[Hub]/) : Traits : Blood White Count :

chr7:2,032,803-3,581,391

Best TWAS P=1.34e-20 · Best GWAS P=3.44e-20 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous GNA12 0.11 0.08 lasso 4 0.07 1.3e-06 7.9 8.2 2.9e-16 0.71 0.61 0.38 FALSE
2 GTEx Adipose Visceral Omentum GNA12 0.28 0.06 enet 46 0.08 8.0e-05 -8.0 6.8 9.1e-12 0.38 0.13 0.68 FALSE
3 GTEx Artery Tibial GNA12 0.24 0.13 enet 20 0.22 3.5e-17 8.9 8.4 3.5e-17 0.85 0.02 0.98 FALSE
4 GTEx Cells EBV-transformed lymphocytes GNA12 0.46 0.51 lasso 5 0.50 7.9e-19 8.5 8.7 5.1e-18 0.88 0.48 0.52 FALSE
5 GTEx Cells Transformed fibroblasts GNA12 0.21 0.11 lasso 11 0.15 1.7e-11 8.9 9.0 2.4e-19 0.86 0.01 0.99 FALSE
6 GTEx Colon Sigmoid GNA12 0.14 0.05 lasso 3 0.03 3.6e-02 7.9 8.8 1.6e-18 0.82 0.05 0.82 FALSE
7 GTEx Colon Transverse GNA12 0.19 0.08 lasso 4 0.10 2.3e-05 -5.6 6.8 1.1e-11 0.62 0.18 0.80 FALSE
8 GTEx Esophagus Gastroesophageal Junction GNA12 0.20 0.12 lasso 6 0.12 3.4e-05 7.9 8.6 8.2e-18 0.82 0.05 0.94 FALSE
9 GTEx Esophagus Mucosa GNA12 0.16 0.13 lasso 3 0.13 3.0e-09 9.2 9.3 1.3e-20 0.95 0.00 1.00 TRUE
10 GTEx Esophagus Muscularis GNA12 0.32 0.31 lasso 3 0.34 2.1e-21 8.9 9.3 1.8e-20 0.91 0.03 0.97 FALSE
11 GTEx Lung GNA12 0.16 0.08 enet 21 0.12 1.2e-09 9.2 9.0 2.6e-19 0.78 0.01 0.99 FALSE
12 GTEx Nerve Tibial GNA12 0.31 0.34 lasso 7 0.36 9.6e-27 8.0 8.9 3.7e-19 0.83 0.96 0.04 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic GNA12 0.10 0.15 lasso 3 0.12 4.2e-07 -8.0 8.4 4.7e-17 0.57 0.36 0.62 FALSE
14 GTEx Skin Sun Exposed Lower leg GNA12 0.17 0.16 lasso 3 0.18 1.3e-14 7.8 8.9 4.3e-19 0.84 0.22 0.78 FALSE
15 GTEx Small Intestine Terminal Ileum GNA12 0.34 0.20 lasso 5 0.16 2.4e-04 8.2 7.9 3.4e-15 0.73 0.09 0.72 FALSE
16 GTEx Stomach GNA12 0.18 0.16 lasso 2 0.13 6.6e-07 7.9 8.0 1.1e-15 0.71 0.57 0.42 FALSE
17 GTEx Whole Blood GNA12 0.09 0.01 enet 4 0.00 3.3e-01 8.8 8.4 4.8e-17 0.87 0.03 0.89 FALSE
18 METSIM Adipose GNA12 0.07 0.05 lasso 3 0.05 3.3e-08 8.2 8.3 1.2e-16 0.74 0.48 0.52 FALSE
19 ROSMAP Brain Pre-frontal Cortex AMZ1 0.09 0.05 lasso 6 0.04 2.4e-06 8.9 -7.5 4.9e-14 -0.88 0.02 0.98 FALSE
20 The Cancer Genome Atlas Colon Adenocarcinoma GNA12 0.09 0.00 blup 103 0.03 9.3e-03 8.0 5.2 1.6e-07 0.48 0.04 0.12 FALSE
21 The Cancer Genome Atlas Esophageal Carcinoma AMZ1 0.18 0.05 blup 69 0.05 1.4e-02 -6.2 7.6 3.4e-14 0.75 0.01 0.62 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GNA12 0.03 0.04 lasso 1 0.04 3.0e-05 7.9 7.9 2.5e-15 0.67 0.08 0.75 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma AMZ1 0.04 0.04 lasso 3 0.02 1.3e-03 -6.2 -7.1 1.7e-12 -0.67 0.02 0.94 FALSE
24 The Cancer Genome Atlas Lung Adenocarcinoma GNA12 0.03 0.01 enet 7 0.02 1.5e-03 -5.3 7.9 2.1e-15 0.75 0.05 0.78 FALSE
25 The Cancer Genome Atlas Prostate Adenocarcinoma AMZ1 0.08 0.01 blup 71 0.05 1.3e-05 7.9 -6.3 3.6e-10 -0.67 0.03 0.88 FALSE
26 The Cancer Genome Atlas Thyroid Carcinoma AMZ1 0.32 0.04 enet 19 0.20 3.3e-19 7.7 -6.7 2.2e-11 -0.61 0.11 0.89 FALSE