[Hub]/) : Traits : Blood White Count :

chr5:178,343,081-180,033,292

Best TWAS P=2.62e-19 · Best GWAS P=1.57e-17 conditioned to 0.00618

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C5orf45 0.14 0.18 bslmm 447 0.17 1.1e-20 -6.2 -6.7 1.7e-11 0.25 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex CANX 0.14 0.17 lasso 4 0.17 1.0e-20 8.4 7.8 6.0e-15 -0.90 0.01 0.99 FALSE
3 GTEx Cells Transformed fibroblasts CANX 0.11 0.08 enet 5 0.01 3.4e-02 8.4 8.3 1.3e-16 -0.89 0.01 0.99 FALSE
4 GTEx Cells Transformed fibroblasts TBC1D9B 0.13 0.06 lasso 5 0.09 4.2e-07 4.4 -6.1 1.4e-09 0.30 0.69 0.26 FALSE
5 GTEx Cells Transformed fibroblasts CTC-241N9.1 0.19 0.03 enet 16 0.04 4.4e-04 5.8 -5.7 1.1e-08 0.14 0.95 0.00 FALSE
6 GTEx Esophagus Muscularis CANX 0.11 0.05 enet 3 0.04 1.6e-03 -8.5 8.0 1.9e-15 -0.95 0.00 0.99 FALSE
7 GTEx Nerve Tibial CANX 0.18 0.08 lasso 7 0.07 5.7e-06 7.7 8.8 1.3e-18 -0.83 0.01 0.99 FALSE
8 GTEx Nerve Tibial HNRNPH1 0.11 0.01 enet 15 0.02 8.2e-03 -3.7 5.3 1.1e-07 -0.45 0.07 0.37 FALSE
9 GTEx Nerve Tibial TBC1D9B 0.22 0.08 enet 20 0.25 1.0e-17 4.4 -5.2 2.6e-07 0.30 0.98 0.01 FALSE
10 GTEx Nerve Tibial CTC-241N9.1 0.13 0.10 lasso 5 0.10 1.4e-07 5.8 -6.1 9.4e-10 0.11 0.99 0.00 FALSE
11 GTEx Skin Sun Exposed Lower leg CTC-241N9.1 0.13 0.08 lasso 1 0.05 4.1e-05 5.8 -5.8 8.1e-09 0.06 0.86 0.00 FALSE
12 GTEx Stomach TBC1D9B 0.30 0.00 enet 28 0.07 2.8e-04 4.4 -5.2 2.0e-07 0.31 0.14 0.19 FALSE
13 GTEx Testis CTC-241N9.1 0.14 0.10 enet 8 0.12 8.7e-06 6.1 -5.5 4.7e-08 0.01 0.85 0.01 FALSE
14 GTEx Thyroid CANX 0.08 0.02 enet 11 0.01 2.8e-02 -8.5 6.2 4.2e-10 -0.90 0.00 0.98 FALSE
15 GTEx Thyroid C5orf45 0.09 0.05 lasso 3 0.05 2.1e-04 -6.1 -6.8 9.7e-12 0.30 0.36 0.08 FALSE
16 METSIM Adipose CANX 0.07 0.06 enet 17 0.06 9.3e-10 7.2 5.2 2.0e-07 -0.74 0.04 0.96 FALSE
17 NTR Blood SQSTM1 0.01 0.00 enet 10 0.00 2.2e-02 5.6 -6.3 3.0e-10 0.27 0.52 0.09 FALSE
18 ROSMAP Brain Pre-frontal Cortex SQSTM1 0.09 0.09 lasso 7 0.09 2.9e-11 -5.6 -6.1 1.3e-09 0.23 1.00 0.00 FALSE
19 ROSMAP Brain Pre-frontal Cortex HMGB3P22 0.08 0.04 lasso 5 0.04 2.4e-06 7.7 7.0 1.8e-12 -0.85 0.02 0.98 FALSE
20 YFS Blood CANX 0.07 0.08 enet 21 0.08 1.0e-25 8.4 8.0 1.5e-15 -0.88 0.00 1.00 FALSE
21 YFS Blood SQSTM1 0.07 0.05 bslmm 447 0.09 2.3e-29 6.0 -6.2 6.0e-10 0.38 1.00 0.00 FALSE
22 The Cancer Genome Atlas Colon Adenocarcinoma CANX 0.10 0.02 lasso 4 0.04 1.4e-03 -7.2 7.5 7.1e-14 -0.68 0.01 0.67 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LTC4S 0.04 0.00 blup 39 0.02 2.6e-03 1.1 -9.0 2.6e-19 0.75 0.01 0.65 TRUE
24 The Cancer Genome Atlas Brain Lower Grade Glioma CANX 0.03 0.02 blup 41 0.03 2.0e-04 8.2 7.5 4.5e-14 -0.82 0.01 0.94 FALSE
25 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C5orf45 0.06 0.02 enet 7 0.06 1.3e-04 2.8 -5.8 7.7e-09 0.13 0.20 0.03 FALSE