Hub : Genes

PHKG1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Brain Lower Grade Glioma 0.0367 0.0216 2.6e-03 0.020 0.029 0.028 NA 0.025 2.2e-03 2.7e-04 3.1e-04 NA 0.00072
2 TCGA Thyroid Carcinoma 0.0690 0.0290 1.8e-06 0.061 0.043 0.056 NA 0.034 1.4e-06 4.5e-05 3.9e-06 NA 0.00030

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 1.1 1.7 2.9 -0.7 1.7
Bipolar Disorder or Schizophrenia 2.3 5.6 6.4 -2.2 2.5
Depressed Affect (Nagel 2018) 0.5 1.0 1.6 -0.7 -1.3
Depression (Nagel 2018) 0.3 0.4 0.8 0.1 -0.9
Intelligence (Savage-Jansen 2018) 0.1 0.2 0.2 0.4 -0.5
Neuroticism (Nagel 2018) 0.9 2.0 3.7 0.5 -1.9
Schizophrenia (2018) 2.1 4.3 5.0 -2.2 1.9
Schizophrenia vs Biploar Disorder 1.7 2.3 4.5 0.2 -2.1
Worry (Nagel 2018) 0.3 0.7 1.2 0.4 -1.1
Alzheimer’s Disease (in mother) 0.8 1.0 1.8 -1.3 0.4
Alzheimer’s Disease (in father) 3.1 3.4 3.4 -1.8 1.8
Alzheimer’s Disease (including proxy) 0.6 0.8 1.3 -1.2 0.6
Crohns Disease (2017) 1.4 3.0 5.7 0.6 2.4
Irritable Bowel Disease (IBD) 0.7 1.7 3.3 0.3 1.8
Ulcerative Colitis (UC) 0.2 0.3 0.4 -0.5 0.6
Major Depression (MDD) 4.0 4.9 8.9 -3.0 0.9
Reaction Time 0.1 0.1 0.3 -0.1 0.5
Verbal and Numeric Reasoning (VNR) 0.2 0.5 0.7 0.5 -0.8
Breast Cancer 0.0 0.1 0.1 -0.3 0.3
Ovarian Cancer 0.7 0.9 1.4 -0.6 1.2
Prostate Cancer 1.6 2.2 4.5 -0.1 -2.1
Age at First Birth 1.7 2.4 4.8 0.2 2.2
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.2 0.3 0.6 -0.7 0.3
Coronary Artery Disease (CAD) 0.6 0.7 1.4 -0.2 1.2
Crohns Disease (2012) 1.0 1.6 3.1 0.4 1.8
Mean Putamen Volume 3.2 3.6 6.6 -2.6 0.8
Fasting Glucose 0.4 0.5 1.0 1.0 -0.2
HbA1C 6.4 7.1 8.6 2.9 -2.4
HDL Cholesterol 0.1 0.1 0.2 -0.2 -0.5
LDL Cholesterol 0.3 0.4 0.9 0.0 0.9
Lupus 0.3 0.5 0.8 0.9 0.3
Neuroticism (2016) 0.3 0.4 0.8 -0.9 -0.2
Primary Biliary Cirrhosis 0.7 1.0 1.7 -1.3 -0.5
Rheumatoid Arthritis 0.9 1.2 2.4 -0.1 1.6
Schizophrenia (2014) 3.0 6.7 10.4 -3.2 1.7
Triglycerides 0.8 1.4 2.8 -0.1 1.7
Type 2 Diabetes (T2D) (2012) 0.0 0.0 0.0 0.0 0.0
Ulcerative Colitis 0.1 0.2 0.3 0.6 0.2
Blood Eosinophil Count 0.0 0.1 0.2 -0.1 -0.5
Blood Platelet Count 0.3 3.8 7.0 -0.7 2.6
Blood Red Count 1.9 18.3 31.4 2.3 -5.6
Blood White Count 2.8 20.6 36.6 -2.2 6.0
Heel T-Score 0.0 0.1 0.2 0.4 -0.1
BMI 0.4 2.2 4.1 -2.0 -0.5
Height 4.2 80.6 83.0 9.1 -8.8
Waist Hip Ratio (WHR) 0.8 3.4 4.8 -1.4 2.2
Systolic Blood Pressure 1.9 9.8 19.3 -0.5 4.4
Smoking Status 1.7 4.0 7.0 1.0 2.6
Allergy or Eczema 0.1 0.3 0.6 0.1 -0.8
Cardiovascular Disease 0.0 0.0 0.1 -0.2 -0.1
Hypothyroidism (self reported) 0.0 0.1 0.1 -0.3 -0.2
