Hub : Genes

EFHC1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1000	0.0300	4.9e-04	0.047	0.024	0.074	0.065	0.075	2.1e-06	5.1e-04	2.5e-09	2.6e-08	1.9e-09
2	ROSMAP	Brain Pre-frontal Cortex	0.1526	0.0346	3.3e-08	0.085	0.056	0.068	0.071	0.091	4.3e-11	1.1e-07	4.7e-09	1.9e-09	9.4e-12
3	YFS	Blood	0.0386	0.0124	2.3e-04	0.004	0.014	0.017	0.015	0.010	1.5e-02	1.7e-05	2.2e-06	7.2e-06	2.4e-04
4	TCGA	Breast Invasive Carcinoma	0.0166	0.0085	3.3e-03	0.004	0.001	0.001	NA	0.001	4.7e-02	1.6e-01	2.2e-01	NA	1.5e-01
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.0462	0.0219	1.3e-03	0.044	0.011	0.005	NA	0.019	9.0e-06	1.8e-02	8.0e-02	NA	2.6e-03
6	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1270	0.0740	7.0e-03	0.080	0.029	0.046	NA	0.061	2.5e-05	8.7e-03	1.2e-03	NA	2.1e-04
7	TCGA	Brain Lower Grade Glioma	0.0475	0.0285	5.8e-03	0.003	0.018	0.015	NA	0.007	1.3e-01	3.4e-03	7.5e-03	NA	4.9e-02
8	TCGA	Lung Adenocarcinoma	0.0473	0.0262	6.6e-03	-0.001	0.007	0.011	NA	0.003	4.3e-01	4.5e-02	1.5e-02	NA	1.4e-01
9	TCGA	Thyroid Carcinoma	0.0520	0.0250	6.2e-04	0.028	0.037	0.039	NA	0.037	9.4e-04	1.5e-04	1.0e-04	NA	1.5e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.9	1.5	2.5	-0.9	1.4	-0.2	-1.2	-1.2	-1.2	-1.5	-1.0	-1.6
Bipolar Disorder or Schizophrenia	0.5	1.3	3.5	-1.0	0.6	0.0	-1.2	-1.1	-1.1	-1.1	-1.1	-1.9
Depressed Affect (Nagel 2018)	0.5	1.1	2.4	0.8	0.4	0.2	1.5	1.1	1.1	1.0	1.6	0.8
Depression (Nagel 2018)	0.4	0.6	1.9	-0.8	0.1	1.3	-0.1	-0.5	-0.5	0.3	-0.6	-1.4
Intelligence (Savage-Jansen 2018)	0.8	2.4	4.3	1.0	-1.6	0.2	1.9	2.1	2.1	1.6	0.8	1.4
Neuroticism (Nagel 2018)	0.1	0.2	0.6	-0.4	0.8	0.7	-0.0	-0.3	-0.3	-0.5	0.0	-0.5
Schizophrenia (2018)	0.2	0.3	1.3	-0.6	-0.4	0.2	-0.6	-0.5	-0.5	-0.1	-0.6	-1.1
Schizophrenia vs Biploar Disorder	0.5	0.6	2.2	-0.7	-1.5	0.2	0.2	0.9	0.9	0.4	0.5	-0.8
Worry (Nagel 2018)	0.2	0.5	2.1	-1.4	0.1	0.5	-0.6	-0.6	-0.6	-0.7	-0.5	-0.5
Alzheimer’s Disease (in mother)	0.4	0.5	1.3	0.0	0.4	-0.5	-0.9	-1.2	-1.2	-0.4	-0.4	0.2
Alzheimer’s Disease (in father)	1.0	1.1	2.7	1.1	-0.9	0.0	1.1	1.1	1.1	0.7	1.0	1.6
Alzheimer’s Disease (including proxy)	0.1	0.2	0.7	0.6	0.1	-0.0	0.2	-0.1	-0.1	0.5	0.1	0.8
Crohns Disease (2017)	0.7	1.6	2.7	-0.0	-0.4	-1.6	1.6	1.5	1.5	1.2	0.4	1.7
Irritable Bowel Disease (IBD)	0.4	0.9	2.3	-0.3	0.3	-0.3	1.5	1.4	1.4	0.8	0.5	0.5
Ulcerative Colitis (UC)	0.4	0.7	1.6	-0.5	1.1	1.3	1.0	0.9	0.9	-0.3	0.3	-0.8
Major Depression (MDD)	0.3	0.4	0.9	-0.6	-0.2	0.5	0.8	1.0	1.0	0.3	0.7	0.0
Reaction Time	1.5	2.8	7.0	-1.9	-0.7	-0.9	-2.0	-1.2	-1.2	-2.1	-2.6	-1.5
Verbal and Numeric Reasoning (VNR)	0.7	1.8	5.6	-0.1	-2.4	-0.5	1.3	1.4	1.4	1.1	-0.2	1.9
Breast Cancer	0.3	0.6	2.0	1.4	0.9	0.1	0.6	0.0	0.0	0.9	0.6	1.0
Ovarian Cancer	0.9	1.2	3.3	-1.1	0.8	1.8	-0.1	-1.3	-1.3	0.0	-1.3	-0.6
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	4.1	5.9	9.1	-1.8	2.1	1.6	-2.5	-2.9	-2.9	-3.0	-2.3	-2.5
Bipolar Disorder (2011)	4.5	4.3	9.5	-1.4	-0.3	-0.7	-3.1	-2.4	-2.4	-2.0	-2.6	-2.3
Body Mass Index (BMI) (2010)	0.9	1.3	4.7	-0.5	-1.4	-2.2	0.0	0.7	0.7	0.5	-0.4	1.7
Coronary Artery Disease (CAD)	1.0	1.2	2.4	0.2	0.7	0.3	1.5	1.5	1.5	0.8	1.5	0.5
Crohns Disease (2012)	1.2	1.9	3.5	-0.3	-1.5	-1.7	1.3	1.9	1.9	1.2	0.1	1.4
Mean Putamen Volume	0.5	0.6	1.8	-0.9	-1.3	-0.3	-0.3	-0.1	-0.1	-0.8	-1.3	0.4
Fasting Glucose	3.0	3.5	6.6	1.6	-0.0	0.6	2.6	2.5	2.5	2.1	1.9	1.6
HbA1C	0.3	0.3	0.7	-0.0	-0.2	-0.8	-0.8	-0.6	-0.6	-0.4	-0.7	-0.2
HDL Cholesterol	0.2	0.3	1.8	-0.3	0.2	-1.4	-0.0	0.5	0.5	-0.3	0.4	-0.7
LDL Cholesterol	1.0	1.5	6.1	-0.1	-1.6	-2.1	-0.2	-0.0	-0.0	0.5	-0.4	2.5
Lupus	1.0	1.6	5.5	-0.6	-1.6	-2.4	0.8	0.7	0.7	1.1	0.7	1.6
Neuroticism (2016)	1.1	1.6	3.7	-0.2	1.9	-0.3	-1.5	-1.7	-1.7	-1.6	-0.2	-0.6
