[Hub]/) : Traits : Ulcerative Colitis :

chr7:106,847,492-108,340,749

Best TWAS P=9.87e-16 · Best GWAS P=1.69e-15 conditioned to 0.00924

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DLD 0.17 0.14 bslmm 510 0.16 1.5e-18 -7.2 -7.1 1.5e-12 0.78 0.48 0.52 FALSE
2 GTEx Brain Cerebellar Hemisphere DLD 0.24 0.06 enet 16 0.05 1.7e-02 6.4 -7.6 3.3e-14 0.78 0.03 0.91 FALSE
3 GTEx Brain Frontal Cortex BA9 DLD 0.21 0.13 lasso 4 0.13 2.8e-04 -6.6 -7.1 1.2e-12 0.76 0.05 0.79 FALSE
4 GTEx Brain Hypothalamus DLD 0.31 0.04 enet 10 0.04 4.6e-02 7.1 -7.5 6.7e-14 0.61 0.12 0.60 FALSE
5 GTEx Cells Transformed fibroblasts CTB-13F3.1 0.10 0.04 enet 14 0.04 3.2e-04 -7.0 -5.3 1.0e-07 0.66 0.06 0.88 FALSE
6 GTEx Testis DLD 0.11 0.12 lasso 2 0.06 1.1e-03 -7.3 -6.9 4.2e-12 0.82 0.08 0.69 FALSE
7 NTR Blood DLD 0.04 0.02 lasso 2 0.02 2.2e-08 -7.2 -7.3 2.5e-13 0.86 0.32 0.68 FALSE
8 ROSMAP Brain Pre-frontal Cortex LAMB1 0.06 0.05 enet 14 0.05 3.3e-07 -7.0 5.6 2.3e-08 -0.77 0.53 0.47 FALSE
9 ROSMAP Brain Pre-frontal Cortex DLD 0.12 0.12 lasso 8 0.15 2.1e-18 7.0 -8.0 9.9e-16 0.80 0.65 0.35 TRUE
10 YFS Blood DLD 0.02 0.01 bslmm 508 0.01 2.3e-04 -7.2 6.3 2.9e-10 -0.82 0.09 0.91 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma DLD 0.05 0.04 blup 64 0.04 2.0e-04 7.6 -6.1 1.4e-09 0.42 0.08 0.79 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma DLD 0.09 0.12 blup 64 0.11 2.5e-12 6.9 -6.6 3.3e-11 0.50 0.67 0.33 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma LAMB1 0.03 0.01 blup 92 0.02 7.7e-03 1.2 -5.2 2.0e-07 0.50 0.04 0.26 FALSE