Respiratory disease 0.6 1.3 2.1 -0.7 1.5
Type 2 Diabetes (T2D) (2018) 0.8 1.5 2.9 -0.2 1.7
Lung FEV1/FVC ratio 0.3 1.4 2.1 1.5 -0.8
Lung FVC 0.0 0.1 0.2 0.4 -0.3
Neuroticism 0.2 0.4 0.7 -0.8 -0.3
Chronotype (morning person) 0.2 0.4 0.4 -0.6 0.6
Hair Pigment 0.1 2.6 3.1 -1.5 1.8
Tanning 0.1 1.2 1.3 1.1 -1.1
Hand grip strength (left) 0.0 0.1 0.2 -0.4 0.3
Number of treatments/medications taken 0.1 0.2 0.2 -0.3 -0.5
Average weekly spirits intake 0.7 0.9 1.6 -1.2 0.5
Sensitivity / hurt feelings 0.5 0.8 1.3 0.5 -1.1
Frequency of depressed mood in last 2 weeks 0.2 0.2 0.4 -0.3 0.6
Hearing difficulty/problems: Yes 0.6 0.9 1.7 -1.3 0.4
Relative age of first facial hair 0.3 0.7 0.7 -0.8 0.8
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 0.6 -0.7 0.4
Ever used hormone-replacement therapy (HRT) 0.2 0.3 0.4 -0.6 0.4
Ever had hysterectomy (womb removed) 1.8 2.0 3.6 -1.9 0.7
Systolic blood pressure, automated reading 1.4 4.0 6.5 -1.2 2.5
Eye problems/disorders: Diabetes related eye disease 0.0 0.0 0.1 -0.3 -0.0
Angina 0.4 0.5 1.0 -1.0 0.1
Medication for hormone replacement therapy 0.8 0.9 1.6 0.3 1.3
Vitamin and mineral supplements 0.4 0.5 0.5 -0.7 -0.7
Supplements: Zinc 0.1 0.1 0.1 -0.2 0.3
Medication: Co-codamol 2.9 3.4 4.8 -2.2 1.4
Medication: Metformin 1.3 1.8 3.5 0.3 1.9
Diabetes (father) 0.5 0.6 1.2 0.2 1.1
Diabetes (mother) 1.3 1.6 3.1 -0.4 1.8
Severe depression (siblings) 0.1 0.1 0.1 -0.2 -0.3
Pack years adult smoking proportion 1.9 2.9 5.2 -0.7 2.3
Impedance of leg (right) 0.2 0.8 1.5 -0.5 1.2
Leg fat-free mass (left) 1.8 9.5 9.7 3.1 -3.1
Trunk fat percentage 0.4 1.5 2.4 -1.5 0.8
Hand grip strength (right) 0.1 0.2 0.3 0.3 -0.5
Townsend deprivation index at recruitment 2.8 4.0 5.9 -1.4 2.4
Current tobacco smoking 1.4 2.3 4.2 0.6 2.0
Average weekly fortified wine intake 0.4 0.5 0.9 -0.1 -1.0
Maternal smoking around birth 0.4 0.5 0.6 0.7 0.7
Fed-up feelings 0.8 1.5 2.9 -1.7 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.1 0.3 0.5 -0.1
Relative age voice broke 0.5 0.7 1.5 0.2 1.2
Taking other prescription medications 0.5 0.8 1.4 0.4 -1.2
Age when periods started (menarche) 1.6 3.8 4.2 -1.8 2.1
Bilateral oophorectomy (both ovaries removed) 2.2 2.5 2.9 -1.7 1.5
Heel bone mineral density (BMD) T-score, automated (left) 0.0 0.1 0.1 -0.0 0.4
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 0.7 -0.1 0.9
Qualifications: CSEs or equivalent 0.4 0.6 1.1 0.2 1.1
Serious illness, injury or assault to yourself 0.1 0.1 0.1 0.2 -0.3