Primary Biliary Cirrhosis	0.4	0.5	1.0	0.4	-0.9	-0.1	0.7	1.0	1.0	0.4	0.8	0.8
Rheumatoid Arthritis	0.5	0.7	1.6	-0.6	1.3	-0.4	1.0	0.3	0.3	1.2	1.3	0.1
Schizophrenia (2014)	1.2	2.7	7.8	-0.7	1.4	1.5	-1.6	-1.8	-1.8	-1.6	-0.9	-2.8
Triglycerides	0.3	0.5	2.6	0.2	-0.8	-1.6	-0.6	-0.5	-0.5	0.3	-0.5	0.6
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.1	-1.0	-0.0	-0.5	-0.7	-0.7	-0.7	-0.2	-0.3	0.6
Ulcerative Colitis	0.4	0.5	1.8	-1.2	0.4	0.7	-0.2	0.3	0.3	-0.8	-0.2	-1.3
Blood Eosinophil Count	1.1	8.3	18.4	0.5	-2.6	-3.6	1.9	1.9	1.9	3.8	3.3	4.3
Blood Platelet Count	1.9	22.0	57.5	-0.9	-4.2	-7.6	3.8	4.3	4.3	5.3	2.2	6.1
Blood Red Count	0.9	8.6	18.5	-1.6	-0.8	-4.3	-4.3	-3.2	-3.2	-2.9	-2.8	-1.2
Blood White Count	1.1	8.4	28.0	-2.5	-5.3	-3.4	1.7	3.2	3.2	1.8	0.5	1.8
Heel T-Score	0.4	3.0	13.0	-0.3	-2.8	-3.6	-0.2	0.5	0.5	1.7	0.7	1.7
BMI	0.3	1.9	8.5	-0.4	-1.9	-2.9	-0.1	1.4	1.4	1.0	0.0	0.0
Height	0.7	13.0	24.8	1.9	4.9	2.9	-3.2	-5.0	-5.0	-4.1	-1.5	-1.5
Waist Hip Ratio (WHR)	0.1	0.6	2.2	0.7	0.7	0.8	-0.4	-0.1	-0.1	-1.5	-0.8	-0.8
Systolic Blood Pressure	0.4	1.8	6.0	-0.4	1.1	-2.5	-1.6	-1.4	-1.4	-0.9	0.9	0.7
Smoking Status	0.1	0.3	0.6	-0.7	0.5	-0.1	0.1	-0.6	-0.6	0.4	0.4	0.8
Allergy or Eczema	0.2	0.6	2.0	0.5	-1.1	1.4	0.7	0.8	0.8	0.3	0.3	0.1
Cardiovascular Disease	0.6	1.9	9.1	0.4	0.3	-3.0	-1.2	-1.3	-1.3	0.5	0.7	1.6
Hypothyroidism (self reported)	0.3	0.7	2.3	1.5	-0.5	-0.6	0.4	0.5	0.5	0.9	1.1	0.6
Respiratory disease	0.6	1.2	3.0	0.8	-1.2	1.1	1.2	1.7	1.7	-0.1	-0.3	0.5
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.4	-0.1	-1.2	0.8	0.6	0.8	0.8	0.9	0.1	0.1
Lung FEV1/FVC ratio	0.5	2.3	16.3	-4.0	-0.3	-0.7	-1.0	-1.1	-1.1	-0.0	-0.1	-0.8
Lung FVC	0.8	4.1	15.2	-2.3	-3.9	-2.8	-1.6	0.1	0.1	0.6	-2.2	-1.2
Neuroticism	0.3	0.6	2.6	0.3	1.4	1.6	0.2	-0.6	-0.6	0.2	0.2	-0.0
Chronotype (morning person)	0.6	1.3	3.5	-1.0	1.4	0.1	-1.1	-1.9	-1.9	0.3	0.3	-0.7
Hair Pigment	0.1	2.2	4.5	0.3	-0.1	0.2	-1.8	-2.1	-2.1	-2.1	-1.8	-0.4
Tanning	0.1	0.9	3.0	0.6	1.2	-1.3	0.3	0.4	0.4	1.7	1.0	-0.3
Hand grip strength (left)	0.2	0.5	1.9	-0.5	-0.2	-1.4	-0.7	0.2	0.2	-1.3	-0.1	-0.6
Number of treatments/medications taken	0.1	0.2	0.8	-0.0	-0.4	-0.9	0.1	0.5	0.5	-0.4	-0.1	0.6
Average weekly spirits intake	0.5	0.6	1.7	-1.0	-0.8	-0.8	0.1	0.7	0.7	-1.3	-0.5	0.5
Sensitivity / hurt feelings	0.8	1.4	2.8	-0.2	1.6	1.0	-1.2	-1.2	-1.2	-1.3	-0.8	-1.7
Frequency of depressed mood in last 2 weeks	0.8	1.1	2.2	-1.2	1.0	0.2	-0.9	-1.5	-1.5	-0.7	-0.4	-1.0
Hearing difficulty/problems: Yes	0.2	0.3	2.0	-1.4	-0.3	0.2	-0.2	-0.1	-0.1	0.3	-0.3	-0.0
Relative age of first facial hair	0.3	0.6	1.8	1.4	0.2	1.3	0.7	0.7	0.7	-0.1	-0.3	0.2
Other serious medical condition/disability diagnosed by doctor	1.5	2.0	7.6	1.4	1.0	2.8	1.4	0.7	0.7	1.6	1.5	0.1
Ever used hormone-replacement therapy (HRT)	2.2	2.7	7.8	1.2	-2.8	-1.4	1.1	1.9	1.9	1.4	0.8	1.6
Ever had hysterectomy (womb removed)	0.5	0.6	1.3	-0.5	-0.3	-0.9	-1.1	-0.4	-0.4	-0.3	-1.2	-1.1
Systolic blood pressure, automated reading	0.9	2.5	8.4	1.9	0.5	-1.0	1.0	0.9	0.9	1.4	2.9	2.1
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	2.5	-0.5	-1.6	-0.9	-0.9	0.2	0.2	0.2	-0.1	-0.8
Angina	0.7	0.9	5.3	-2.3	0.1	-0.3	-0.2	-0.8	-0.8	0.4	-0.4	-1.1
Medication for hormone replacement therapy	0.3	0.4	2.6	-0.0	-0.4	-0.2	0.1	0.1	0.1	-0.5	0.7	1.6
Vitamin and mineral supplements	2.3	3.1	5.9	2.4	-0.4	-0.1	2.4	2.2	2.2	1.3	1.3	1.9
Supplements: Zinc	0.6	0.6	1.8	-0.8	-0.7	-0.1	-0.9	0.2	0.2	-1.3	-1.0	-0.9
Medication: Co-codamol	0.6	0.6	1.6	0.4	-1.2	-0.1	0.7	1.1	1.1	1.1	-0.5	-0.1
Medication: Metformin	0.5	0.7	3.5	-0.7	-1.9	0.4	0.2	0.9	0.9	-0.0	-0.8	-0.4
Diabetes (father)	0.7	0.8	1.8	0.4	-0.9	-0.2	0.9	1.4	1.4	-0.1	0.6	1.2
Diabetes (mother)	0.6	0.8	2.5	-0.9	-1.6	-1.3	-0.1	0.6	0.6	-0.2	-1.0	0.7
