Best TWAS P=5.49e-16 · Best GWAS P=9.69e-17 conditioned to 0.00927
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Whole Blood | LPAR1 | 0.10 | 0.00 | enet | 23 | 0.00 | 2.3e-01 | -8.3 | -7.8 | 7.7e-15 | 0.71 | 0.01 | 0.98 | TRUE |
2 | METSIM | Adipose | LPAR1 | 0.10 | 0.02 | enet | 26 | 0.06 | 7.4e-09 | -6.2 | -8.1 | 5.5e-16 | 0.64 | 0.02 | 0.98 | TRUE |
3 | NTR | Blood | LPAR1 | 0.19 | 0.07 | lasso | 10 | 0.14 | 2.1e-43 | -8.3 | -7.3 | 2.4e-13 | 0.75 | 0.00 | 1.00 | FALSE |