High blood pressure 0.4 1.2 1.6 1.3 -0.9
Hayfever, allergic rhinitis or eczema 0.7 1.6 2.9 0.5 -1.7
Multivitamins +/- minerals 0.2 0.3 0.4 0.6 0.4
Stomach or abdominal pain in last month 1.7 2.1 4.0 -0.6 2.0
Supplements: Glucosamine 1.0 1.4 2.3 0.7 -1.5
Diverticular disease/diverticulitis (self-reported) 1.8 2.1 2.9 -1.1 1.7
Medication: Atenolol 0.5 0.6 1.2 -0.3 -1.1
Medication: Levothyroxine sodium 0.3 0.5 0.6 -0.6 -0.8
Sitting height 2.8 19.8 21.6 4.7 -4.2
Chronic bronchitis/emphysema (father) 0.0 0.0 0.1 0.3 0.1
High blood pressure (mother) 2.5 3.5 4.8 1.5 -2.2
Body mass index (BMI) 0.4 1.8 2.2 -1.5 1.2
Impedance of leg (left) 0.4 2.2 3.4 -0.9 1.8
Leg predicted mass (left) 1.7 9.0 9.2 3.0 -3.0
Trunk fat mass 0.0 0.2 0.2 -0.4 -0.3
Waist circumference 0.3 1.0 2.0 -1.4 0.2
Number of incorrect matches in round 0.3 0.4 0.8 0.9 -0.3
Past tobacco smoking 0.4 0.7 1.1 -0.5 -1.0
Alcohol usually taken with meals 2.2 3.6 6.8 0.6 -2.6
Nervous feelings 0.1 0.2 0.3 -0.5 -0.2
Frequency of tenseness / restlessness in last 2 weeks 1.2 1.9 3.5 1.9 -0.5
Hearing difficulty/problems with background noise 0.3 0.4 0.6 -0.8 -0.5
Hair/balding pattern: Pattern 2 3.6 4.6 5.0 -2.1 2.2
Had menopause 0.2 0.3 0.3 -0.5 -0.5
Had other major operations 0.1 0.2 0.2 -0.5 0.3
Forced vital capacity (FVC) 2.1 8.1 8.1 2.9 -2.8
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.2 0.3 0.2 0.6
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 0.6 0.8 -0.3
Qualifications: None of the above 1.6 3.5 5.7 -1.1 2.4
Financial difficulties in last 2 years 0.5 0.6 0.8 0.9 0.7
Mouth/teeth dental problems 0.6 0.9 1.8 1.4 -0.0
Heart attack 1.5 1.9 2.7 1.7 1.1
Allergy 0.3 0.7 1.1 -0.5 1.1
Pain all over the body in last month 2.9 3.1 4.3 2.1 -1.4
Diabetes (self-reported) 0.4 0.6 1.2 -0.0 1.1
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 0.5 -0.1 -0.7
Medication: Ramipril 0.1 0.2 0.3 0.5 -0.2
Medication: Simvastatin 1.2 1.7 3.2 0.5 -1.8
Fluid intelligence score 0.2 0.3 0.5 -0.7 -0.4
Illnesses of siblings 0.3 0.4 0.4 -0.6 -0.5
Neuroticism score 0.2 0.3 0.6 0.2 -0.8
Weight 0.4 2.0 2.2 1.3 -1.5
Impedance of arm (right) 0.0 0.1 0.2 -0.5 -0.3
Arm fat percentage (right) 0.8 3.1 4.7 -2.2 1.2
Trunk fat-free mass 2.8 16.3 18.2 4.3 -3.8
Hip circumference 0.2 0.9 1.7 0.3 -1.3
Time employed in main current job 0.1 0.1 0.2 0.1 0.5
Alcohol intake versus 10 years previously 0.8 1.2 2.1 1.4 -0.6
Father’s age at death 1.2 1.7 1.7 -1.3 -1.3
Worrier / anxious feelings 0.7 1.3 1.5 1.0 -1.2
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 1.1 1.1 -0.5
