Best TWAS P=1.16e-14 · Best GWAS P=9.63e-15 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | ZNF713 | 0.22 | 0.18 | lasso | 8 | 0.14 | 7.0e-06 | 6.7 | -6.3 | 3.5e-10 | -0.56 | 0.33 | 0.14 | FALSE |
| 2 | GTEx | Esophagus Mucosa | CCT6A | 0.06 | 0.03 | lasso | 2 | 0.02 | 1.1e-02 | 7.7 | 7.7 | 1.2e-14 | 1.00 | 0.01 | 0.96 | TRUE |
| 3 | GTEx | Esophagus Mucosa | PSPH | 0.11 | 0.00 | enet | 24 | 0.01 | 4.4e-02 | 1.1 | 6.3 | 4.0e-10 | 0.67 | 0.02 | 0.84 | FALSE |
| 4 | GTEx | Lung | ZNF713 | 0.10 | 0.08 | enet | 10 | 0.06 | 4.0e-05 | -5.6 | -5.3 | 1.3e-07 | -0.45 | 0.63 | 0.04 | FALSE |
| 5 | GTEx | Prostate | ZNF713 | 0.19 | 0.10 | lasso | 2 | 0.07 | 1.0e-02 | -5.6 | -5.8 | 9.0e-09 | -0.49 | 0.04 | 0.48 | FALSE |
| 6 | GTEx | Skin Not Sun Exposed Suprapubic | GBAS | 0.08 | 0.00 | lasso | 9 | 0.01 | 6.3e-02 | -3.5 | 5.6 | 1.7e-08 | 0.73 | 0.02 | 0.83 | FALSE |
| 7 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SUMF2 | 0.04 | 0.04 | enet | 5 | 0.04 | 1.4e-05 | -5.7 | -5.7 | 1.2e-08 | -0.59 | 0.04 | 0.96 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | PHKG1 | 0.07 | 0.06 | enet | 4 | 0.06 | 3.9e-06 | 5.9 | 6.0 | 1.4e-09 | 0.68 | 0.20 | 0.79 | FALSE |