Severe depression (siblings)	1.4	1.6	5.8	-2.4	-0.0	-0.6	-1.1	-0.5	-0.5	-1.6	-1.2	-1.6
Pack years adult smoking proportion	0.4	0.6	2.4	-0.8	-0.1	0.8	-0.3	-0.9	-0.9	1.6	-0.2	-0.5
Impedance of leg (right)	1.8	8.9	19.5	0.7	-2.9	-1.8	3.6	3.0	3.0	3.4	2.3	4.4
Leg fat-free mass (left)	0.7	3.8	7.1	-0.2	1.4	0.6	-2.6	-2.2	-2.2	-2.7	-1.7	-2.4
Trunk fat percentage	0.9	3.5	7.1	0.6	-2.7	-1.8	1.4	2.5	2.5	1.3	0.6	2.1
Hand grip strength (right)	0.4	1.2	3.0	-1.7	-0.6	-1.1	-1.3	-0.8	-0.8	-1.7	-0.6	-0.7
Townsend deprivation index at recruitment	0.8	1.1	2.8	-0.9	0.5	0.7	-1.1	-1.7	-1.7	-0.5	-0.8	-0.8
Current tobacco smoking	0.4	0.7	2.6	-1.6	0.3	-0.2	-0.8	-1.1	-1.1	-0.0	-0.1	-0.7
Average weekly fortified wine intake	1.3	1.5	3.6	-0.4	0.2	-1.6	-1.9	-1.4	-1.4	-1.0	-1.1	-1.2
Maternal smoking around birth	0.2	0.3	0.9	0.9	0.2	-1.0	-0.2	0.3	0.3	-0.3	0.6	-0.6
Fed-up feelings	0.6	1.1	4.6	0.7	2.2	1.4	1.0	-0.0	-0.0	0.6	1.2	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	4.0	-0.9	0.8	2.0	0.6	-0.2	-0.2	0.3	-0.5	-1.0
Relative age voice broke	0.3	0.5	1.8	1.1	0.6	0.7	0.6	0.4	0.4	0.2	1.3	0.2
Taking other prescription medications	0.4	0.6	3.4	0.6	-0.3	1.9	0.5	0.4	0.4	0.6	-0.3	-0.3
Age when periods started (menarche)	0.2	0.5	2.3	-0.1	0.6	0.9	-0.0	-0.1	-0.1	-1.5	-0.2	0.7
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	4.9	0.3	-0.7	-2.2	-0.2	0.2	0.2	0.5	-0.1	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.2	0.2	-0.0	-1.5	-0.2	0.1	0.1	0.8	1.3	-0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.5	-0.7	-0.7	-0.7	0.0	0.5	0.5	-0.3	-0.7	0.4
Qualifications: CSEs or equivalent	0.4	0.5	2.4	-1.5	-0.3	-1.4	-0.1	0.2	0.2	-0.3	-0.4	0.0
Serious illness, injury or assault to yourself	2.2	2.7	6.2	-1.1	0.7	0.6	-2.0	-2.5	-2.5	-1.0	-1.3	-1.7
High blood pressure	0.5	1.3	3.4	1.1	1.1	-1.8	-0.4	-0.9	-0.9	0.5	1.5	1.4
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.7	-0.1	-0.8	0.8	0.1	-0.0	-0.0	-0.4	-0.1	0.2
Multivitamins +/- minerals	3.5	4.4	10.2	-3.2	0.1	-0.2	-2.8	-2.3	-2.3	-1.6	-2.1	-2.0
Stomach or abdominal pain in last month	0.6	0.8	1.8	1.3	-1.3	-0.5	0.5	0.9	0.9	0.3	0.0	1.1
Supplements: Glucosamine	0.1	0.1	0.5	-0.7	0.1	0.3	-0.4	-0.3	-0.3	-0.5	-0.2	0.0
Diverticular disease/diverticulitis (self-reported)	8.4	10.0	20.5	2.6	-2.2	-1.1	3.5	3.6	3.6	4.5	2.1	3.6
Medication: Atenolol	1.5	1.9	3.7	0.1	0.9	-1.4	-1.8	-1.8	-1.8	-1.9	-1.0	0.1
Medication: Levothyroxine sodium	2.1	3.5	6.0	1.6	-1.1	-1.8	1.6	1.8	1.8	2.3	1.8	2.4
Sitting height	0.3	1.8	4.1	-0.9	0.5	-0.2	-1.5	-1.6	-1.6	-2.0	-1.5	-1.4
Chronic bronchitis/emphysema (father)	0.5	0.6	2.5	0.2	-0.6	0.3	-0.8	-0.7	-0.7	-0.9	-1.6	-0.4
High blood pressure (mother)	0.5	0.6	2.4	0.8	0.4	0.2	1.0	0.5	0.5	0.4	1.6	0.9
Body mass index (BMI)	0.3	1.3	3.7	-0.2	-1.9	-1.8	-0.1	1.3	1.3	0.7	-0.1	0.4
Impedance of leg (left)	1.6	7.7	17.4	0.6	-2.6	-2.1	3.2	2.9	2.9	3.0	2.2	4.2
Leg predicted mass (left)	0.7	3.8	7.0	-0.2	1.4	0.5	-2.6	-2.2	-2.2	-2.6	-1.7	-2.4
Trunk fat mass	0.4	1.8	3.6	0.6	-1.9	-1.7	0.6	1.7	1.7	0.6	0.3	1.5
Waist circumference	0.1	0.3	0.8	0.9	-0.6	-0.3	0.1	0.9	0.9	0.1	0.1	0.4
Number of incorrect matches in round	2.9	4.9	11.8	-0.7	3.4	1.5	-2.2	-2.1	-2.1	-2.5	-0.3	-3.1
Past tobacco smoking	0.2	0.3	0.9	0.1	0.8	1.0	-0.3	-0.1	-0.1	-0.1	0.4	-0.9
Alcohol usually taken with meals	0.3	0.4	1.5	1.2	-0.3	0.8	0.4	0.0	0.0	0.8	0.4	0.8
Nervous feelings	0.3	0.5	2.7	-1.6	-1.0	0.4	0.0	0.0	0.0	0.2	-0.9	0.3
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.6	4.3	-2.1	0.4	0.7	-0.9	-1.3	-1.3	-1.0	-1.5	-1.6
Hearing difficulty/problems with background noise	0.2	0.4	1.2	-0.3	-0.5	1.1	0.6	0.2	0.2	1.0	0.0	0.5
Hair/balding pattern: Pattern 2	0.2	0.2	0.7	0.3	0.8	0.4	0.2	-0.4	-0.4	0.3	0.5	0.1