Falls in the last year 0.9 1.2 2.0 -0.6 1.4
Hair/balding pattern: Pattern 3 0.6 0.9 1.7 -0.1 -1.3
Number of live births 0.0 0.0 0.1 -0.1 0.2
Forced expiratory volume in 1-second (FEV1) 2.1 7.1 7.4 2.7 -2.6
Pulse rate 0.7 1.2 1.7 0.8 1.3
Happiness 2.1 2.6 3.8 -1.1 2.0
Noisy workplace 0.3 0.4 0.7 -0.1 0.8
Qualifications: A levels/AS levels or equivalent 0.3 0.6 1.1 0.3 -1.1
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.1 0.4 -0.0
Mouth/teeth dental problems: Dentures 0.1 0.1 0.1 -0.4 -0.2
Asthma 0.2 0.3 0.6 0.2 0.8
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 1.3 -1.1 0.2
Medication: Cholesterol lowering 0.7 1.0 1.4 1.2 -0.8
Depression (self-reported) 0.1 0.1 0.1 0.2 -0.4
Medication: Lansoprazole 0.0 0.0 0.0 0.0 0.2
Prospective memory result 0.4 0.5 0.7 0.8 -0.5
Lung cancer (father) 0.5 0.6 1.1 1.0 -0.3
Illnesses of mother 0.0 0.0 0.0 -0.0 0.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.6 5.1 5.3 2.2 -2.3
Pulse wave Arterial Stiffness index 0.1 0.1 0.2 -0.2 -0.5
Impedance of arm (left) 0.0 0.1 0.2 -0.4 -0.0
Arm fat mass (right) 0.1 0.3 0.6 -0.8 -0.0
Trunk predicted mass 2.8 15.9 17.9 4.2 -3.7
Standing height 3.9 38.3 38.3 6.2 -6.2
Length of working week for main job 0.3 0.3 0.3 -0.6 0.6
Exposure to tobacco smoke at home 0.4 0.4 0.7 -0.4 0.9
Breastfed as a baby 1.7 2.1 4.0 2.0 -0.3
Tense / ‘highly strung’ 0.1 0.2 0.4 0.6 0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.1 0.1 0.1 0.2 0.3
Hair/balding pattern: Pattern 4 0.1 0.2 0.4 -0.2 0.6
Birth weight of first child 3.3 6.0 10.4 1.2 -3.2
Peak expiratory flow (PEF) 2.0 4.6 6.4 1.7 -2.5
Pulse wave reflection index 0.1 0.1 0.1 -0.0 -0.4
Ever highly irritable/argumentative for 2 days 0.4 0.5 1.0 -0.1 1.0
Loud music exposure frequency 1.7 1.9 3.5 1.9 0.5
Qualifications: O levels/GCSEs or equivalent 1.6 2.5 3.4 -1.3 -1.9
Mouth/teeth dental problems: Bleeding gums 0.3 0.3 0.6 0.8 0.1
Blood clot in the leg (DVT) 1.3 1.7 2.2 1.1 -1.5
Medication: Paracetamol 2.3 3.8 5.5 -2.3 1.4
Headache pain in last month 0.9 1.5 1.5 -1.2 -1.2
Medication for cholesterol, blood pressure or diabetes 0.8 1.4 1.7 -1.3 1.1
Glaucoma (self-reported) 1.2 1.5 2.7 1.7 0.4
Gout (self-reported) 0.9 1.2 2.0 -1.4 0.6
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 1.0 0.0 -1.0
Medication: Amlodipine 0.4 0.5 0.9 1.0 -0.4
Medication: Ventolin 100micrograms inhaler 1.3 1.7 1.8 1.3 -1.3
Birth weight 0.5 1.1 1.6 0.7 -1.3
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.2 0.5 -0.0
