[Hub]/) : Traits : Verbal and Numeric Reasoning (VNR) : ← →

chr1:40,799,427-42,542,658

Best TWAS P=1.23e-14 · Best GWAS P=1.65e-14 conditioned to 6.61e-07

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Cells Transformed fibroblasts	FOXO6	0.27	0.16	lasso	6	0.32	1.0e-24	-5.4	-7.7	1.2e-14	0.41	1.00	0.00	TRUE
8	ROSMAP	Brain Pre-frontal Cortex	FOXO6	0.07	0.03	enet	14	0.05	1.5e-06	-5.1	-6.9	6.5e-12	0.35	0.87	0.08	FALSE
5	GTEx	Esophagus Muscularis	SCMH1	0.18	0.03	enet	19	0.10	1.1e-06	2.8	6.1	9.4e-10	-0.51	0.16	0.71	FALSE
1	GTEx	Adrenal Gland	FOXO6	0.39	0.21	lasso	12	0.17	8.1e-07	-5.7	-6.0	2.1e-09	0.38	0.97	0.00	FALSE
3	GTEx	Brain Cerebellum	FOXO6	0.35	0.33	enet	21	0.36	1.2e-11	-5.7	-6.0	2.3e-09	0.46	0.99	0.01	FALSE
6	GTEx	Liver	FOXO6	0.31	0.37	lasso	1	0.37	2.7e-11	-5.7	-5.7	1.5e-08	0.38	1.00	0.00	FALSE
7	METSIM	Adipose	FOXO6	0.10	0.09	lasso	9	0.10	1.9e-14	-5.7	-5.6	2.0e-08	0.39	1.00	0.00	FALSE
2	GTEx	Brain Cerebellar Hemisphere	FOXO6	0.34	0.16	lasso	2	0.17	3.5e-05	-5.1	-5.1	2.8e-07	0.39	0.46	0.31	FALSE