TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Verbal and Numeric Reasoning (VNR)
:
←
→
chr21:39,856,991-41,390,857
Best TWAS P=2.05e-07 · Best GWAS P=3.91e-05 conditioned to 0.895
39.8M
40M
40.2M
40.4M
40.6M
40.8M
41M
41.2M
41.4M
0
1
2
3
4
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Nerve Tibial
BRWD1
0.17
0.01
lasso
6
0.03
0.0046
-4.1
-5.2
2e-07
0.81
0.01
0.53
TRUE