High blood pressure (siblings) 0.1 0.2 0.2 0.4 -0.4
Forced vital capacity (FVC), Best measure 1.4 5.1 5.2 2.2 -2.3
Body fat percentage 0.6 2.5 3.5 -1.9 1.2
Leg fat percentage (right) 1.2 4.3 5.0 -2.2 1.9
Arm fat-free mass (right) 1.9 10.0 12.9 3.6 -2.7
Exposure to tobacco smoke outside home 0.4 0.5 1.0 1.0 0.0
Comparative body size at age 10 0.0 0.1 0.1 -0.2 0.3
Number of full brothers 0.3 0.4 0.5 0.5 0.7
Worry too long after embarrassment 2.0 3.3 4.7 2.2 -1.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 0.9 1.8 1.3 -0.1
Wheeze or whistling in the chest in last year 0.2 0.4 0.6 -0.5 0.7
Number of children fathered 1.9 2.1 4.0 2.0 -0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 0.7 -0.8 -0.5
Age at first live birth 0.1 0.1 0.3 0.5 -0.2
Pulse wave peak to peak time 0.2 0.2 0.3 0.6 -0.1
Health satisfaction 0.0 0.1 0.1 -0.3 0.1
Shortness of breath walking on level ground 2.4 2.8 4.1 2.0 -1.2
Qualifications: College or University degree 0.0 0.1 0.1 -0.2 0.3
Eye problems/disorders: None of the above 3.7 4.3 8.2 -2.9 0.6
Mouth/teeth dental problems: Loose teeth 0.0 0.1 0.1 0.2 0.2
Emphysema/chronic bronchitis 0.5 0.5 0.6 -0.7 0.8
Medication for pain relief, constipation, heartburn 0.2 0.3 0.3 0.5 0.5
Neck or shoulder pain in last month 0.6 0.8 0.9 -1.0 0.8
Medication: Blood pressure 2.0 3.5 4.5 2.1 -1.6
Angina (self-reported) 0.6 0.8 1.6 -1.2 0.2
Migraine (self-reported) 3.1 3.8 5.5 -1.5 -2.4
Medication: Ibuprofen 2.2 2.6 3.4 -1.8 1.4
Medication: Allopurinol 1.2 1.7 3.2 -1.8 0.3
Medication: Omeprazole 0.5 0.6 1.2 -0.1 -1.1
Medication: Seretide 50 evohaler 0.6 0.7 1.2 1.1 -0.3
Mean time to correctly identify matches 0.0 0.1 0.1 0.3 0.1
Heart disease (mother) 2.0 2.4 4.8 0.1 2.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.1 1.3 1.7 -1.3 1.0
Whole body fat mass 0.0 0.2 0.3 -0.5 -0.1
Leg fat mass (right) 0.1 0.5 0.9 -0.9 0.3
Arm predicted mass (right) 2.1 10.8 13.5 3.7 -2.8
Pulse rate, automated reading 1.8 5.8 11.6 -0.3 3.4
Alcohol intake frequency. 0.1 0.3 0.4 -0.7 -0.4
Comparative height size at age 10 3.7 20.4 22.6 4.8 -4.3
Number of full sisters 0.5 0.6 0.8 -0.7 0.9
Suffer from ‘nerves’ 0.7 1.1 1.6 -1.3 -0.8
Overall health rating 0.1 0.2 0.4 -0.2 0.7
Chest pain or discomfort 0.5 0.8 1.4 -0.3 -1.2
Had major operations 0.5 0.5 0.6 -0.8 0.7
Age at last live birth 0.2 0.3 0.3 0.6 -0.5
Family relationship satisfaction 0.1 0.2 0.2 0.3 0.5
Leg pain on walking 0.5 0.6 1.3 -0.2 1.1
Qualifications: NVQ or HND or HNC or equivalent 0.8 0.9 1.4 -1.2 -0.7
