Best TWAS P=4.63e-09 · Best GWAS P=2.26e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FAM160A1 | 0.04 | 0.04 | blup | 436 | 0.06 | 1.8e-07 | -5.9 | 5.8 | 8.3e-09 | -0.88 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | RP11-164P12.3 | 0.13 | 0.03 | lasso | 5 | 0.02 | 4.4e-02 | -4.2 | 5.3 | 1.1e-07 | -0.80 | 0.19 | 0.32 | FALSE |
| 3 | GTEx | Heart Left Ventricle | PET112 | 0.14 | 0.06 | lasso | 4 | 0.04 | 5.0e-03 | -5.9 | 5.9 | 4.6e-09 | -0.99 | 0.03 | 0.89 | TRUE |
| 4 | GTEx | Nerve Tibial | PET112 | 0.13 | 0.10 | enet | 13 | 0.10 | 9.7e-08 | -5.6 | 5.8 | 7.7e-09 | -0.93 | 0.03 | 0.97 | FALSE |
| 5 | GTEx | Nerve Tibial | RP11-164P12.3 | 0.08 | 0.14 | lasso | 6 | 0.14 | 8.3e-10 | -4.9 | 5.4 | 7.9e-08 | -0.90 | 0.06 | 0.94 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | PET112L | 0.13 | 0.08 | lasso | 3 | 0.08 | 1.9e-08 | -4.6 | 5.1 | 3.0e-07 | -0.78 | 0.68 | 0.32 | FALSE |