Had menopause	2.5	3.2	5.6	1.4	-0.8	1.4	1.9	2.3	2.3	2.4	1.4	1.4
Had other major operations	0.5	0.6	1.9	-1.3	-0.9	-0.3	-0.4	-0.4	-0.4	-0.4	-1.4	-0.5
Forced vital capacity (FVC)	0.5	1.9	3.2	-1.5	-1.4	-1.0	-1.8	-0.9	-0.9	-1.5	-1.2	-1.7
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	2.4	-0.3	-0.2	-1.6	-0.6	-0.4	-0.4	1.0	0.9	0.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	1.6	0.3	0.2	0.8	1.2	1.1	1.1	1.1	1.3	0.4
Qualifications: None of the above	0.3	0.7	1.7	0.6	-0.9	-0.6	0.4	1.1	1.1	1.3	-0.1	-0.8
Financial difficulties in last 2 years	0.5	0.7	1.5	-0.9	1.2	-0.1	-0.7	-1.1	-1.1	-0.9	0.1	-0.2
Mouth/teeth dental problems	0.1	0.2	0.6	0.3	0.8	0.2	0.2	0.1	0.1	-0.4	0.6	0.2
Heart attack	0.4	0.5	1.2	-0.1	-0.5	0.1	0.8	0.6	0.6	1.0	0.6	1.1
Allergy	0.2	0.4	0.8	-0.9	0.9	-0.7	-0.7	-0.7	-0.7	-0.1	0.2	-0.4
Pain all over the body in last month	0.5	0.5	1.4	-0.8	-1.2	0.5	-0.3	0.6	0.6	-1.0	-0.6	-0.4
Diabetes (self-reported)	0.2	0.3	0.5	-0.4	-0.6	0.7	0.3	0.7	0.7	0.6	0.3	-0.5
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.4	-0.5	-1.0	0.8	1.0	0.8	0.8	-0.0	0.0	1.2
Medication: Ramipril	0.3	0.4	1.9	-1.2	-0.4	-1.4	-0.3	0.0	0.0	0.4	0.2	0.5
Medication: Simvastatin	0.8	1.1	3.2	1.4	0.0	-1.8	0.3	0.0	0.0	1.2	1.2	1.3
Fluid intelligence score	0.5	1.0	2.9	-0.3	-1.2	-0.3	1.3	1.1	1.1	0.7	-0.2	1.7
Illnesses of siblings	0.4	0.6	1.6	0.7	1.0	1.3	0.7	0.1	0.1	-0.5	1.2	0.6
Neuroticism score	0.6	1.3	4.9	-0.3	2.2	2.0	0.1	-0.8	-0.8	-0.6	0.1	-0.9
Weight	0.1	0.3	0.9	0.3	-0.6	-1.0	-0.8	0.0	0.0	-0.6	-0.5	-0.1
Impedance of arm (right)	0.6	2.8	6.0	1.0	-0.8	0.5	2.4	1.9	1.9	1.0	1.7	2.4
Arm fat percentage (right)	0.9	3.7	7.7	0.2	-2.8	-2.2	1.2	2.6	2.6	1.4	0.8	1.9
Trunk fat-free mass	0.6	3.5	5.6	0.5	2.1	0.6	-2.2	-2.4	-2.4	-2.3	-1.3	-1.9
Hip circumference	0.2	0.7	1.7	0.9	-1.0	-0.2	0.6	1.3	1.3	0.8	0.4	0.5
Time employed in main current job	0.1	0.1	0.4	-0.2	0.4	0.3	0.3	0.2	0.2	-0.6	-0.4	0.5
Alcohol intake versus 10 years previously	1.2	1.8	6.3	-0.9	-1.9	-2.5	-0.2	0.7	0.7	2.1	-0.3	0.5
Father’s age at death	1.7	2.3	7.2	-0.0	2.7	2.1	-0.8	-1.9	-1.9	-1.3	-0.2	-0.4
Worrier / anxious feelings	0.6	1.2	4.8	-2.2	0.6	0.6	-0.2	0.1	0.1	-1.5	-1.0	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.2	-0.1	-1.1	0.9	-0.4	-0.1	-0.1	-0.3	-0.6	0.3
Falls in the last year	0.6	0.9	2.5	-0.3	-0.3	0.5	-1.6	-1.2	-1.2	-0.8	-0.6	-0.9
Hair/balding pattern: Pattern 3	0.4	0.7	1.6	0.5	0.1	0.9	1.0	0.9	0.9	0.8	1.3	-0.0
Number of live births	0.4	0.6	1.4	1.2	-0.2	-0.1	0.8	1.0	1.0	0.7	0.7	0.9
Forced expiratory volume in 1-second (FEV1)	0.5	1.5	4.4	-2.1	-1.6	-1.6	-1.2	-0.5	-0.5	-1.0	-0.6	-1.0
Pulse rate	1.8	3.1	6.9	-2.6	-0.2	0.3	-1.9	-1.8	-1.8	-1.7	-2.2	-1.8
Happiness	0.5	0.6	1.5	-0.6	-1.0	-1.2	0.6	0.7	0.7	0.1	-0.7	0.6
Noisy workplace	0.7	0.9	3.3	-0.1	-0.1	0.1	-0.9	-0.2	-0.2	-1.2	-1.8	-1.5
Qualifications: A levels/AS levels or equivalent	0.3	0.8	3.4	0.0	0.3	1.9	-0.3	-0.3	-0.3	-1.1	-0.5	-1.3
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	3.3	-1.1	-1.1	0.3	-0.7	-0.3	-0.3	-1.4	-1.8	-1.8
Mouth/teeth dental problems: Dentures	1.0	1.7	6.1	1.7	-0.0	1.5	1.4	0.8	0.8	2.5	0.8	0.3
Asthma	0.3	0.6	2.6	1.1	0.8	1.6	0.3	0.4	0.4	-0.5	-0.3	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.8	-0.6	0.8	-0.8	0.7	0.6	0.6	-0.9	0.5	-0.4
Medication: Cholesterol lowering	0.4	0.6	1.8	0.2	0.5	-1.3	-0.8	-0.9	-0.9	0.7	0.9	0.5
Depression (self-reported)	0.5	0.6	2.5	-1.6	-0.2	0.3	0.1	0.4	0.4	0.1	-0.2	-1.6
Medication: Lansoprazole	1.6	1.8	5.0	0.9	2.1	2.2	-0.7	-1.3	-1.3	-0.3	-0.4	-1.3
Prospective memory result	0.7	0.8	3.4	0.8	1.3	0.3	-0.5	-0.6	-0.6	-1.9	-0.6	-0.6
Lung cancer (father)	1.0	1.2	2.7	0.8	0.4	0.1	1.2	1.4	1.4	1.4	1.7	0.2
