Best TWAS P=1.58e-08 · Best GWAS P=3.93e-09 conditioned to 0.22
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Whole Blood | NDST1 | 0.17 | 0.12 | enet | 10 | 0.13 | 9.7e-12 | 5.5 | -5.7 | 1.6e-08 | -0.90 | 0.01 | 0.99 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | CCDC69 | 0.08 | 0.07 | bslmm | 611 | 0.06 | 2.9e-08 | -4.8 | -5.5 | 4.1e-08 | -0.05 | 0.00 | 0.99 | TRUE |
3 | YFS | Blood | NDST1 | 0.34 | 0.27 | lasso | 8 | 0.29 | 2.0e-94 | 5.5 | -5.6 | 2.5e-08 | -0.91 | 0.01 | 0.99 | FALSE |