[Hub]/) : Traits : Verbal and Numeric Reasoning (VNR) : ← →

chr1:40,799,427-42,542,658

Best TWAS P=1.23e-14 · Best GWAS P=1.65e-14 conditioned to 6.61e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland FOXO6 0.39 0.21 lasso 12 0.17 8.1e-07 -5.7 -6.0 2.1e-09 0.38 0.97 0.00 FALSE
2 GTEx Brain Cerebellar Hemisphere FOXO6 0.34 0.16 lasso 2 0.17 3.5e-05 -5.1 -5.1 2.8e-07 0.39 0.46 0.31 FALSE
3 GTEx Brain Cerebellum FOXO6 0.35 0.33 enet 21 0.36 1.2e-11 -5.7 -6.0 2.3e-09 0.46 0.99 0.01 FALSE
4 GTEx Cells Transformed fibroblasts FOXO6 0.27 0.16 lasso 6 0.32 1.0e-24 -5.4 -7.7 1.2e-14 0.41 1.00 0.00 TRUE
5 GTEx Esophagus Muscularis SCMH1 0.18 0.03 enet 19 0.10 1.1e-06 2.8 6.1 9.4e-10 -0.51 0.16 0.71 FALSE
6 GTEx Liver FOXO6 0.31 0.37 lasso 1 0.37 2.7e-11 -5.7 -5.7 1.5e-08 0.38 1.00 0.00 FALSE
7 METSIM Adipose FOXO6 0.10 0.09 lasso 9 0.10 1.9e-14 -5.7 -5.6 2.0e-08 0.39 1.00 0.00 FALSE
8 ROSMAP Brain Pre-frontal Cortex FOXO6 0.07 0.03 enet 14 0.05 1.5e-06 -5.1 -6.9 6.5e-12 0.35 0.87 0.08 FALSE