Illnesses of mother	0.5	0.6	1.7	-0.8	-0.8	-0.8	-0.9	-0.6	-0.6	-0.2	-1.3	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	10.7	-3.3	-2.0	-1.3	-1.9	-1.1	-1.1	-1.2	-1.9	-1.7
Pulse wave Arterial Stiffness index	0.9	1.0	3.3	1.8	0.0	1.7	1.0	0.4	0.4	1.1	0.4	-0.4
Impedance of arm (left)	0.6	2.6	5.9	0.9	-0.9	0.5	2.4	1.9	1.9	1.1	1.6	2.3
Arm fat mass (right)	0.3	1.2	3.2	0.2	-1.8	-1.7	0.1	1.4	1.4	0.2	-0.0	1.0
Trunk predicted mass	0.7	3.8	6.2	0.5	2.2	0.6	-2.3	-2.5	-2.5	-2.3	-1.3	-2.0
Standing height	0.5	4.9	11.4	1.3	2.8	1.8	-1.7	-2.8	-2.8	-3.4	-1.1	-1.1
Length of working week for main job	0.6	0.7	1.9	1.4	0.8	1.3	-0.5	-0.8	-0.8	-0.6	0.1	0.4
Exposure to tobacco smoke at home	0.5	0.5	1.1	-0.1	0.5	-1.1	1.0	0.2	0.2	0.6	0.8	1.0
Breastfed as a baby	0.6	0.7	1.9	-0.8	-0.7	-0.8	-1.4	-1.0	-1.0	-0.5	-0.7	0.0
Tense / ‘highly strung’	0.3	0.4	1.2	-0.8	1.1	0.7	0.1	-0.3	-0.3	-0.5	0.8	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	6.0	-2.4	0.3	1.4	0.6	0.6	0.6	-0.3	0.2	-1.1
Hair/balding pattern: Pattern 4	0.3	0.8	1.6	0.1	0.5	-0.2	1.1	1.2	1.2	1.0	1.0	1.0
Birth weight of first child	1.9	3.5	9.6	0.1	0.1	1.9	-1.6	-1.1	-1.1	-2.7	-2.3	-3.1
Peak expiratory flow (PEF)	0.8	1.9	7.3	-1.7	-1.4	-2.7	-0.2	0.0	0.0	-0.0	1.2	1.8
Pulse wave reflection index	0.8	0.9	1.6	0.9	-0.8	0.4	1.1	1.3	1.3	1.1	0.9	-0.6
Ever highly irritable/argumentative for 2 days	0.9	1.1	4.2	0.1	1.8	2.1	0.8	-0.3	-0.3	0.5	1.0	-0.8
Loud music exposure frequency	1.0	1.1	3.2	0.8	0.4	-0.1	1.3	1.0	1.0	0.5	1.4	1.8
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	2.1	-1.3	0.2	0.1	-0.8	-1.1	-1.1	-1.1	-1.4	-0.5
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	2.4	-1.2	-0.3	-0.3	-1.5	-0.9	-0.9	-1.5	-1.1	-0.6
Blood clot in the leg (DVT)	0.9	1.1	2.2	0.4	-1.1	-1.0	1.2	1.5	1.5	1.2	-0.3	0.7
Medication: Paracetamol	0.6	1.0	3.6	-1.1	-1.9	-0.6	0.0	0.9	0.9	-1.0	-0.9	0.1
Headache pain in last month	0.1	0.1	0.8	-0.3	-0.9	-0.2	0.1	0.1	0.1	-0.4	-0.2	0.5
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	4.7	0.1	-0.6	2.2	1.0	1.1	1.1	-0.6	-0.8	-0.7
Glaucoma (self-reported)	2.8	3.2	7.5	2.0	0.1	-0.1	2.1	1.4	1.4	2.7	2.1	2.2
Gout (self-reported)	1.1	1.6	6.4	0.2	1.9	-0.5	1.1	-0.2	-0.2	2.5	1.5	0.6
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	3.5	1.5	-0.5	-0.6	1.1	1.0	1.0	1.9	1.6	1.2
Medication: Amlodipine	0.2	0.3	1.0	-0.4	0.6	-1.0	-0.1	-0.4	-0.4	0.5	-0.5	-0.4
Medication: Ventolin 100micrograms inhaler	0.8	1.0	2.2	-1.1	-1.5	-0.9	-0.8	0.6	0.6	-1.1	-1.2	-0.8
Birth weight	0.5	1.1	3.6	-0.7	1.9	-0.4	-1.0	-1.4	-1.4	-0.4	-0.1	-0.3
Chronic bronchitis/emphysema (mother)	1.0	1.1	4.4	2.1	0.5	0.1	1.1	1.0	1.0	1.2	0.6	0.4
High blood pressure (siblings)	0.9	1.3	2.9	0.0	-1.7	-1.7	0.5	1.1	1.1	1.7	-0.2	0.2
Forced vital capacity (FVC), Best measure	0.8	3.1	5.1	-2.3	-2.2	-1.2	-2.1	-1.1	-1.1	-1.4	-2.1	-1.7
Body fat percentage	1.5	6.0	11.6	0.4	-3.4	-2.6	1.7	3.1	3.1	2.1	1.1	2.6
Leg fat percentage (right)	2.4	8.8	16.0	-0.1	-4.0	-3.6	2.0	3.4	3.4	3.1	1.5	3.4
Arm fat-free mass (right)	0.6	3.0	5.5	0.2	1.6	-0.1	-2.4	-2.2	-2.2	-2.0	-1.3	-1.8
Exposure to tobacco smoke outside home	0.1	0.2	0.6	0.3	0.2	-0.7	-0.0	0.0	0.0	0.6	0.2	0.7
Comparative body size at age 10	1.9	5.3	16.2	-0.9	4.0	0.9	-2.0	-3.1	-3.1	-0.7	-0.2	-2.4
Number of full brothers	3.3	4.1	9.5	-1.5	0.9	-0.0	-2.5	-2.0	-2.0	-2.9	-3.1	-1.4
Worry too long after embarrassment	1.2	2.0	5.4	0.3	2.3	1.1	-1.0	-1.5	-1.5	-2.0	-0.7	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	3.6	-1.2	0.9	1.9	-0.4	-0.8	-0.8	-0.7	0.3	-1.9
Wheeze or whistling in the chest in last year	0.3	0.4	1.1	-0.8	0.1	0.1	-0.9	-0.4	-0.4	-1.1	-0.8	-0.5
Number of children fathered	1.0	1.2	3.9	-0.4	-0.7	-1.1	-1.4	0.0	0.0	-2.0	-1.1	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	4.0	0.1	1.2	-0.1	0.0	-0.4	-0.4	-0.4	2.0	0.3
