Best TWAS P=1.06e-09 · Best GWAS P=8.64e-09 conditioned to 0.0175
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Adenocarcinoma | COL15A1 | 0.17 | 0.10 | blup | 114 | 0.11 | 9.3e-13 | -4.0 | -5.6 | 2.2e-08 | 0.41 | 0.88 | 0.10 | FALSE |
2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | COL15A1 | 0.18 | 0.06 | blup | 115 | 0.08 | 4.7e-04 | -3.0 | -5.4 | 7.4e-08 | 0.37 | 0.16 | 0.14 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | COL15A1 | 0.05 | 0.04 | enet | 13 | 0.03 | 6.1e-04 | -4.5 | -6.1 | 1.1e-09 | 0.65 | 0.05 | 0.87 | TRUE |
4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | COL15A1 | 0.05 | 0.00 | enet | 7 | 0.02 | 2.0e-02 | -4.0 | -5.8 | 6.7e-09 | 0.61 | 0.04 | 0.67 | FALSE |