Best TWAS P=1.57e-07 · Best GWAS P=1.2e-07 conditioned to 0.239
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | METTL13 | 0.23 | 0.23 | bslmm | 479 | 0.27 | 2.0e-33 | 4.9 | 5.2 | 1.6e-07 | 0.92 | 0.01 | 0.99 | TRUE |
2 | GTEx | Brain Cerebellum | METTL13 | 0.22 | 0.00 | enet | 25 | 0.05 | 1.5e-02 | 4.9 | -5.2 | 2.6e-07 | -0.65 | 0.02 | 0.87 | FALSE |
3 | YFS | Blood | METTL13 | 0.11 | 0.10 | bslmm | 482 | 0.10 | 1.5e-32 | 4.9 | -5.2 | 1.8e-07 | -0.92 | 0.02 | 0.98 | FALSE |