Age at first live birth	1.7	3.0	10.8	-0.9	1.8	0.6	-1.7	-1.9	-1.9	-3.3	-0.6	-1.1
Pulse wave peak to peak time	0.7	0.8	2.4	-1.5	0.2	-1.6	-0.8	-0.4	-0.4	-1.0	-0.3	0.6
Health satisfaction	0.5	0.7	2.2	-0.5	0.8	1.2	0.5	0.3	0.3	-0.5	-0.9	-1.5
Shortness of breath walking on level ground	3.0	3.5	9.8	-1.4	0.2	0.8	-1.7	-1.6	-1.6	-1.8	-2.8	-3.1
Qualifications: College or University degree	1.3	4.1	8.3	-1.3	1.4	0.9	-2.4	-2.5	-2.5	-2.9	-1.2	-2.2
Eye problems/disorders: None of the above	0.2	0.2	0.6	-0.6	-0.1	0.2	0.8	0.1	0.1	-0.3	-0.7	0.1
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.1	0.3	-1.1	-1.5	-0.4	-0.1	-0.1	0.9	0.7	0.6
Emphysema/chronic bronchitis	1.1	1.3	4.1	2.0	-1.0	0.1	1.1	1.4	1.4	0.1	0.3	1.1
Medication for pain relief, constipation, heartburn	0.6	1.0	2.7	0.9	1.2	1.6	-0.4	-1.3	-1.3	0.8	-0.2	-0.1
Neck or shoulder pain in last month	0.4	0.5	1.4	-0.6	1.2	0.9	-0.2	-0.8	-0.8	-0.7	0.3	-0.5
Medication: Blood pressure	0.7	1.2	6.6	-0.1	0.4	-2.6	-0.8	-0.9	-0.9	0.4	0.7	1.1
Angina (self-reported)	0.7	0.9	5.3	-2.3	0.1	-0.1	-0.3	-0.8	-0.8	0.2	-0.3	-1.2
Migraine (self-reported)	2.7	3.4	7.3	-1.3	-1.2	-1.1	-2.3	-1.6	-1.6	-2.7	-2.7	-1.2
Medication: Ibuprofen	0.3	0.3	1.3	-0.2	0.7	-0.4	0.2	0.2	0.2	-1.1	0.3	-0.8
Medication: Allopurinol	1.5	2.0	7.6	1.3	0.9	-0.1	2.0	0.8	0.8	2.8	1.2	1.0
Medication: Omeprazole	0.6	0.7	2.1	-0.5	0.1	0.7	0.6	0.9	0.9	0.9	0.4	-1.4
Medication: Seretide 50 evohaler	0.0	0.0	0.1	0.1	0.1	-0.0	0.0	-0.1	-0.1	-0.1	-0.2	0.2
Mean time to correctly identify matches	1.0	1.9	6.4	-1.2	-0.4	0.2	-1.6	-1.1	-1.1	-1.6	-2.5	-1.1
Heart disease (mother)	0.9	1.1	3.8	1.1	1.5	1.9	0.6	0.4	0.4	-0.0	1.2	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.1	4.6	-0.4	-0.6	-2.1	-1.6	-0.6	-0.6	-0.6	-1.2	-0.2
Whole body fat mass	0.6	2.6	5.9	0.4	-2.4	-2.0	0.8	2.1	2.1	1.1	0.5	1.6
Leg fat mass (right)	0.8	3.2	7.3	-0.2	-2.6	-2.7	0.7	2.0	2.0	1.5	0.6	1.9
Arm predicted mass (right)	0.5	2.5	4.9	0.4	1.4	-0.2	-2.2	-2.1	-2.1	-1.8	-1.2	-1.6
Pulse rate, automated reading	0.3	1.1	3.3	-1.8	-1.8	-0.6	-0.4	0.0	0.0	-0.5	-1.2	0.8
Alcohol intake frequency.	0.2	0.5	1.5	-0.0	-0.2	-1.2	0.5	0.9	0.9	0.8	0.2	-0.4
Comparative height size at age 10	0.1	0.8	1.6	0.2	0.9	0.4	-0.8	-1.3	-1.3	-1.3	0.2	-0.8
Number of full sisters	0.2	0.3	1.6	-0.2	-0.1	-0.2	-0.2	-0.3	-0.3	1.3	0.6	-0.4
Suffer from ‘nerves’	0.9	1.3	5.7	-0.2	2.4	1.8	0.3	-0.7	-0.7	-0.1	1.1	-0.9
Overall health rating	0.3	0.7	1.5	-1.1	-1.2	0.2	0.9	1.1	1.1	0.4	-0.5	0.0
Chest pain or discomfort	0.5	0.8	1.8	-1.0	-0.4	0.7	-0.8	-0.7	-0.7	-1.2	-1.3	-0.8
Had major operations	1.3	1.5	4.4	-0.4	0.7	1.6	-1.3	-0.8	-0.8	-2.1	-0.9	-1.5
Age at last live birth	3.4	5.0	11.2	-0.4	2.6	1.6	-2.2	-2.7	-2.7	-3.4	-0.7	-1.9
Family relationship satisfaction	0.7	0.9	2.4	-1.0	0.4	-0.7	-0.8	-1.0	-1.0	-1.1	-1.6	-0.6
Leg pain on walking	0.6	0.8	2.8	-0.9	0.9	1.7	-0.4	-0.5	-0.5	-0.3	-0.3	-1.4
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	2.5	0.6	-1.6	0.9	0.7	1.0	1.0	0.2	0.7	1.0
Commuting to job workplace: Car/motor vehicle	2.5	2.8	7.3	1.2	0.1	-0.8	1.8	1.6	1.6	2.1	2.7	1.8
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.5	0.4	0.7	-0.0	0.8	0.8	0.8	1.0	1.2	0.6
Medication: Aspirin	0.7	1.0	2.8	-1.3	0.9	-0.6	-1.1	-0.8	-0.8	-1.7	0.5	-0.7
Supplements: Vitamin C	0.6	0.7	2.0	-1.4	-0.2	-0.3	-0.9	-0.9	-0.9	-0.4	-1.1	-0.7
Knee pain experienced in last month	2.6	4.0	9.3	-2.0	0.9	1.2	-2.0	-2.3	-2.3	-0.8	-2.3	-3.1
Hypertension (Self-reported)	0.5	1.4	3.2	1.1	1.3	-1.8	-0.4	-0.9	-0.9	0.6	1.5	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.0	0.4	-1.0	-0.9	-0.6	0.1	0.1	-0.3	-0.8	-0.3
Illnesses of father: Heart disease	1.6	2.2	4.5	-1.8	0.7	-0.5	-1.8	-1.3	-1.3	-1.2	-1.9	-2.1
