Best TWAS P=9.2e-12 · Best GWAS P=3.92e-12 conditioned to 0.886
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | SGCD | 0.26 | 0.09 | enet | 29 | 0.18 | 2.2e-10 | 5.4 | 5.5 | 3.7e-08 | 0.29 | 0.96 | 0.04 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TIMD4 | 0.12 | 0.13 | lasso | 5 | 0.12 | 3.1e-24 | 5.9 | 6.0 | 1.6e-09 | 0.60 | 0.02 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | TIMD4 | 0.26 | 0.18 | lasso | 5 | 0.16 | 1.4e-05 | 5.9 | 5.6 | 2.1e-08 | 0.52 | 0.02 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | TIMD4 | 0.09 | 0.05 | blup | 41 | 0.05 | 1.7e-06 | 5.9 | 6.8 | 9.2e-12 | 0.80 | 0.01 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TIMD4 | 0.28 | 0.26 | lasso | 5 | 0.26 | 7.4e-18 | 5.9 | 6.2 | 5.5e-10 | 0.61 | 0.02 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | TIMD4 | 0.08 | 0.06 | lasso | 4 | 0.04 | 2.1e-03 | 6.1 | 6.4 | 1.5e-10 | 0.98 | 0.00 | 0.97 | FALSE |