Best TWAS P=8.5e-08 · Best GWAS P=2.56e-10 conditioned to 0.00073
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | EFHC1 | 0.15 | 0.09 | lasso | 7 | 0.09 | 9.4e-12 | 3.4 | -5.3 | 1.2e-07 | 0.69 | 0.31 | 0.69 | FALSE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PAQR8 | 0.04 | 0.03 | enet | 6 | 0.03 | 6.9e-04 | 4.3 | 5.4 | 8.5e-08 | -0.82 | 0.03 | 0.57 | TRUE |