Best TWAS P=1.73e-12 · Best GWAS P=1.14e-23 conditioned to 1.4e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PREX2 | 0.14 | 0.10 | lasso | 4 | 0.11 | 1.7e-06 | -6.9 | 6.7 | 1.6e-11 | -0.41 | 0.89 | 0.02 | FALSE |
| 2 | GTEx | Artery Tibial | PREX2 | 0.19 | 0.14 | lasso | 7 | 0.17 | 4.0e-13 | -6.9 | 6.6 | 4.8e-11 | -0.39 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Nerve Tibial | PREX2 | 0.13 | 0.00 | lasso | 9 | 0.00 | 4.4e-01 | -6.9 | 7.0 | 1.7e-12 | -0.44 | 0.09 | 0.10 | TRUE |