[Hub]/) : Traits : Blood White Count :

chr8:78,733,701-80,414,641

Best TWAS P=5.56e-13 · Best GWAS P=3.62e-29 conditioned to 1.17e-20

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex IL7 0.15 0.16 enet 25 0.16 1.5e-18 7.0 -5.4 6.5e-08 0.05 1.00 0.00 TRUE
2 GTEx Adipose Subcutaneous RP11-578O24.2 0.19 0.20 lasso 8 0.18 6.9e-15 7.0 -7.0 3.3e-12 0.14 1.00 0.00 FALSE
3 GTEx Adipose Visceral Omentum RP11-578O24.2 0.10 0.03 lasso 2 0.05 1.5e-03 7.0 -7.0 2.4e-12 0.15 0.55 0.04 FALSE
4 GTEx Artery Aorta RP11-578O24.2 0.23 0.25 lasso 6 0.23 4.1e-13 7.0 -6.8 1.4e-11 0.16 1.00 0.00 FALSE
5 GTEx Artery Coronary RP11-578O24.2 0.18 0.14 lasso 6 0.13 5.1e-05 6.9 -7.0 2.6e-12 0.15 0.72 0.02 FALSE
6 GTEx Artery Tibial RP11-578O24.2 0.18 0.18 lasso 4 0.17 3.6e-13 7.0 -7.0 2.8e-12 0.15 1.00 0.00 FALSE
7 GTEx Brain Cerebellar Hemisphere IL7 0.26 0.16 enet 18 0.18 2.4e-05 6.0 -5.8 7.5e-09 0.10 0.72 0.02 FALSE
8 GTEx Brain Cerebellar Hemisphere RP11-578O24.2 0.33 0.20 lasso 11 0.15 1.1e-04 7.0 -6.4 1.3e-10 0.13 0.33 0.04 FALSE
9 GTEx Brain Cerebellum IL7 0.24 0.31 enet 11 0.31 7.4e-10 6.9 -7.0 3.1e-12 0.15 0.99 0.00 FALSE
10 GTEx Brain Cerebellum RP11-578O24.2 0.22 0.18 lasso 9 0.14 6.0e-05 7.0 -7.1 1.6e-12 0.15 0.54 0.07 FALSE
11 GTEx Brain Cortex RP11-578O24.2 0.34 0.03 lasso 13 0.05 1.9e-02 6.9 -6.0 1.9e-09 0.06 0.12 0.13 FALSE
12 GTEx Breast Mammary Tissue RP11-578O24.2 0.21 0.16 lasso 1 0.12 5.8e-07 6.9 -6.9 4.0e-12 0.15 0.98 0.00 FALSE
13 GTEx Breast Mammary Tissue (Female) RP11-578O24.2 0.29 0.17 lasso 2 0.11 3.3e-04 6.9 -7.0 2.1e-12 0.15 0.26 0.11 FALSE
14 GTEx Cells Transformed fibroblasts RP11-578O24.2 0.20 0.22 lasso 7 0.22 2.2e-16 7.0 -7.0 2.1e-12 0.15 1.00 0.00 FALSE
15 GTEx Esophagus Gastroesophageal Junction RP11-578O24.2 0.22 0.03 enet 26 0.16 2.9e-06 4.9 -6.1 1.2e-09 0.08 0.29 0.06 FALSE
16 GTEx Esophagus Muscularis RP11-578O24.2 0.23 0.20 lasso 9 0.21 4.1e-13 7.0 -7.1 1.3e-12 0.15 1.00 0.00 FALSE
17 GTEx Heart Atrial Appendage RP11-578O24.2 0.12 0.10 lasso 3 0.08 2.1e-04 4.9 -6.2 7.8e-10 0.07 0.78 0.02 FALSE
18 GTEx Heart Left Ventricle RP11-578O24.2 0.10 0.09 lasso 7 0.09 1.3e-05 7.0 -7.0 2.6e-12 0.14 0.55 0.03 FALSE
19 GTEx Lung RP11-578O24.2 0.16 0.18 lasso 2 0.18 1.9e-13 7.0 -7.0 2.4e-12 0.15 1.00 0.00 FALSE
20 GTEx Muscle Skeletal RP11-578O24.2 0.07 0.05 enet 17 0.06 7.3e-07 7.0 -7.0 2.0e-12 0.14 0.99 0.00 FALSE
21 GTEx Nerve Tibial IL7 0.15 0.12 lasso 3 0.11 4.7e-08 7.0 -7.0 2.2e-12 0.15 1.00 0.00 FALSE
22 GTEx Nerve Tibial RP11-578O24.2 0.31 0.32 lasso 5 0.32 4.8e-23 7.0 -7.2 5.6e-13 0.15 1.00 0.00 TRUE
23 GTEx Ovary IL7 0.26 0.20 lasso 10 0.16 7.7e-05 6.9 -7.2 8.1e-13 0.15 0.25 0.08 FALSE
24 GTEx Ovary RP11-578O24.2 0.24 0.23 lasso 5 0.20 1.2e-05 7.0 -7.0 3.7e-12 0.15 0.33 0.04 FALSE
25 GTEx Pituitary RP11-578O24.2 0.24 0.21 lasso 8 0.20 7.6e-06 7.0 -7.0 3.4e-12 0.15 0.38 0.03 FALSE
26 GTEx Skin Not Sun Exposed Suprapubic RP11-578O24.2 0.23 0.17 lasso 7 0.16 3.2e-09 6.8 -7.0 2.8e-12 0.15 1.00 0.00 FALSE
27 GTEx Skin Sun Exposed Lower leg RP11-578O24.2 0.16 0.22 enet 17 0.22 1.8e-18 7.0 -7.2 6.5e-13 0.15 1.00 0.00 FALSE
28 GTEx Stomach RP11-578O24.2 0.09 0.05 lasso 2 0.02 3.3e-02 6.9 -7.2 9.0e-13 0.15 0.61 0.02 FALSE
29 GTEx Testis RP11-578O24.2 0.19 0.16 enet 14 0.15 3.1e-07 7.0 -5.6 1.9e-08 0.09 0.96 0.01 FALSE
30 GTEx Thyroid RP11-578O24.2 0.15 0.18 lasso 7 0.18 4.4e-14 6.9 -7.0 3.2e-12 0.15 1.00 0.00 FALSE
31 GTEx Whole Blood ZC2HC1A 0.07 0.08 lasso 2 0.06 1.9e-06 7.0 -7.0 2.4e-12 0.15 0.99 0.00 FALSE
32 NTR Blood FAM164A 0.06 0.06 lasso 3 0.06 3.6e-18 6.9 -6.7 2.2e-11 0.15 1.00 0.00 FALSE
33 YFS Blood PKIA 0.29 0.36 enet 41 0.39 1.4e-139 4.3 -5.7 1.3e-08 0.09 1.00 0.00 FALSE
34 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PKIA 0.05 0.04 blup 54 0.05 5.6e-06 4.1 -5.3 8.8e-08 0.09 0.20 0.79 FALSE
35 The Cancer Genome Atlas Lung Adenocarcinoma PKIA 0.03 0.00 blup 54 0.01 1.1e-02 6.9 -6.3 3.5e-10 0.04 0.00 0.74 FALSE
36 The Cancer Genome Atlas Thyroid Carcinoma IL7 0.04 0.02 enet 8 0.02 2.1e-03 6.1 -6.7 1.5e-11 0.18 0.08 0.38 FALSE