Illnesses of siblings: Diabetes	0.7	0.9	4.4	-1.3	-0.4	-2.1	-0.3	0.1	0.1	-0.2	-0.5	1.1
Smoking status: Previous	0.3	0.4	0.9	0.8	-0.0	-0.5	0.9	0.7	0.7	0.4	0.6	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	3.9	0.2	1.6	1.1	-0.9	-1.8	-1.8	-2.0	-0.2	-0.0
Whole body fat-free mass	0.8	4.3	7.2	0.1	1.9	0.5	-2.7	-2.5	-2.5	-2.6	-1.6	-2.3
Leg fat-free mass (right)	0.9	5.0	9.3	-0.3	1.9	0.7	-2.9	-2.4	-2.4	-3.0	-1.8	-2.8
Arm fat percentage (left)	0.9	3.6	7.3	0.0	-2.7	-2.1	1.2	2.6	2.6	1.5	0.8	1.8
Average weekly red wine intake	0.5	0.8	2.2	1.5	1.5	1.1	-0.1	-0.7	-0.7	0.3	0.8	0.1
Handedness (chirality/laterality): Left-handed	3.3	4.0	8.3	-0.9	2.0	2.5	-1.6	-1.6	-1.6	-2.9	-1.8	-2.3
Mood swings	1.4	2.6	6.1	1.4	0.9	0.6	2.5	1.8	1.8	0.9	2.5	1.0
Loneliness, isolation	0.2	0.3	1.3	-1.1	-0.6	0.8	-0.3	-0.3	-0.3	-0.2	-0.5	0.2
Long-standing illness, disability or infirmity	0.6	0.8	1.9	0.2	-0.6	1.4	1.0	1.2	1.2	1.1	0.4	-0.2
Ever had bowel cancer screening	0.4	0.5	1.5	0.0	1.2	-0.2	0.6	0.3	0.3	0.7	1.2	0.5
Diabetes diagnosed by doctor	0.2	0.4	1.8	-0.4	-0.3	1.3	0.4	0.5	0.5	0.6	0.3	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.0	0.7	0.0	1.0	0.3	-0.1	-0.1	0.2	0.2	0.4
Friendships satisfaction	0.6	0.7	1.5	-0.6	0.1	-0.9	-1.2	-0.8	-0.8	-0.6	-1.0	-1.1
Qualifications: nursing, teaching	1.5	2.4	5.6	1.7	0.2	2.4	1.7	1.9	1.9	0.6	1.6	0.5
Commuting to job workplace: Walk	1.1	1.2	6.0	-2.4	-0.2	-0.5	-0.8	-0.9	-0.9	-0.8	-1.1	-0.7
Eye problems/disorders: Cataract	0.8	0.9	2.2	0.1	0.7	0.4	-1.5	-1.4	-1.4	-0.3	0.3	-1.0
Mouth/teeth dental problems: Mouth ulcers	1.5	2.3	6.1	-1.8	-0.2	-0.6	-1.8	-1.0	-1.0	-2.5	-1.9	-1.4
Medication for cholesterol	0.8	1.2	2.1	1.1	-0.5	-0.0	1.3	1.5	1.5	1.5	1.0	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	3.5	0.5	-1.0	-1.0	1.3	1.0	1.0	1.8	1.9	1.3
Back pain experienced in last month	0.7	1.0	5.7	-0.8	0.1	1.4	-0.6	-0.2	-0.2	-0.1	-0.5	-2.4
Mineral and other dietary supplements	1.0	1.4	4.1	2.0	-0.1	-0.9	1.5	1.1	1.1	1.2	0.9	0.8
Breast cancer (self-reported)	0.5	0.6	1.0	-0.5	0.9	-0.0	-0.9	-1.0	-1.0	-0.8	-0.7	0.1
Asthma (self-reported)	0.4	0.7	3.3	1.2	0.9	1.8	0.2	0.3	0.3	-0.6	-0.3	-0.6
Osteoporosis (self-reported)	1.0	1.2	4.2	1.6	-0.3	0.3	1.0	0.4	0.4	1.2	1.0	2.1
Osteoarthritis (self-reported)	0.9	1.1	5.9	0.6	1.4	2.4	0.2	-0.4	-0.4	0.9	0.7	-0.1
Medication: Aspirin	0.6	0.7	1.8	-1.1	0.8	-0.8	-1.0	-0.6	-0.6	-1.4	0.6	-0.3
Medication: Gliclazide	0.6	0.6	2.6	-0.9	-1.6	-0.5	0.3	0.7	0.7	0.4	-0.9	-0.2
Illnesses of father: None of the above (group 1)	2.2	2.7	6.4	1.5	-0.1	1.2	2.1	1.2	1.2	2.5	1.8	1.9
Smoking status: Current	0.5	0.8	2.7	-1.6	0.2	-0.3	-0.9	-1.3	-1.3	-0.1	-0.3	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.8	13.9	-1.8	-3.7	-2.5	0.8	2.0	2.0	1.6	-0.5	0.6
Whole body water mass	0.7	4.0	6.6	0.3	1.9	0.5	-2.6	-2.4	-2.4	-2.5	-1.6	-2.3
Leg predicted mass (right)	0.9	5.0	9.5	-0.2	1.9	0.7	-2.8	-2.4	-2.4	-3.1	-1.8	-2.9
Arm fat mass (left)	0.4	1.6	3.4	0.4	-1.8	-1.6	0.5	1.7	1.7	0.7	0.3	1.2
Number of self-reported non-cancer illnesses	0.1	0.2	1.0	0.6	1.0	0.3	0.5	-0.1	-0.1	0.2	0.4	0.5
Average weekly champagne plus white wine intake	0.8	1.1	1.8	-0.9	1.3	0.5	-0.4	-1.1	-1.1	-1.1	-1.1	-1.4
Miserableness	0.3	0.6	3.1	-1.8	-0.1	-0.1	1.0	0.6	0.6	0.3	-0.2	0.1
Guilty feelings	1.6	2.4	5.2	-0.9	2.3	1.3	-1.5	-1.9	-1.9	-1.1	0.2	-2.0
Wears glasses or contact lenses	1.1	1.3	2.7	1.3	1.3	1.5	1.3	0.7	0.7	0.8	1.6	-0.0
Ever taken oral contraceptive pill	1.1	1.3	7.1	0.6	1.4	0.2	0.7	0.1	0.1	0.6	2.7	1.1
Hearing aid user	1.5	1.7	6.5	0.3	-2.5	-1.6	0.0	0.9	0.9	1.9	-0.6	0.3
Mother’s age at death	1.1	1.4	3.8	-0.3	-1.5	-1.9	-0.3	0.5	0.5	-1.9	-1.1	1.1
Financial situation satisfaction	0.4	0.5	1.8	-0.2	-0.3	-0.4	1.1	0.6	0.6	0.0	-0.1	1.4
