[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr9:127,218,258-128,824,378

Best TWAS P=5.58e-12 · Best GWAS P=1.94e-08 conditioned to 5.4e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPP6C 0.03 0.01 bslmm 315 0.01 2.2e-02 -4.8 6.9 5.6e-12 -0.16 0.09 0.23 TRUE
2 GTEx Artery Aorta PRPS1P2 0.08 0.10 lasso 4 0.08 2.1e-05 5.5 -5.7 1.2e-08 0.18 0.05 0.90 FALSE
3 GTEx Artery Tibial GAPVD1 0.11 0.16 enet 19 0.16 6.4e-13 4.8 5.3 9.0e-08 -0.15 0.22 0.78 FALSE
4 GTEx Brain Cerebellum PRPS1P2 0.09 0.08 enet 16 0.04 2.8e-02 4.9 -5.7 1.2e-08 0.16 0.14 0.43 FALSE
5 GTEx Muscle Skeletal PPP6C 0.03 0.03 enet 6 0.01 3.0e-02 -4.9 5.1 2.9e-07 0.02 0.18 0.67 FALSE
6 GTEx Nerve Tibial GAPVD1 0.17 0.08 lasso 10 0.10 9.3e-08 -4.2 5.3 1.2e-07 -0.05 0.19 0.80 FALSE
7 GTEx Nerve Tibial PRPS1P2 0.11 0.11 enet 9 0.10 1.4e-07 -4.8 -5.3 1.1e-07 0.04 0.27 0.72 FALSE
8 GTEx Ovary PRPS1P2 0.14 0.14 lasso 2 0.05 2.9e-02 -4.8 -5.1 3.1e-07 -0.01 0.12 0.40 FALSE
9 GTEx Skin Sun Exposed Lower leg GAPVD1 0.04 0.01 lasso 4 0.01 3.8e-02 -4.6 5.4 5.1e-08 -0.07 0.20 0.69 FALSE
10 GTEx Thyroid GAPVD1 0.05 0.05 enet 13 0.01 6.6e-02 4.8 5.1 2.9e-07 -0.17 0.20 0.77 FALSE
11 GTEx Thyroid PRPS1P2 0.08 0.09 enet 18 0.07 4.0e-06 -4.7 -5.3 1.4e-07 0.01 0.24 0.76 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma WDR38 0.04 0.01 blup 32 0.02 9.5e-04 3.7 5.6 2.2e-08 -0.65 0.02 0.48 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma PPP6C 0.08 0.13 enet 9 0.13 5.5e-13 -4.9 5.1 2.9e-07 0.03 0.02 0.97 FALSE