Best TWAS P=1.53e-08 · Best GWAS P=1.69e-10 conditioned to 0.0185
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | C10orf11 | 0.24 | 0.21 | lasso | 9 | 0.20 | 3.3e-16 | -4.9 | 5.4 | 8.1e-08 | -0.29 | 0.75 | 0.25 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | C10orf11 | 0.40 | 0.32 | enet | 11 | 0.27 | 2.2e-14 | -4.9 | 5.5 | 3.4e-08 | -0.35 | 0.69 | 0.31 | FALSE |
| 3 | GTEx | Lung | C10orf11 | 0.30 | 0.26 | lasso | 5 | 0.24 | 2.0e-18 | -4.9 | 5.3 | 8.9e-08 | -0.28 | 0.79 | 0.21 | TRUE |
| 4 | GTEx | Testis | ZNF503-AS2 | 0.16 | 0.02 | lasso | 4 | 0.06 | 1.3e-03 | -5.1 | -5.1 | 2.9e-07 | 0.43 | 0.08 | 0.41 | FALSE |
| 5 | GTEx | Thyroid | C10orf11 | 0.38 | 0.21 | lasso | 9 | 0.25 | 6.7e-19 | -4.8 | 5.4 | 7.8e-08 | -0.34 | 0.81 | 0.19 | FALSE |
| 6 | ROSMAP | Brain Pre-frontal Cortex | ZNF503-AS2 | 0.07 | 0.06 | lasso | 2 | 0.06 | 2.2e-08 | -5.7 | -5.7 | 1.5e-08 | 0.93 | 0.05 | 0.95 | TRUE |