[Hub]/) : Traits : Blood White Count : ← →

chr7:2,032,803-3,581,391

Best TWAS P=1.34e-20 · Best GWAS P=3.44e-20 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	9.2	9.3	1.3e-20	0.95	0.00	1.00	TRUE
10	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	8.9	9.3	1.8e-20	0.91	0.03	0.97	FALSE
5	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	8.9	9.0	2.4e-19	0.86	0.01	0.99	FALSE
11	GTEx	Lung	GNA12	0.16	0.08	enet	21	0.12	1.2e-09	9.2	9.0	2.6e-19	0.78	0.01	0.99	FALSE
12	GTEx	Nerve Tibial	GNA12	0.31	0.34	lasso	7	0.36	9.6e-27	8.0	8.9	3.7e-19	0.83	0.96	0.04	FALSE
14	GTEx	Skin Sun Exposed Lower leg	GNA12	0.17	0.16	lasso	3	0.18	1.3e-14	7.8	8.9	4.3e-19	0.84	0.22	0.78	FALSE
6	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	7.9	8.8	1.6e-18	0.82	0.05	0.82	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	8.5	8.7	5.1e-18	0.88	0.48	0.52	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	7.9	8.6	8.2e-18	0.82	0.05	0.94	FALSE
3	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	8.9	8.4	3.5e-17	0.85	0.02	0.98	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	GNA12	0.10	0.15	lasso	3	0.12	4.2e-07	-8.0	8.4	4.7e-17	0.57	0.36	0.62	FALSE
17	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	8.8	8.4	4.8e-17	0.87	0.03	0.89	FALSE
18	METSIM	Adipose	GNA12	0.07	0.05	lasso	3	0.05	3.3e-08	8.2	8.3	1.2e-16	0.74	0.48	0.52	FALSE
1	GTEx	Adipose Subcutaneous	GNA12	0.11	0.08	lasso	4	0.07	1.3e-06	7.9	8.2	2.9e-16	0.71	0.61	0.38	FALSE
16	GTEx	Stomach	GNA12	0.18	0.16	lasso	2	0.13	6.6e-07	7.9	8.0	1.1e-15	0.71	0.57	0.42	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	-5.3	7.9	2.1e-15	0.75	0.05	0.78	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GNA12	0.03	0.04	lasso	1	0.04	3.0e-05	7.9	7.9	2.5e-15	0.67	0.08	0.75	FALSE
15	GTEx	Small Intestine Terminal Ileum	GNA12	0.34	0.20	lasso	5	0.16	2.4e-04	8.2	7.9	3.4e-15	0.73	0.09	0.72	FALSE
21	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	-6.2	7.6	3.4e-14	0.75	0.01	0.62	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	8.9	-7.5	4.9e-14	-0.88	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	AMZ1	0.04	0.04	lasso	3	0.02	1.3e-03	-6.2	-7.1	1.7e-12	-0.67	0.02	0.94	FALSE
2	GTEx	Adipose Visceral Omentum	GNA12	0.28	0.06	enet	46	0.08	8.0e-05	-8.0	6.8	9.1e-12	0.38	0.13	0.68	FALSE
7	GTEx	Colon Transverse	GNA12	0.19	0.08	lasso	4	0.10	2.3e-05	-5.6	6.8	1.1e-11	0.62	0.18	0.80	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	AMZ1	0.32	0.04	enet	19	0.20	3.3e-19	7.7	-6.7	2.2e-11	-0.61	0.11	0.89	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	AMZ1	0.08	0.01	blup	71	0.05	1.3e-05	7.9	-6.3	3.6e-10	-0.67	0.03	0.88	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	GNA12	0.09	0.00	blup	103	0.03	9.3e-03	8.0	5.2	1.6e-07	0.48	0.04	0.12	FALSE