Tinnitus: Yes, now most or all of the time	1.1	1.3	3.5	1.2	0.1	-0.6	1.1	1.1	1.1	1.2	1.9	1.2
Commuting to job workplace: Public transport	3.2	3.9	9.0	-1.6	-0.6	-1.0	-2.4	-2.1	-2.1	-2.0	-3.0	-1.8
Eye problems/disorders: Glaucoma	4.1	4.9	9.4	2.1	0.1	-1.2	2.3	1.9	1.9	3.1	2.9	2.8
Medication: Blood pressure	0.2	0.4	1.0	-0.3	-0.4	-0.7	-0.7	-1.0	-1.0	0.4	-0.7	0.0
Pain type(s) experienced in last month: Hip pain	0.7	0.8	4.7	1.2	0.4	-0.1	0.7	0.1	0.1	2.2	0.6	0.6
Supplements: Fish oil (including cod liver oil)	1.5	2.0	4.1	-1.7	0.9	0.7	-1.7	-1.6	-1.6	-2.0	-0.9	-0.9
High cholesterol (Self-reported)	0.9	1.5	6.1	0.3	-1.7	-2.5	-0.9	-0.6	-0.6	1.2	-0.8	1.1
Medication: Bendroflumethiazide	0.4	0.6	1.7	-0.8	0.1	-0.9	-1.0	-0.8	-0.8	-0.4	-1.3	-0.6
Medication: Paracetamol	0.8	1.2	3.3	-1.3	-1.4	-0.6	-1.0	-0.1	-0.1	-1.8	-1.5	-0.3
Medication: Lisinopril	1.2	1.6	8.9	-1.7	-1.2	-3.0	-0.2	0.3	0.3	-0.0	-0.9	0.4
Medication: Atorvastatin	0.3	0.3	2.3	-1.5	-0.1	-0.1	-0.5	-0.4	-0.4	0.2	-0.1	0.3
Illnesses of father: High blood pressure	1.0	1.2	2.8	-1.7	-0.0	-1.7	-1.0	-0.4	-0.4	-1.5	-0.7	-1.1
Alcohol drinker status: Never	0.2	0.3	0.6	-0.3	0.1	-0.6	-0.7	-0.3	-0.3	-0.8	-0.6	-0.4
Ever smoked	0.5	0.9	2.7	-1.2	-1.1	-1.6	-0.6	-0.6	-0.6	-0.4	-1.1	0.4
Basal metabolic rate	0.5	2.5	4.8	0.2	1.2	0.0	-2.2	-1.8	-1.8	-2.1	-1.4	-1.7
Leg fat percentage (left)	2.3	8.1	15.3	-0.3	-3.9	-3.8	1.7	3.3	3.3	2.8	1.3	3.1
Arm fat-free mass (left)	0.4	2.3	4.6	0.4	1.2	-0.3	-2.1	-1.8	-1.8	-1.9	-1.2	-1.6
Number of operations (self-reported)	0.5	0.7	3.0	-0.4	-0.3	1.2	-0.5	-0.4	-0.4	-0.9	-1.7	-0.5
Average weekly beer plus cider intake	1.5	2.1	8.8	-0.0	-3.0	-1.8	0.8	1.4	1.4	1.0	0.3	1.2
Irritability	0.6	1.0	3.5	-0.7	1.1	1.6	-0.0	-0.5	-0.5	-0.6	-0.7	-1.9
Risk taking	0.6	0.9	2.6	-0.3	-0.2	0.9	-1.1	-0.5	-0.5	-1.3	-0.9	-1.6
Ever had prostate specific antigen (PSA) test	0.9	1.1	3.3	-1.8	0.0	-0.4	-0.9	-0.7	-0.7	-0.3	-1.5	-1.5
Fractured/broken bones in last 5 years	0.7	0.9	5.2	0.6	1.3	2.3	0.4	0.2	0.2	-0.3	0.8	-0.5
Age started oral contraceptive pill	1.8	2.2	5.4	-0.8	-0.3	-0.4	-2.3	-1.5	-1.5	-2.2	-1.8	-0.9
Diastolic blood pressure, automated reading	0.5	1.5	5.0	0.5	0.2	-2.2	-0.3	-0.3	-0.3	0.2	1.8	2.2
Ever depressed for a whole week	0.3	0.4	1.4	-1.2	-0.1	-0.8	0.2	0.2	0.2	0.4	0.9	0.6
Unable to work because of sickness or disability	0.4	0.5	2.0	-0.9	-0.2	1.4	0.2	0.4	0.4	0.8	-0.1	-0.6
Commuting to job workplace: Cycle	2.2	2.7	5.5	-1.1	1.5	1.2	-1.0	-2.4	-2.4	-1.6	-1.7	-1.3
Myopia	0.2	0.3	1.0	-0.9	-0.3	-1.0	0.1	-0.1	-0.1	0.2	-0.4	-0.3
Vascular/heart problems diagnosed by doctor	0.4	1.2	3.0	-0.2	-1.0	1.7	1.0	1.5	1.5	-0.2	-0.4	-0.9
Cholesterol lowering medication	0.7	1.0	2.2	-0.0	-1.1	-1.5	0.7	0.7	0.7	1.3	0.3	1.5
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.9	0.1	0.1	1.7	0.6	0.9	0.9	0.1	-0.1	-2.0
Pain experienced in last month	0.5	0.9	1.6	1.2	-0.1	-0.6	1.0	0.9	0.9	1.1	0.8	1.2
Supplements: Calcium	1.1	1.2	2.4	-0.8	0.3	1.1	-1.3	-1.1	-1.1	-1.6	-0.7	-1.3
Basal cell carcinoma (self-reported)	3.4	4.0	11.8	1.6	-0.1	-1.4	2.0	1.3	1.3	3.4	2.4	2.5
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.3	-0.3	-0.6	-0.3	0.6	0.5	0.5	1.0	0.6	1.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.1	0.3	-1.2	-1.1	0.9	1.4	1.4	1.0	-0.3	0.6
Heart disease (siblings)	1.4	1.7	5.4	-1.8	-1.8	-1.3	-1.0	-0.1	-0.1	-0.2	-2.3	-0.9
Alcohol drinker status: Previous	0.5	0.6	1.1	0.8	1.1	0.8	0.9	0.8	0.8	-0.1	0.0	-0.7
Pack years of smoking	0.5	0.7	2.4	-1.1	-0.3	0.8	-0.3	-0.9	-0.9	1.5	-0.5	-0.5
Impedance of whole body	0.9	4.4	10.7	0.8	-1.7	-0.8	2.7	2.2	2.2	2.0	2.0	3.3
Leg fat mass (left)	0.7	2.8	7.2	-0.2	-2.5	-2.7	0.6	1.8	1.8	1.3	0.4	1.7
Arm predicted mass (left)	0.4	2.1	5.0	0.2	0.9	-0.6	-2.2	-1.8	-1.8	-1.7	-1.2	-1.5