Commuting to job workplace: Car/motor vehicle 0.5 0.6 1.0 1.0 0.4
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 0.4 -0.6 -0.3
Medication: Aspirin 0.2 0.2 0.3 -0.4 -0.5
Supplements: Vitamin C 0.3 0.3 0.4 -0.5 0.6
Knee pain experienced in last month 0.4 0.7 1.0 -1.0 -0.6
Hypertension (Self-reported) 0.4 1.1 1.4 1.2 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.8 1.4 0.4 -1.2
Illnesses of father: Heart disease 0.3 0.4 0.7 -0.1 0.9
Illnesses of siblings: Diabetes 0.8 0.9 1.7 1.3 -0.4
Smoking status: Previous 0.6 0.8 1.2 0.7 1.1
Forced expiratory volume in 1-second (FEV1), predicted 2.8 5.7 8.5 1.7 -2.9
Whole body fat-free mass 2.3 13.3 14.7 3.8 -3.4
Leg fat-free mass (right) 1.7 8.9 9.0 3.0 -3.0
Arm fat percentage (left) 0.7 3.0 4.1 -2.0 1.4
Average weekly red wine intake 1.4 2.1 2.8 -1.7 1.1
Handedness (chirality/laterality): Left-handed 0.4 0.5 0.9 -0.1 -1.0
Mood swings 0.1 0.2 0.4 -0.1 -0.6
Loneliness, isolation 0.4 0.6 0.9 0.5 0.9
Long-standing illness, disability or infirmity 0.2 0.3 0.6 0.8 -0.1
Ever had bowel cancer screening 0.5 0.6 1.2 -1.1 0.2
Diabetes diagnosed by doctor 0.7 1.1 2.1 -0.2 1.5
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.2 0.5 0.3
Friendships satisfaction 2.8 3.5 7.0 2.7 -0.2
Qualifications: nursing, teaching 0.1 0.1 0.3 0.1 -0.5
Commuting to job workplace: Walk 0.4 0.5 0.9 0.2 -0.9
Eye problems/disorders: Cataract 3.9 4.5 6.9 2.6 -1.4
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 0.9 -0.7 -0.9
Medication for cholesterol 0.3 0.4 0.7 -0.9 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 0.5 0.7 -0.2
Back pain experienced in last month 0.2 0.3 0.4 0.6 -0.4
Mineral and other dietary supplements 0.0 0.1 0.1 -0.2 0.3
Breast cancer (self-reported) 0.9 1.1 1.8 1.4 -0.5
Asthma (self-reported) 0.2 0.3 0.6 0.3 0.8
Osteoporosis (self-reported) 0.5 0.6 0.8 -0.9 -0.7
Osteoarthritis (self-reported) 0.9 1.1 1.4 0.9 -1.2
Medication: Aspirin 0.1 0.1 0.2 -0.4 -0.3
Medication: Gliclazide 1.2 1.3 1.9 -0.9 1.4
Illnesses of father: None of the above (group 1) 0.4 0.5 1.0 -0.1 -1.0
Smoking status: Current 1.2 1.9 3.5 0.6 1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 0.3 0.0 -0.6
Whole body water mass 2.3 13.1 14.1 3.8 -3.5
Leg predicted mass (right) 1.7 8.9 9.0 3.0 -3.0
Arm fat mass (left) 0.1 0.4 0.6 -0.8 0.3
Number of self-reported non-cancer illnesses 1.2 2.0 3.5 0.8 -1.9
Average weekly champagne plus white wine intake 0.9 1.3 2.5 -1.6 0.2
Miserableness 0.1 0.2 0.3 0.3 -0.5
Guilty feelings 0.2 0.3 0.4 0.4 -0.7
