TWAS
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Usage
Models
Genes
Traits
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Traits
:
Blood White Count
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chr7:22,478,797-24,382,726
Best TWAS P=1.48e-08 · Best GWAS P=9.84e-17 conditioned to 3.26e-11
22.5M
23M
23.5M
24M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Cerebellum
AK3P3
0.27
0.15
enet
23
0.14
8.4e-05
1.1
-5.7
1.5e-08
-0.31
0.32
0.13
TRUE
2
GTEx
Esophagus Mucosa
CCDC126
0.12
0.03
lasso
7
0.01
4.3e-02
5.0
-5.4
6.4e-08
-0.05
0.06
0.68
TRUE