Best TWAS P=5.1e-11 · Best GWAS P=2.26e-19 conditioned to 2.63e-14
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | ZMIZ1 | 0.36 | 0.26 | enet | 15 | 0.28 | 6.8e-19 | 5.1 | 5.4 | 6.1e-08 | 0.06 | 1.00 | 0.0 | TRUE |
2 | GTEx | Heart Atrial Appendage | ZCCHC24 | 0.19 | 0.01 | lasso | 5 | 0.02 | 3.5e-02 | -5.5 | -6.6 | 5.1e-11 | 0.33 | 0.14 | 0.1 | TRUE |