Wears glasses or contact lenses 1.5 1.8 2.4 -1.6 -1.1
Ever taken oral contraceptive pill 0.8 0.9 1.8 0.1 1.3
Hearing aid user 0.9 1.0 1.1 -1.0 1.0
Mother’s age at death 0.8 1.0 1.1 -0.9 1.1
Financial situation satisfaction 0.5 0.6 1.1 0.2 1.1
Tinnitus: Yes, now most or all of the time 1.4 1.6 1.9 -1.4 1.1
Commuting to job workplace: Public transport 0.6 0.7 1.0 -0.6 -1.0
Eye problems/disorders: Glaucoma 1.3 1.5 2.4 1.6 -0.8
Medication: Blood pressure 0.3 0.5 0.9 1.0 -0.4
Pain type(s) experienced in last month: Hip pain 0.2 0.2 0.4 -0.6 -0.2
Supplements: Fish oil (including cod liver oil) 0.3 0.4 0.5 0.5 -0.7
High cholesterol (Self-reported) 0.1 0.1 0.2 -0.1 -0.4
Medication: Bendroflumethiazide 2.3 3.4 5.8 1.0 -2.4
Medication: Paracetamol 2.7 4.1 6.9 -2.6 1.2
Medication: Lisinopril 2.0 2.5 4.7 2.2 -0.6
Medication: Atorvastatin 1.7 2.1 4.1 2.0 -0.4
Illnesses of father: High blood pressure 0.3 0.4 0.8 0.1 0.9
Alcohol drinker status: Never 0.2 0.2 0.4 0.0 0.6
Ever smoked 0.4 0.6 1.1 0.3 1.1
Basal metabolic rate 1.8 9.7 10.3 3.2 -3.0
Leg fat percentage (left) 1.5 5.5 5.9 -2.4 2.3
Arm fat-free mass (left) 1.3 6.8 8.1 2.8 -2.3
Number of operations (self-reported) 0.1 0.1 0.1 -0.4 0.3
Average weekly beer plus cider intake 0.1 0.2 0.3 0.6 -0.0
Irritability 0.2 0.4 0.7 0.9 0.0
Risk taking 2.6 3.8 6.0 -1.3 2.4
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.0 -0.0 -1.0
Fractured/broken bones in last 5 years 1.4 1.8 3.2 0.6 -1.8
Age started oral contraceptive pill 0.5 0.6 1.1 0.3 -1.1
Diastolic blood pressure, automated reading 0.1 0.4 0.6 -0.5 0.8
Ever depressed for a whole week 0.8 0.9 1.2 0.8 -1.1
Unable to work because of sickness or disability 0.2 0.2 0.4 0.0 0.7
Commuting to job workplace: Cycle 0.3 0.4 0.6 0.4 0.8
Myopia 0.4 0.5 0.6 -0.7 -0.8
Vascular/heart problems diagnosed by doctor 0.3 0.9 1.4 -1.2 0.6
Cholesterol lowering medication 0.0 0.1 0.1 0.3 -0.2
Medication: Omeprazole (e.g. Zanprol) 0.4 0.4 0.8 0.3 -0.9
Pain experienced in last month 0.2 0.3 0.4 0.7 0.4
Supplements: Calcium 0.0 0.0 0.1 0.1 -0.3
Basal cell carcinoma (self-reported) 0.1 0.1 0.2 0.5 -0.2
Heart attack/myocardial infarction (self-reported) 1.7 2.2 3.5 1.9 1.0
Deep venous thrombosis (DVT) (self-reported) 1.5 1.9 2.5 1.1 -1.6
Heart disease (siblings) 2.1 2.5 3.7 -1.2 1.9
Alcohol drinker status: Previous 0.2 0.2 0.3 -0.6 0.2
Pack years of smoking 1.3 2.0 3.7 -0.5 1.9
Impedance of whole body 0.1 0.6 0.7 -0.7 0.9
Leg fat mass (left) 0.2 0.7 1.1 -1.1 0.6
Arm predicted mass (left) 1.7 8.5 9.1 3.0 -2.8