[Hub]/) : Traits : Ulcerative Colitis : ← →

chr7:127,878,155-129,284,182

Best TWAS P=3.38e-09 · Best GWAS P=2.85e-07 conditioned to 0.472

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum IRF5 0.16 0.08 lasso 4 0.08 8.2e-05 5.1 5.1 2.9e-07 0.99 0.00 0.99 FALSE
2 GTEx Colon Transverse IRF5 0.21 0.22 lasso 4 0.22 8.0e-11 5.1 5.2 1.7e-07 1.00 0.00 1.00 FALSE
3 GTEx Esophagus Mucosa IRF5 0.13 0.14 lasso 4 0.13 4.6e-09 5.1 5.2 1.7e-07 1.00 0.00 1.00 FALSE
4 GTEx Esophagus Muscularis IRF5 0.21 0.12 lasso 5 0.11 3.9e-07 5.1 5.1 2.7e-07 0.95 0.00 1.00 FALSE
5 GTEx Nerve Tibial IRF5 0.13 0.09 enet 10 0.07 1.2e-05 5.1 5.4 5.4e-08 0.95 0.00 1.00 FALSE
6 GTEx Skin Sun Exposed Lower leg IRF5 0.10 0.14 lasso 2 0.12 1.9e-10 5.1 5.2 2.5e-07 1.00 0.00 1.00 FALSE
7 GTEx Whole Blood IRF5 0.17 0.06 lasso 4 0.09 1.2e-08 -4.2 5.2 2.3e-07 0.91 0.00 1.00 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma IRF5 0.10 0.09 lasso 4 0.08 1.6e-16 5.1 5.1 2.6e-07 0.99 0.00 1.00 FALSE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma IRF5 0.09 0.04 lasso 4 0.06 2.3e-04 5.1 5.3 9.0e-08 0.97 0.00 0.99 FALSE
10 The Cancer Genome Atlas Liver Hepatocellular Carcinoma IRF5 0.17 0.09 enet 6 0.15 1.8e-07 -4.2 5.3 1.1e-07 0.81 0.02 0.98 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IRF5 0.09 0.09 blup 30 0.13 3.1e-14 -4.7 5.9 3.4e-09 0.79 0.01 0.98 TRUE
12 The Cancer Genome Atlas Prostate Adenocarcinoma IRF5 0.23 0.26 lasso 3 0.26 3.6e-27 -4.7 5.2 2.1e-07 0.92 0.01 0.99 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma IRF5 0.22 0.21 enet 9 0.26 4.6e-25 -4.7 5.2 2.0e-07 0.92 0.00 1.00 FALSE
14 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma IRF5 0.27 0.16 blup 30 0.22 9.7e-07 -4.7 5.3 1.0e-07 0.71 0.01 0.97 FALSE