Best TWAS P=5.01e-12 · Best GWAS P=4.2e-12 conditioned to 0.0623
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | MKX | 0.08 | 0.10 | lasso | 5 | 0.09 | 2.4e-13 | -6.3 | 6.9 | 5.0e-12 | -0.87 | 0.16 | 0.84 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PTCHD3 | 0.08 | 0.05 | lasso | 3 | 0.05 | 8.1e-11 | -5.6 | 5.2 | 1.8e-07 | -0.48 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PTCHD3 | 0.03 | 0.01 | blup | 32 | 0.01 | 2.4e-02 | -5.6 | 5.2 | 1.6e-07 | -0.41 | 0.00 | 0.92 | FALSE |