exposed Lower leg	CENPP	0.20	0.06	lasso	9	0.14	2.9e-11	7.1	-7.0	2.6e-12	-0.63	0.93	0.07	FALSE
25	GTEx	Small Intestine Terminal Ileum	CENPP	0.29	0.11	enet	11	0.10	2.9e-03	-5.9	-6.2	7.2e-10	-0.46	0.21	0.34	FALSE
26	GTEx	Spleen	BICD2	0.26	0.25	lasso	9	0.24	6.4e-07	6.1	6.1	1.0e-09	0.76	0.53	0.33	FALSE
27	GTEx	Spleen	NOL8	0.29	0.24	lasso	2	0.19	1.1e-05	-7.4	7.3	2.3e-13	0.46	0.64	0.09	FALSE
28	GTEx	Testis	NOL8	0.19	0.24	lasso	11	0.23	1.3e-10	-6.5	6.6	5.6e-11	0.36	1.00	0.00	FALSE
29	GTEx	Whole Blood	BICD2	0.06	0.02	lasso	2	0.01	1.8e-02	6.1	6.1	1.1e-09	0.76	0.08	0.87	FALSE
30	NTR	Blood	CENPP	0.02	0.02	lasso	4	0.02	2.0e-07	-3.9	-5.3	8.9e-08	-0.29	1.00	0.00	FALSE
31	NTR	Blood	IPPK	0.02	0.01	bslmm	416	0.01	9.9e-06	-6.1	-6.2	4.4e-10	-0.42	0.99	0.00	FALSE
32	YFS	Blood	NOL8	0.06	0.09	lasso	17	0.10	1.5e-29	-6.5	6.0	1.7e-09	0.34	1.00	0.00	FALSE
33	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CENPP	0.08	0.00	lasso	6	0.00	1.3e-01	-3.8	-5.9	3.7e-09	-0.49	0.06	0.09	FALSE
34	The Cancer Genome Atlas	Breast Invasive Carcinoma	CENPP	0.07	0.03	lasso	5	0.06	2.1e-11	7.1	-7.9	3.6e-15	-0.69	0.15	0.85	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	OGN	0.02	0.02	lasso	1	0.02	2.7e-04	-6.6	-6.6	5.6e-11	-0.37	0.47	0.35	FALSE
36	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	IPPK	0.06	0.03	blup	49	0.04	5.8e-03	8.6	-6.9	5.1e-12	-0.88	0.01	0.67	FALSE
37	The Cancer Genome Atlas	Colon Adenocarcinoma	CENPP	0.21	0.04	enet	16	0.10	1.9e-06	7.0	-6.8	1.3e-11	-0.62	0.02	0.94	FALSE
38	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CENPP	0.06	0.02	blup	160	0.04	6.3e-05	7.0	-8.2	2.5e-16	-0.72	0.06	0.89	FALSE
39	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	OGN	0.02	0.01	blup	51	0.01	3.4e-02	-7.5	-7.4	1.3e-13	-0.43	0.01	0.84	FALSE
40	The Cancer Genome Atlas	Brain Lower Grade Glioma	AUH	0.05	0.06	lasso	4	0.05	8.5e-07	6.0	5.2	2.4e-07	-0.02	0.46	0.50	FALSE
41	The Cancer Genome Atlas	Brain Lower Grade Glioma	BICD2	0.06	0.02	blup	52	0.05	2.9e-06	7.4	6.1	1.0e-09	0.81	0.04	0.96	FALSE
42	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	OGN	0.07	0.08	lasso	1	0.06	8.0e-04	-6.2	-6.2	6.1e-10	-0.32	0.22	0.15	FALSE
43	The Cancer Genome Atlas	Lung Adenocarcinoma	CENPP	0.14	0.08	lasso	5	0.07	2.9e-08	-3.9	-5.3	1.3e-07	-0.41	1.00	0.00	FALSE
44	The Cancer Genome Atlas	Lung Adenocarcinoma	ECM2	0.10	0.04	lasso	2	0.04	4.2e-05	8.7	8.2	1.8e-16	0.90	0.00	0.99	FALSE
45	The Cancer Genome Atlas	Lung Adenocarcinoma	OGN	0.07	0.12	blup	52	0.14	1.2e-15	-6.2	-6.9	5.1e-12	-0.38	0.94	0.06	FALSE
46	The Cancer Genome Atlas	Lung Adenocarcinoma	OMD	0.04	0.06	lasso	3	0.05	1.1e-06	-6.2	-6.2	6.6e-10	-0.32	0.91	0.06	FALSE
47	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CENPP	0.06	0.04	blup	160	0.05	5.6e-06	7.0	-8.2	1.9e-16	-0.70	0.24	0.70	FALSE
48	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	OGN	0.02	0.02	blup	52	0.02	2.8e-03	7.3	-7.2	5.0e-13	-0.41	0.02	0.94	FALSE
49	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CENPP	0.10	0.01	blup	161	0.04	6.3e-04	-1.3	-6.1	8.4e-10	-0.52	0.22	0.24	FALSE
50	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IPPK	0.03	0.02	blup	51	0.01	3.2e-02	8.7	-6.9	4.2e-12	-0.87	0.03	0.64	FALSE
51	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	OGN	0.05	0.02	blup	52	0.03	2.4e-02	7.3	-7.5	6.5e-14	-0.44	0.02	0.80	FALSE
52	The Cancer Genome Atlas	Stomach Adenocarcinoma	CENPP	0.14	0.03	blup	160	0.04	6.7e-04	7.1	-5.5	3.3e-08	-0.54	0.32	0.28	FALSE
53	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CENPP	0.19	0.09	blup	158	0.08	7.1e-04	7.0	-5.5	3.1e-08	-0.66	0.04	0.45	FALSE
54	The Cancer Genome Atlas	Thyroid Carcinoma	CENPP	0.22	0.15	blup	158	0.19	3.3e-18	-3.6	-5.3	1.5e-07	-0.36	1.00	0.00	FALSE
55	The Cancer Genome Atlas	Thyroid Carcinoma	IPPK	0.03	0.04	blup	50	0.04	6.7e-05	8.6	-8.9	6.7e-19	-0.94	0.01	0.98	TRUE
56	The Cancer Genome Atlas	Thyroid Carcinoma	NOL8	0.02	0.01	blup	38	0.02	7.3e-03	-7.5	7.4	1.6e-13	0.43	0.01	0.86	FALSE